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The map label for this gene is polX [H]

Identifier: 220916495

GI number: 220916495

Start: 1554943

End: 1556721

Strand: Reverse

Name: polX [H]

Synonym: A2cp1_1389

Alternate gene names: 220916495

Gene position: 1556721-1554943 (Counterclockwise)

Preceding gene: 220916499

Following gene: 220916494

Centisome position: 30.95

GC content: 76.95

Gene sequence:

>1779_bases
ATGCCGGACAAGTTCGCCGTGGCGCAGGCGCTCCGGGAGATCGGCGCCCTGCTGGAGCTCGAGGGCGAGAACCCGTTCAA
GATCCGCGCGTACGACACCGGCGCGCGGGCGCTCGAGGGGCTCTCCGAGGACCTGGCGCGCGTGATCGCCGAGGGACGGC
TCACCGAGCTGCCCGGGATCGGCGAGGCGCTGGCGAAGAAGATCGCGGACCTGCACGCGACCGGCTCGACCGACCTGCTG
GCTCGGCTGCGGGCGCGCCACCCGCCCGGCGTCCTCGAGTTGCTGCGCGTGCCGGACCTCGGCCCGAAGAAGATCGCCGC
GCTGCACGCGGCGCTGGGCGTCGCGAGCGTCGCGGAGCTCGAGGCCGCCTGCCGCGAGGGGCGCGTCCGCGGCGTGAAGG
GGTTCGGCGAGAAGACCGAGCAGCGGATCCTGGAGGGCATCGCCCGCCTGCACGCGCGCGAGGCCGACCGGCGCGTGCTG
CTCGCCGAGGCGCTGACCGCCGCCGAGCCGCTGCTCGCGCACCTGCGCGCGGTGCCGGGGGCCGAGGCGGTGGAGCTGGC
CGGGTCGGCGCGCCGCGGCCGCGAGCTGGTGGGCGACGTCGACCTCGTCGCCGCGTCCCGGACGCCGGCCGCGCTCGCCG
CGGCGCTCACCGGCCATCCGCTGGTCGCGGCGGTGCTGGGGAGCGGCGACACGAAGACCAGCGTCCGGCTCGGCTCCGGG
CTGCAGGTCGACCTGCGGGTGGTGCCGCCGGAGGACTTCCCCACCCTGCTCCACCACCTCACCGGCTCGAAGGCGCACCA
CGTGCGGCTGCGCGGCATCGCCCGCGATCGCGGCTTCACGCTGAGCGAGTGGGGCCTGTTCCGCCTGCCGCCGCGCGAGC
GCGGGGCGGCCGCGCCGGCGGCGGAGGCGGCGCCCGATCCCGCCGCCAAGGTCCCGATCGCGAGCGAGGCCGCGCTCTAC
GCCGCGCTGGGCCTGGCGTACGTGCCGCCCGAGCTGCGCGAGGACCAGGGCGAGATCGAGGCCGCGCTGGACGGGACGCT
CCCGGCCGACCTGGTCGAGGCGCGCGACGTGCGCGGGATGGTGCACTGCCACACCACCTGGTCGGACGGCCGGGCGAGCG
TCGAGGAGATGGCCCGCGCCGCCGAGGCGCTCGGGATGGCGTACCTCACCGTCACCGACCACTCCGGCTCGGCCGGCTAC
GCCGGCGGGCTCGACCGCGACCGGATCCGGCGGCAGTGGGACGAGATCGACGGGGTGCAGGAGCGGGTCTCGATCCGGCT
GCTGAAGGGCACCGAGGCCGACATCCTCGAGGACGGCGCGCTCGACTGGCCCGACGACGTGCTGGAGCGGCTCGACGTGG
TGGTCGCGAGCGTCCACTCGCGGATGCGCATGGACGAGGACCAGATGACGCGCCGGCTCGCCCGCGCCATGGCGCTCCCG
GTGTTCAAGATCTGGGGGCACGGGCTGGGGCGGCTGCTGGGCGAGCGCGAGCCCTACGCCTGCCGCGTGGAGGAGGTCCT
CGACGCGCTGGCCGGCGCGCCGGGCGCGGTGGAGGTGAACGGGGATCCCCGCCGCCTCGACCTCGAGCCCCGCTGGATCC
GGGCGGCGCGCGCGCGCGGCATCCCGCTGGTCCTGTCGGTGGACGCCCACTCGGTCGCGGCGCTCGGCTACCTCCGCTTC
GCGGTGACCACCGCGCGGCGCGGCTGGGCGCGGCGCGGCGAGGTGCTGAACGCGCTGCCGGCGGACGCGTTCGCGCGGGC
GGTCCGTCCGGTGCGGTGA

Upstream 100 bases:

>100_bases
GCGGCGGCGTGCGAGGTGGCCCCCGCGCCGGCCGGCCGGGCCCGGGAGGGAGGTGTCGGGGTGCGGCTCCATGCGCGCCG
CGACGGTATATAAGCGCTCG

Downstream 100 bases:

>100_bases
CGCGGCGGCGGGCCGCCTCGCCGGGCGCTCGACGCGGGCGCCCATCTCGCCTACCTTCCCGGCTGCGTGCCGACCCAGCC
CACCACCCGCGAGGCCCTCC

Product: PHP domain-containing protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MPDKFAVAQALREIGALLELEGENPFKIRAYDTGARALEGLSEDLARVIAEGRLTELPGIGEALAKKIADLHATGSTDLL
ARLRARHPPGVLELLRVPDLGPKKIAALHAALGVASVAELEAACREGRVRGVKGFGEKTEQRILEGIARLHAREADRRVL
LAEALTAAEPLLAHLRAVPGAEAVELAGSARRGRELVGDVDLVAASRTPAALAAALTGHPLVAAVLGSGDTKTSVRLGSG
LQVDLRVVPPEDFPTLLHHLTGSKAHHVRLRGIARDRGFTLSEWGLFRLPPRERGAAAPAAEAAPDPAAKVPIASEAALY
AALGLAYVPPELREDQGEIEAALDGTLPADLVEARDVRGMVHCHTTWSDGRASVEEMARAAEALGMAYLTVTDHSGSAGY
AGGLDRDRIRRQWDEIDGVQERVSIRLLKGTEADILEDGALDWPDDVLERLDVVVASVHSRMRMDEDQMTRRLARAMALP
VFKIWGHGLGRLLGEREPYACRVEEVLDALAGAPGAVEVNGDPRRLDLEPRWIRAARARGIPLVLSVDAHSVAALGYLRF
AVTTARRGWARRGEVLNALPADAFARAVRPVR

Sequences:

>Translated_592_residues
MPDKFAVAQALREIGALLELEGENPFKIRAYDTGARALEGLSEDLARVIAEGRLTELPGIGEALAKKIADLHATGSTDLL
ARLRARHPPGVLELLRVPDLGPKKIAALHAALGVASVAELEAACREGRVRGVKGFGEKTEQRILEGIARLHAREADRRVL
LAEALTAAEPLLAHLRAVPGAEAVELAGSARRGRELVGDVDLVAASRTPAALAAALTGHPLVAAVLGSGDTKTSVRLGSG
LQVDLRVVPPEDFPTLLHHLTGSKAHHVRLRGIARDRGFTLSEWGLFRLPPRERGAAAPAAEAAPDPAAKVPIASEAALY
AALGLAYVPPELREDQGEIEAALDGTLPADLVEARDVRGMVHCHTTWSDGRASVEEMARAAEALGMAYLTVTDHSGSAGY
AGGLDRDRIRRQWDEIDGVQERVSIRLLKGTEADILEDGALDWPDDVLERLDVVVASVHSRMRMDEDQMTRRLARAMALP
VFKIWGHGLGRLLGEREPYACRVEEVLDALAGAPGAVEVNGDPRRLDLEPRWIRAARARGIPLVLSVDAHSVAALGYLRF
AVTTARRGWARRGEVLNALPADAFARAVRPVR
>Mature_591_residues
PDKFAVAQALREIGALLELEGENPFKIRAYDTGARALEGLSEDLARVIAEGRLTELPGIGEALAKKIADLHATGSTDLLA
RLRARHPPGVLELLRVPDLGPKKIAALHAALGVASVAELEAACREGRVRGVKGFGEKTEQRILEGIARLHAREADRRVLL
AEALTAAEPLLAHLRAVPGAEAVELAGSARRGRELVGDVDLVAASRTPAALAAALTGHPLVAAVLGSGDTKTSVRLGSGL
QVDLRVVPPEDFPTLLHHLTGSKAHHVRLRGIARDRGFTLSEWGLFRLPPRERGAAAPAAEAAPDPAAKVPIASEAALYA
ALGLAYVPPELREDQGEIEAALDGTLPADLVEARDVRGMVHCHTTWSDGRASVEEMARAAEALGMAYLTVTDHSGSAGYA
GGLDRDRIRRQWDEIDGVQERVSIRLLKGTEADILEDGALDWPDDVLERLDVVVASVHSRMRMDEDQMTRRLARAMALPV
FKIWGHGLGRLLGEREPYACRVEEVLDALAGAPGAVEVNGDPRRLDLEPRWIRAARARGIPLVLSVDAHSVAALGYLRFA
VTTARRGWARRGEVLNALPADAFARAVRPVR

