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The map label for this gene is nreC [H]

Identifier: 220917070

GI number: 220917070

Start: 2220363

End: 2221019

Strand: Direct

Name: nreC [H]

Synonym: A2cp1_1966

Alternate gene names: 220917070

Gene position: 2220363-2221019 (Clockwise)

Preceding gene: 220917069

Following gene: 220917073

Centisome position: 44.15

GC content: 70.62

Gene sequence:

>657_bases
GTGAGCGACAAGATCCGGGTGGTCATCGTGGACGACCACGCCATCCTGCGCGAGGGCGTGCGTGCGCTGCTCCAGCTCCA
GCCCGACATCGAGGTGGTCGGCGAGGGCGCCGACGGGATGCAGGCGCTGGAGCAGGTGGAGCGGCTCGATCCGGACGTGG
TGCTGATGGACATCGCCATGCCCGGGCTGGGCGGCATCGAGGCCAGCCTCCAGCTGAAGAAGCTGGGGCGGCGCGCGCGC
ATCCTGATCCTCTCGCAGTACGAGGATCGCGAGTACGTCCGCCGCCTGCTCAAGGCCGGCGTGTCGGGCTACGTGCTCAA
GAAGTCCGCCGGCGCCGAGCTCGCGAACGCCGTCCGCGCGGTCCACCGGGGAGGCCTGGTGCTCGACCCCGAGGTCGCGC
GCACCGCCATGGAGGAGGCCGGCCCGGCGGCGCCCGGCGAGGCGGATCCCTACGAGTCGCTCACCGACCGCGAGAAGCAG
GTGCTGAAGCTGGTGGCCGAGGGGCGGAGCAACAAGGAGGTGGCGGACGTCCTCGGCATCAGCGTGAAGACCGCCATGAG
CCACCGCGAGCACGTGATGGAGAAGCTCGGGGTCCACAACCGCACCGAGCTCGTCCGCTTCGCGATCCGCAAGGGCGTGA
TCCGCGTGGACGAGTAG

Upstream 100 bases:

>100_bases
AGGGCACCCGCGTCGAGGTGCGCATCCCGGTGCCGCGCGCCACGACCGAGCCGGGCCCCGCCGCCGCCGGAGCGGACGCG
GACGCCGAGGGGAGGGGAAC

Downstream 100 bases:

>100_bases
CGCGTCGCGGGCCGCAACGAAGAGATGCGGCGCAGCCGCCGGCCCCCACCGGAAGCTGCCCGCATCGGGTGAAGAACCGC
AGCCCCCCTCCCAGAGTGCT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSDKIRVVIVDDHAILREGVRALLQLQPDIEVVGEGADGMQALEQVERLDPDVVLMDIAMPGLGGIEASLQLKKLGRRAR
ILILSQYEDREYVRRLLKAGVSGYVLKKSAGAELANAVRAVHRGGLVLDPEVARTAMEEAGPAAPGEADPYESLTDREKQ
VLKLVAEGRSNKEVADVLGISVKTAMSHREHVMEKLGVHNRTELVRFAIRKGVIRVDE

Sequences:

>Translated_218_residues
MSDKIRVVIVDDHAILREGVRALLQLQPDIEVVGEGADGMQALEQVERLDPDVVLMDIAMPGLGGIEASLQLKKLGRRAR
ILILSQYEDREYVRRLLKAGVSGYVLKKSAGAELANAVRAVHRGGLVLDPEVARTAMEEAGPAAPGEADPYESLTDREKQ
VLKLVAEGRSNKEVADVLGISVKTAMSHREHVMEKLGVHNRTELVRFAIRKGVIRVDE
>Mature_217_residues
SDKIRVVIVDDHAILREGVRALLQLQPDIEVVGEGADGMQALEQVERLDPDVVLMDIAMPGLGGIEASLQLKKLGRRARI
LILSQYEDREYVRRLLKAGVSGYVLKKSAGAELANAVRAVHRGGLVLDPEVARTAMEEAGPAAPGEADPYESLTDREKQV
LKLVAEGRSNKEVADVLGISVKTAMSHREHVMEKLGVHNRTELVRFAIRKGVIRVDE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=197, Percent_Identity=40.6091370558376, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=32.2429906542056, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=38.6138613861386, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788712, Length=209, Percent_Identity=28.7081339712919, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=28.2178217821782, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=37.1584699453552, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=30.2884615384615, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082052, Length=114, Percent_Identity=35.0877192982456, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23884; Mature: 23753

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKIRVVIVDDHAILREGVRALLQLQPDIEVVGEGADGMQALEQVERLDPDVVLMDIAM
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEECC
PGLGGIEASLQLKKLGRRARILILSQYEDREYVRRLLKAGVSGYVLKKSAGAELANAVRA
CCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
VHRGGLVLDPEVARTAMEEAGPAAPGEADPYESLTDREKQVLKLVAEGRSNKEVADVLGI
HHHCCCEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SVKTAMSHREHVMEKLGVHNRTELVRFAIRKGVIRVDE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECC
>Mature Secondary Structure 
SDKIRVVIVDDHAILREGVRALLQLQPDIEVVGEGADGMQALEQVERLDPDVVLMDIAM
CCCEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCEEEEEECC
PGLGGIEASLQLKKLGRRARILILSQYEDREYVRRLLKAGVSGYVLKKSAGAELANAVRA
CCCCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHH
VHRGGLVLDPEVARTAMEEAGPAAPGEADPYESLTDREKQVLKLVAEGRSNKEVADVLGI
HHHCCCEECHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SVKTAMSHREHVMEKLGVHNRTELVRFAIRKGVIRVDE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]