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The map label for this gene is clpX [H]

Identifier: 220917507

GI number: 220917507

Start: 2668031

End: 2669314

Strand: Reverse

Name: clpX [H]

Synonym: A2cp1_2407

Alternate gene names: 220917507

Gene position: 2669314-2668031 (Counterclockwise)

Preceding gene: 220917508

Following gene: 220917506

Centisome position: 53.07

GC content: 67.29

Gene sequence:

>1284_bases
GTGAGCCGGAAAGAGCATCACCACGGAAACCTGTCCTGCTCGTTCTGCGGCAAGGGCCAGCGGGAGGTCCGCAAGCTCAT
CGCGGGGCCCACGGTCTACATCTGCGACGAGTGCATCCGCCTCTGCAACGACATCATCGCGGAGGAGGCCGAGCGGGACG
AGGGCCGTCCGGCCGTCTCGCTGCCCACCCCGGCCGAGATCAAGAGCTTCCTCGACGATTACGTGGTCGGCCAGGACCGC
GCCAAGAAGGTCCTCTCGGTCGCGGTCTACAACCACTACAAGCGCGTCTACTCCCGCAAGCCCGCCCGGCCGGCGCGCCC
GGGGCAGGCGCGCGCGGCGCAGGACGACGTCGAGCTGCAGAAGTCGAACATCCTGCTCATCGGGCCCACCGGCTCGGGCA
AGACGCTGCTGGCGCAGTCGCTGGCGCGCTTCCTCAACGTTCCGTTCACCATCGCCGACGCGACCAGCCTCACCGAGGCG
GGCTACGTGGGCGAGGACGTCGAGAACATCATCCAGAACCTGCTGCACAACGCCGACTACGACGTGGAGAAGGCGTCGCG
CGGCATCGTCTACGTCGACGAGATCGACAAGATCGCGCGCAAGGGTGACACGCCCTCGCCGACCCGCGACGTGGGCGGGG
AAGGCGTCCAGCAGGCGCTCCTCAAGATCATCGAGGGCACGCGCGCCAACGTCACCCCGCGAGGCGGCAAGAAGTACAAC
CAGCAGGAGTACATCCAGGTCGACACCTCGAACGTGCTCTTCATCGTCGGCGGCGCGTTCTGCGGGCTGGAGCAGGTGAT
CCGCCGGCGCGTGGGCGTGAAGGGGCTCGGCTTCGGGGCCAAGATCGAGCGCAAGGAGGAGGCTAGCCTGGGCGAGCTGC
TCGCGCGGGTGGAGCCCGGCGACCTGGTGCGCTTCGGGATGATCCCCGAGTTCGTCGGCCGCCTGCCCATCATCGCGACG
CTGTCCGATCTGAGCGAGGACGACCTCGTCACCATCCTCACGCAGCCGAAGAACGCGCTCACGAAGCAGTACATCAAGCT
CTTCGACCTGGAGAAGGTGAAGCTCTCCTTCACCAAGGAGTCGCTGCGGGCGACCGCCCGCGAGGCGATGCGGCGCAAGT
CGGGCGCGCGCGGCCTGCGCGCCATCCTCGAGCAGGCCATGCTCGACATCATGTACGACGTGCCGTACCGGGAAGGCGTG
AAGGAGTGCAAGATCACCGAGGGTGTGATCGTCAACCGGGAGCCGCCGCTCCTGAGCTTCGAGAAGGAGAAGCGGACCGC
CTGA

Upstream 100 bases:

>100_bases
GGGGGAGCGGCCACGCGGCACCCTGGCTATATTCGAAGCCGGGCTCCGAATTCCGGGGACTCCCAGTTTGGTGGTAACAT
CCGATGCGTCGAGGGAACGC

Downstream 100 bases:

>100_bases
GCGCGTCCGCCTCGCCGACACCCCCAAGCGGCCGCCTCCGGGCGGCCGCTCGCACGTCCGGGACCCGACGCTGCGGCGGG
GTGCCGCCCCGCGCACGGTG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSRKEHHHGNLSCSFCGKGQREVRKLIAGPTVYICDECIRLCNDIIAEEAERDEGRPAVSLPTPAEIKSFLDDYVVGQDR
AKKVLSVAVYNHYKRVYSRKPARPARPGQARAAQDDVELQKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEA
GYVGEDVENIIQNLLHNADYDVEKASRGIVYVDEIDKIARKGDTPSPTRDVGGEGVQQALLKIIEGTRANVTPRGGKKYN
QQEYIQVDTSNVLFIVGGAFCGLEQVIRRRVGVKGLGFGAKIERKEEASLGELLARVEPGDLVRFGMIPEFVGRLPIIAT
LSDLSEDDLVTILTQPKNALTKQYIKLFDLEKVKLSFTKESLRATAREAMRRKSGARGLRAILEQAMLDIMYDVPYREGV
KECKITEGVIVNREPPLLSFEKEKRTA