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1796

COG function: function code L; DNA polymerase IV (family X)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63456; Mature: 63325

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDKFAVAQALREIGALLELEGENPFKIRAYDTGARALEGLSEDLARVIAEGRLTELPGI
CCCHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GEALAKKIADLHATGSTDLLARLRARHPPGVLELLRVPDLGPKKIAALHAALGVASVAEL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EAACREGRVRGVKGFGEKTEQRILEGIARLHAREADRRVLLAEALTAAEPLLAHLRAVPG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEAVELAGSARRGRELVGDVDLVAASRTPAALAAALTGHPLVAAVLGSGDTKTSVRLGSG
CHHHHHCCCHHHCHHHHCCHHEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEECCC
LQVDLRVVPPEDFPTLLHHLTGSKAHHVRLRGIARDRGFTLSEWGLFRLPPRERGAAAPA
CEEEEEEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEECCCCEEECCCHHCCCCCCC
AEAAPDPAAKVPIASEAALYAALGLAYVPPELREDQGEIEAALDGTLPADLVEARDVRGM
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHHHHHCCCE
VHCHTTWSDGRASVEEMARAAEALGMAYLTVTDHSGSAGYAGGLDRDRIRRQWDEIDGVQ
EEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ERVSIRLLKGTEADILEDGALDWPDDVLERLDVVVASVHSRMRMDEDQMTRRLARAMALP
HHHEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VFKIWGHGLGRLLGEREPYACRVEEVLDALAGAPGAVEVNGDPRRLDLEPRWIRAARARG
HHHHHHHHHHHHHCCCCCCEECHHHHHHHHHCCCCEEEECCCCCEECCCHHHHHHHHCCC
IPLVLSVDAHSVAALGYLRFAVTTARRGWARRGEVLNALPADAFARAVRPVR
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure 
PDKFAVAQALREIGALLELEGENPFKIRAYDTGARALEGLSEDLARVIAEGRLTELPGI
CCHHHHHHHHHHHHHHEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GEALAKKIADLHATGSTDLLARLRARHPPGVLELLRVPDLGPKKIAALHAALGVASVAEL
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EAACREGRVRGVKGFGEKTEQRILEGIARLHAREADRRVLLAEALTAAEPLLAHLRAVPG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AEAVELAGSARRGRELVGDVDLVAASRTPAALAAALTGHPLVAAVLGSGDTKTSVRLGSG
CHHHHHCCCHHHCHHHHCCHHEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEECCC
LQVDLRVVPPEDFPTLLHHLTGSKAHHVRLRGIARDRGFTLSEWGLFRLPPRERGAAAPA
CEEEEEEECCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEECCCCEEECCCHHCCCCCCC
AEAAPDPAAKVPIASEAALYAALGLAYVPPELREDQGEIEAALDGTLPADLVEARDVRGM
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHHHHHCCCE
VHCHTTWSDGRASVEEMARAAEALGMAYLTVTDHSGSAGYAGGLDRDRIRRQWDEIDGVQ
EEEEECCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
ERVSIRLLKGTEADILEDGALDWPDDVLERLDVVVASVHSRMRMDEDQMTRRLARAMALP
HHHEEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VFKIWGHGLGRLLGEREPYACRVEEVLDALAGAPGAVEVNGDPRRLDLEPRWIRAARARG
HHHHHHHHHHHHHCCCCCCEECHHHHHHHHHCCCCEEEECCCCCEECCCHHHHHHHHCCC
IPLVLSVDAHSVAALGYLRFAVTTARRGWARRGEVLNALPADAFARAVRPVR
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]