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The map label for this gene is zraR [H]

Identifier: 220916929

GI number: 220916929

Start: 2038712

End: 2039722

Strand: Direct

Name: zraR [H]

Synonym: A2cp1_1825

Alternate gene names: 220916929

Gene position: 2038712-2039722 (Clockwise)

Preceding gene: 220916920

Following gene: 220916932

Centisome position: 40.54

GC content: 76.46

Gene sequence:

>1011_bases
ATGGAACGCCTTCCGGTCATGAGCGATGCGTGCGCGGTCTGCGGCCTGGGGACCGTGGTCGAGCGCGTCCGGCGCACCAC
GCACGTGGTGGCGGAGAGCCCGGCCATGCAGGCGGTGCTGGTGCGGGCGCGCGACTTCGCGGACGCCGATGCCCCGGTCG
TCATCCTGGGGGAGAGCGGGACGGGCAAGGAGGTGGTCGCCCGCGCGCTCCACGCGAGCGGCCCGCGGGGCGCCCGCCCG
TTCGTGGCGGTGAACGTGGCGGCGTTGCCTGGGGACCTGCTCGAGTCCGAGCTGTTCGGCCACGTGAAGGGCGCGTTCAC
CGGCGCGACCGCCGAGAAGCAGGGGCTGCTCGAGGCGGCGCACGGGGGCACGCTCTTCCTCGACGAGATCGGCGAGATGC
CGCTGCCGCTCCAGGCGAAGCTGCTGCGGGCGCTCGAGGACGGCGAGGTGCGCCGGGTGGGCGACACGCGCGCGTTCGGC
GTGGACGTCCGCTTCGTCTGCGCCACGCACCAGGACCTGGCGCGCCTGGTGACGGAGGGGCGCTTCCGCGAGGACCTCTA
CTACCGCCTGAAGGTGCTGGTGCTGCGCCTCCCGCCGCTCCGCGACCGCCCCGAGGACGTGCTGCCGCTGGCGCGCCGCT
TCCTCGCCGAGGAGAAGCGCCCGGGCCCGGGGTTCTCGCCCGAGGCCGAGCGGCGGCTCCTCGCCTACCGCTGGCCGGGG
AACGTGCGCGAGCTCGGCAACGTGGTCCGCTACGCGGCGGCGGTGGCGCGCGGGGCCGAGATCCGCCCCGAGCACCTGCC
GGAGGAGCTGACCGCGCCGGCCGGGCCCGCGGCGCGCGGCGGCACGGCGGGCGAGCCGGCGGCGATGGCCACGCTCGCCG
AGGTGGAGCGGGCGCACGTGCTCGCGGTGCTGGAGCGCTGCGGTGGCTCGCAGGCGGAGGCCGCGCGGGTGCTGGGCATC
GGCCGGAACACGCTCTGGCGGAAGCTGAAGGCGTACGACGGGCCGGCCTGA

Upstream 100 bases:

>100_bases
CAGAGCACGGGCCGTGCCGGATGCCGATCCCCCGGTTTCCGGGCCGGAATGCGCCGATGCGCGCCGCGGCGGGCCCGGTT
AAGCTCCAGCCTGGAACACC

Downstream 100 bases:

>100_bases
TCCGGCGCATCCCGACCCTTCGACTCCGGGCGCTCATCCCGACCCTTCGACTCCGAGCCGCTCATCCCGAGCGTAGGCCG
TGCCCCCTCGACTCCGGGCC

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MERLPVMSDACAVCGLGTVVERVRRTTHVVAESPAMQAVLVRARDFADADAPVVILGESGTGKEVVARALHASGPRGARP
FVAVNVAALPGDLLESELFGHVKGAFTGATAEKQGLLEAAHGGTLFLDEIGEMPLPLQAKLLRALEDGEVRRVGDTRAFG
VDVRFVCATHQDLARLVTEGRFREDLYYRLKVLVLRLPPLRDRPEDVLPLARRFLAEEKRPGPGFSPEAERRLLAYRWPG
NVRELGNVVRYAAAVARGAEIRPEHLPEELTAPAGPAARGGTAGEPAAMATLAEVERAHVLAVLERCGGSQAEAARVLGI
GRNTLWRKLKAYDGPA

Sequences:

>Translated_336_residues
MERLPVMSDACAVCGLGTVVERVRRTTHVVAESPAMQAVLVRARDFADADAPVVILGESGTGKEVVARALHASGPRGARP
FVAVNVAALPGDLLESELFGHVKGAFTGATAEKQGLLEAAHGGTLFLDEIGEMPLPLQAKLLRALEDGEVRRVGDTRAFG
VDVRFVCATHQDLARLVTEGRFREDLYYRLKVLVLRLPPLRDRPEDVLPLARRFLAEEKRPGPGFSPEAERRLLAYRWPG
NVRELGNVVRYAAAVARGAEIRPEHLPEELTAPAGPAARGGTAGEPAAMATLAEVERAHVLAVLERCGGSQAEAARVLGI
GRNTLWRKLKAYDGPA
>Mature_336_residues
MERLPVMSDACAVCGLGTVVERVRRTTHVVAESPAMQAVLVRARDFADADAPVVILGESGTGKEVVARALHASGPRGARP
FVAVNVAALPGDLLESELFGHVKGAFTGATAEKQGLLEAAHGGTLFLDEIGEMPLPLQAKLLRALEDGEVRRVGDTRAFG
VDVRFVCATHQDLARLVTEGRFREDLYYRLKVLVLRLPPLRDRPEDVLPLARRFLAEEKRPGPGFSPEAERRLLAYRWPG
NVRELGNVVRYAAAVARGAEIRPEHLPEELTAPAGPAARGGTAGEPAAMATLAEVERAHVLAVLERCGGSQAEAARVLGI
GRNTLWRKLKAYDGPA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=311, Percent_Identity=47.9099678456592, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=46.6666666666667, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1790437, Length=306, Percent_Identity=48.6928104575163, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1789233, Length=301, Percent_Identity=46.5116279069767, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1788905, Length=309, Percent_Identity=43.042071197411, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87082117, Length=315, Percent_Identity=43.1746031746032, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787583, Length=312, Percent_Identity=42.9487179487179, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1789087, Length=313, Percent_Identity=42.8115015974441, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=323, Percent_Identity=43.6532507739938, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=238, Percent_Identity=49.5798319327731, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=227, Percent_Identity=48.0176211453744, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87081858, Length=308, Percent_Identity=34.0909090909091, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789828, Length=319, Percent_Identity=33.8557993730408, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 36112; Mature: 36112

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLPVMSDACAVCGLGTVVERVRRTTHVVAESPAMQAVLVRARDFADADAPVVILGESG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCC
TGKEVVARALHASGPRGARPFVAVNVAALPGDLLESELFGHVKGAFTGATAEKQGLLEAA
CCHHHHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
HGGTLFLDEIGEMPLPLQAKLLRALEDGEVRRVGDTRAFGVDVRFVCATHQDLARLVTEG
CCCEEEHHHHCCCCCCHHHHHHHHHCCCCEEECCCCEEECCEEEEEECCHHHHHHHHHCC
RFREDLYYRLKVLVLRLPPLRDRPEDVLPLARRFLAEEKRPGPGFSPEAERRLLAYRWPG
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEECCC
NVRELGNVVRYAAAVARGAEIRPEHLPEELTAPAGPAARGGTAGEPAAMATLAEVERAHV
CHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAVLERCGGSQAEAARVLGIGRNTLWRKLKAYDGPA
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERLPVMSDACAVCGLGTVVERVRRTTHVVAESPAMQAVLVRARDFADADAPVVILGESG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCC
TGKEVVARALHASGPRGARPFVAVNVAALPGDLLESELFGHVKGAFTGATAEKQGLLEAA
CCHHHHHHHHHCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
HGGTLFLDEIGEMPLPLQAKLLRALEDGEVRRVGDTRAFGVDVRFVCATHQDLARLVTEG
CCCEEEHHHHCCCCCCHHHHHHHHHCCCCEEECCCCEEECCEEEEEECCHHHHHHHHHCC
RFREDLYYRLKVLVLRLPPLRDRPEDVLPLARRFLAEEKRPGPGFSPEAERRLLAYRWPG
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEECCC
NVRELGNVVRYAAAVARGAEIRPEHLPEELTAPAGPAARGGTAGEPAAMATLAEVERAHV
CHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LAVLERCGGSQAEAARVLGIGRNTLWRKLKAYDGPA
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]