Sequences:

>Translated_427_residues
MSRKEHHHGNLSCSFCGKGQREVRKLIAGPTVYICDECIRLCNDIIAEEAERDEGRPAVSLPTPAEIKSFLDDYVVGQDR
AKKVLSVAVYNHYKRVYSRKPARPARPGQARAAQDDVELQKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEA
GYVGEDVENIIQNLLHNADYDVEKASRGIVYVDEIDKIARKGDTPSPTRDVGGEGVQQALLKIIEGTRANVTPRGGKKYN
QQEYIQVDTSNVLFIVGGAFCGLEQVIRRRVGVKGLGFGAKIERKEEASLGELLARVEPGDLVRFGMIPEFVGRLPIIAT
LSDLSEDDLVTILTQPKNALTKQYIKLFDLEKVKLSFTKESLRATAREAMRRKSGARGLRAILEQAMLDIMYDVPYREGV
KECKITEGVIVNREPPLLSFEKEKRTA
>Mature_426_residues
SRKEHHHGNLSCSFCGKGQREVRKLIAGPTVYICDECIRLCNDIIAEEAERDEGRPAVSLPTPAEIKSFLDDYVVGQDRA
KKVLSVAVYNHYKRVYSRKPARPARPGQARAAQDDVELQKSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAG
YVGEDVENIIQNLLHNADYDVEKASRGIVYVDEIDKIARKGDTPSPTRDVGGEGVQQALLKIIEGTRANVTPRGGKKYNQ
QEYIQVDTSNVLFIVGGAFCGLEQVIRRRVGVKGLGFGAKIERKEEASLGELLARVEPGDLVRFGMIPEFVGRLPIIATL
SDLSEDDLVTILTQPKNALTKQYIKLFDLEKVKLSFTKESLRATAREAMRRKSGARGLRAILEQAMLDIMYDVPYREGVK
ECKITEGVIVNREPPLLSFEKEKRTA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=308, Percent_Identity=50.6493506493506, Blast_Score=298, Evalue=8e-81,
Organism=Escherichia coli, GI1786642, Length=423, Percent_Identity=63.5933806146572, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790366, Length=116, Percent_Identity=40.5172413793103, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982905, Length=318, Percent_Identity=44.9685534591195, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71982908, Length=321, Percent_Identity=44.8598130841121, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=38.9830508474576, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=259, Percent_Identity=42.0849420849421, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=410, Percent_Identity=40.2439024390244, Blast_Score=283, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24648291, Length=297, Percent_Identity=49.1582491582492, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24648289, Length=297, Percent_Identity=49.1582491582492, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47299; Mature: 47168

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKEHHHGNLSCSFCGKGQREVRKLIAGPTVYICDECIRLCNDIIAEEAERDEGRPAVS
CCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTPAEIKSFLDDYVVGQDRAKKVLSVAVYNHYKRVYSRKPARPARPGQARAAQDDVELQ
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
KSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGYVGEDVENIIQNLLHNADY
HCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCC
DVEKASRGIVYVDEIDKIARKGDTPSPTRDVGGEGVQQALLKIIEGTRANVTPRGGKKYN
CHHHHCCCEEEHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
QQEYIQVDTSNVLFIVGGAFCGLEQVIRRRVGVKGLGFGAKIERKEEASLGELLARVEPG
CCCEEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
DLVRFGMIPEFVGRLPIIATLSDLSEDDLVTILTQPKNALTKQYIKLFDLEKVKLSFTKE
CEEECCCCHHHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
SLRATAREAMRRKSGARGLRAILEQAMLDIMYDVPYREGVKECKITEGVIVNREPPLLSF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCC
EKEKRTA
CHHCCCC
>Mature Secondary Structure 
SRKEHHHGNLSCSFCGKGQREVRKLIAGPTVYICDECIRLCNDIIAEEAERDEGRPAVS
CCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTPAEIKSFLDDYVVGQDRAKKVLSVAVYNHYKRVYSRKPARPARPGQARAAQDDVELQ
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
KSNILLIGPTGSGKTLLAQSLARFLNVPFTIADATSLTEAGYVGEDVENIIQNLLHNADY
HCCEEEEECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCC
DVEKASRGIVYVDEIDKIARKGDTPSPTRDVGGEGVQQALLKIIEGTRANVTPRGGKKYN
CHHHHCCCEEEHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
QQEYIQVDTSNVLFIVGGAFCGLEQVIRRRVGVKGLGFGAKIERKEEASLGELLARVEPG
CCCEEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
DLVRFGMIPEFVGRLPIIATLSDLSEDDLVTILTQPKNALTKQYIKLFDLEKVKLSFTKE
CEEECCCCHHHHCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
SLRATAREAMRRKSGARGLRAILEQAMLDIMYDVPYREGVKECKITEGVIVNREPPLLSF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCCCCC
EKEKRTA
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA