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The map label for this gene is ykoG [H]

Identifier: 220917077

GI number: 220917077

Start: 2229027

End: 2229407

Strand: Direct

Name: ykoG [H]

Synonym: A2cp1_1974

Alternate gene names: 220917077

Gene position: 2229027-2229407 (Clockwise)

Preceding gene: 220917076

Following gene: 220917078

Centisome position: 44.32

GC content: 70.34

Gene sequence:

>381_bases
ATGAACGAACATCCGCTGGTCCTCGTCGTCGACGACGATCCCGACATCCTCGACGCCATCTGCGACATCCTCGAGGGCGA
GGGGTATCGCGTGGCGCGCGCACGGCACGGCCTCGAGGCGCTGGACCGCGTGGCCGAGGAGGAGCCGTCGATCATCCTCC
TCGACCTGATGATGCCGGTGATGGACGGGCTCGCGTTCGCGCAGGCGCTCCGCCAGCGGCGGAACGGGGCCGCGCGCATC
CCGATCGTCGTCATCTCGGCCGACGGGAACCCGCAGAAGGCGGCGTCGGTGGGCGCCCAGGGCTACCTGGCGAAGCCCTT
CGACATCGACGCGCTGCTGGCGCAGGTCACCGACATGGCCGGCCAGGCGATGCCAGGGTAG

Upstream 100 bases:

>100_bases
CGGCGCTGGGCGGGACGCTCTCGGTGGAGGAGGGAGCATTCGTGCTCACCCTTCCCGGAGCCGGAGCGTATACTGCGCGC
CCCGCATCGCCGCCGTTGCC

Downstream 100 bases:

>100_bases
CCGCGCCGGCGGCCAAAACCCCCCGCGCCACGCGGGCTTCGCTTGACAGCACGCGCGCCGGCGGGTAGAAAGCCCACCCT
TTCCAAGGCACGTCCTCCGC

Product: response regulator receiver protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MNEHPLVLVVDDDPDILDAICDILEGEGYRVARARHGLEALDRVAEEEPSIILLDLMMPVMDGLAFAQALRQRRNGAARI
PIVVISADGNPQKAASVGAQGYLAKPFDIDALLAQVTDMAGQAMPG

Sequences:

>Translated_126_residues
MNEHPLVLVVDDDPDILDAICDILEGEGYRVARARHGLEALDRVAEEEPSIILLDLMMPVMDGLAFAQALRQRRNGAARI
PIVVISADGNPQKAASVGAQGYLAKPFDIDALLAQVTDMAGQAMPG
>Mature_126_residues
MNEHPLVLVVDDDPDILDAICDILEGEGYRVARARHGLEALDRVAEEEPSIILLDLMMPVMDGLAFAQALRQRRNGAARI
PIVVISADGNPQKAASVGAQGYLAKPFDIDALLAQVTDMAGQAMPG

Specific function: Probable member of the two-component regulatory system ykoH/ykoG [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=36.8421052631579, Blast_Score=68, Evalue=1e-13,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=30.327868852459, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=31.1926605504587, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1788394, Length=124, Percent_Identity=29.8387096774194, Blast_Score=60, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=113, Percent_Identity=35.3982300884956, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI1786911, Length=113, Percent_Identity=36.283185840708, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13475; Mature: 13475

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEHPLVLVVDDDPDILDAICDILEGEGYRVARARHGLEALDRVAEEEPSIILLDLMMPV
CCCCCEEEEECCCCHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHCCCCCEEHHHHHHHH
MDGLAFAQALRQRRNGAARIPIVVISADGNPQKAASVGAQGYLAKPFDIDALLAQVTDMA
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
GQAMPG
CCCCCC
>Mature Secondary Structure
MNEHPLVLVVDDDPDILDAICDILEGEGYRVARARHGLEALDRVAEEEPSIILLDLMMPV
CCCCCEEEEECCCCHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHCCCCCEEHHHHHHHH
MDGLAFAQALRQRRNGAARIPIVVISADGNPQKAASVGAQGYLAKPFDIDALLAQVTDMA
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
GQAMPG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]