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The map label for this gene is sasA [H]

Identifier: 220916620

GI number: 220916620

Start: 1694030

End: 1695163

Strand: Reverse

Name: sasA [H]

Synonym: A2cp1_1514

Alternate gene names: 220916620

Gene position: 1695163-1694030 (Counterclockwise)

Preceding gene: 220916621

Following gene: 220916617

Centisome position: 33.71

GC content: 70.72

Gene sequence:

>1134_bases
ATGCTACAAAGAGGCCCAGGGGGTGTCTCCGTGCTCCACGAGTTCCTGACCCAGCACCGCGACGCCATCATCGAGCGCGC
GCGGGCGAGGGTCGCCGCGAGGCGCGTACCCGTTCCTTCCCAGTTCGAGCTCACGGAAGGCGTCCCTGCGTTCCTCACCC
AGCTCGCCGAGCTGCTGCGCGACGAGGTGCATCCCGCACGATCCGTGACCGTACCGACGACGTCGGGACGTGCTCACGAG
GCGATGGGGGCCACCGCCGACCGGCAAGGGGACGACCTGCTCCGCGCAGGCTTGACCGTCGCGCAGGTGGTCGAAGGCTA
CGGCGACGTCTGCCAGGCGATCACGGAGTACGCCAGCGAGCTCAAGGCGCCGATCAGCCTGGACGAGTACCACACGCTCA
ACCTGTGCCTCGACGTGGCCACCGCCCGTGCGGTGAGCGCCTTCTCCGCCTCGCGCGACCGCCGCACGGCGACCCAGGAG
ACCGAGCGGCTCGGCGTGCTCGCGCACGAGATGCGAAACCTCCTGTCGACGGCGATGCTGTCCTACCAGGCGCTGAAGAG
CGGTGGAGTGGGCGTCGACGGCAGCACCGGCGCGGTGCTCGGGCGCAGCTTGCGCGGTCTGCGCAACCTCATCGACCGCT
CGCTGACCGAGGTTCGCCTGGCCGCCACGCTCCGGAACCCGGAGCGCGTCGATCTGGCCGAGTTCATCGAGGAGCTGGAG
GTGTCCGCCGCCCTCGACGCGACGGCGAAGGGGCTGGCGCTCGAGGTCCCTGCCGTCGAGCCGGGCGTGGCGGTGAACGT
CGACCGCCCGCTGCTTGCCTCGGCGGTCGCCAACCTCGTCCAGAACGCGATCAAGTTCACCCCCTCGGGCGGTCGTGTGT
CGCTCACCGGGCACCGGAACGCGACGCACGCCCTCATCGAGGTCGAGGACGAGTGCGGTGGGCTCCCCGAGGGCCGTGCC
GAGACGATGTTCCAACCGTTCGCCCGGGGAGGAACGGATGCGGGCCCCCCCGGCCTCGGCCTCGGGCTCAAGATCAGCCG
CGACGCCGTGCTGGCGAACGGCGGCCAGATCCAGGTTCGGAACCTTCCGGGCAAGGGCTGCGTGTTCAGCATCGCGCTGC
CGCCGGTCGAGTGA

Upstream 100 bases:

>100_bases
TGCTGATCGCGACCGATCGTTCCAGGGGATCGGGCGCCTCGTCGCTGGAGGGGCGGACCCACGGCCGCCCCCCAGCGCGC
CCGGACCTCGAGCGGACCTG

Downstream 100 bases:

>100_bases
GAACACGGTCTCGCTTCGGCTGACGCTACGGCAGCGCCGCTGCTGGCCCACTGCGTACGTTGCCCCGTGTCAAACGACAG
GGGGAATTGACCCCCAAACG

Product: histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLQRGPGGVSVLHEFLTQHRDAIIERARARVAARRVPVPSQFELTEGVPAFLTQLAELLRDEVHPARSVTVPTTSGRAHE
AMGATADRQGDDLLRAGLTVAQVVEGYGDVCQAITEYASELKAPISLDEYHTLNLCLDVATARAVSAFSASRDRRTATQE
TERLGVLAHEMRNLLSTAMLSYQALKSGGVGVDGSTGAVLGRSLRGLRNLIDRSLTEVRLAATLRNPERVDLAEFIEELE
VSAALDATAKGLALEVPAVEPGVAVNVDRPLLASAVANLVQNAIKFTPSGGRVSLTGHRNATHALIEVEDECGGLPEGRA
ETMFQPFARGGTDAGPPGLGLGLKISRDAVLANGGQIQVRNLPGKGCVFSIALPPVE

Sequences:

>Translated_377_residues
MLQRGPGGVSVLHEFLTQHRDAIIERARARVAARRVPVPSQFELTEGVPAFLTQLAELLRDEVHPARSVTVPTTSGRAHE
AMGATADRQGDDLLRAGLTVAQVVEGYGDVCQAITEYASELKAPISLDEYHTLNLCLDVATARAVSAFSASRDRRTATQE
TERLGVLAHEMRNLLSTAMLSYQALKSGGVGVDGSTGAVLGRSLRGLRNLIDRSLTEVRLAATLRNPERVDLAEFIEELE
VSAALDATAKGLALEVPAVEPGVAVNVDRPLLASAVANLVQNAIKFTPSGGRVSLTGHRNATHALIEVEDECGGLPEGRA
ETMFQPFARGGTDAGPPGLGLGLKISRDAVLANGGQIQVRNLPGKGCVFSIALPPVE
>Mature_377_residues
MLQRGPGGVSVLHEFLTQHRDAIIERARARVAARRVPVPSQFELTEGVPAFLTQLAELLRDEVHPARSVTVPTTSGRAHE
AMGATADRQGDDLLRAGLTVAQVVEGYGDVCQAITEYASELKAPISLDEYHTLNLCLDVATARAVSAFSASRDRRTATQE
TERLGVLAHEMRNLLSTAMLSYQALKSGGVGVDGSTGAVLGRSLRGLRNLIDRSLTEVRLAATLRNPERVDLAEFIEELE
VSAALDATAKGLALEVPAVEPGVAVNVDRPLLASAVANLVQNAIKFTPSGGRVSLTGHRNATHALIEVEDECGGLPEGRA
ETMFQPFARGGTDAGPPGLGLGLKISRDAVLANGGQIQVRNLPGKGCVFSIALPPVE

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=257, Percent_Identity=29.1828793774319, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=24.3027888446215, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=28.0334728033473, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=275, Percent_Identity=26.9090909090909, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=26.3392857142857, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 39864; Mature: 39864

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRGPGGVSVLHEFLTQHRDAIIERARARVAARRVPVPSQFELTEGVPAFLTQLAELLR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHH
DEVHPARSVTVPTTSGRAHEAMGATADRQGDDLLRAGLTVAQVVEGYGDVCQAITEYASE
HHCCCCCEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAPISLDEYHTLNLCLDVATARAVSAFSASRDRRTATQETERLGVLAHEMRNLLSTAML
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYQALKSGGVGVDGSTGAVLGRSLRGLRNLIDRSLTEVRLAATLRNPERVDLAEFIEELE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VSAALDATAKGLALEVPAVEPGVAVNVDRPLLASAVANLVQNAIKFTPSGGRVSLTGHRN
HHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCC
ATHALIEVEDECGGLPEGRAETMFQPFARGGTDAGPPGLGLGLKISRDAVLANGGQIQVR
CCEEEEEECHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEECCCEEEEE
NLPGKGCVFSIALPPVE
ECCCCCCEEEEECCCCC
>Mature Secondary Structure
MLQRGPGGVSVLHEFLTQHRDAIIERARARVAARRVPVPSQFELTEGVPAFLTQLAELLR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHH
DEVHPARSVTVPTTSGRAHEAMGATADRQGDDLLRAGLTVAQVVEGYGDVCQAITEYASE
HHCCCCCEEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAPISLDEYHTLNLCLDVATARAVSAFSASRDRRTATQETERLGVLAHEMRNLLSTAML
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYQALKSGGVGVDGSTGAVLGRSLRGLRNLIDRSLTEVRLAATLRNPERVDLAEFIEELE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VSAALDATAKGLALEVPAVEPGVAVNVDRPLLASAVANLVQNAIKFTPSGGRVSLTGHRN
HHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCC
ATHALIEVEDECGGLPEGRAETMFQPFARGGTDAGPPGLGLGLKISRDAVLANGGQIQVR
CCEEEEEECHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEECCCEEEEE
NLPGKGCVFSIALPPVE
ECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA