Click here to switch to the map view.

The map label for this gene is gph1 [H]

Identifier: 220916351

GI number: 220916351

Start: 1396059

End: 1396688

Strand: Reverse

Name: gph1 [H]

Synonym: A2cp1_1245

Alternate gene names: 220916351

Gene position: 1396688-1396059 (Counterclockwise)

Preceding gene: 220916352

Following gene: 220916350

Centisome position: 27.77

GC content: 77.78

Gene sequence:

>630_bases
ATGCCGCGCCTCGCCATCCTCGATCTCGACGGCACGCTGGTCGACTCGCTCGACGACCTCGCCGCCTCGGTGAACCACGC
GCTCGCCACGGTGGGCCTGCCGCCGCGCACGACGGACGAGATCCGCGGCTTCGTGGGCGAGGGCGCGCGGGTGCTCCTCG
AGCGCGCGCTCGGCCCGCACGCGGAGCGGCTCGAGCCGGCGCTCGCGGCCTGGCGCGCGCACTACGAGGTCCACTGCCTC
GACGCCACCCGCACGTACCCCGGGCTCGCCGCGGCGCTCGCCGGGGCCGGCCGCACGCTGGCGGTGCACACCAACAAGCC
CGGCGCGATGGCCCGCCGGATCCTCGACGGGCTCGGGCTGCTGGGCCGCTTCGCGGTGGTGGTCGGCGGGGACGAGGCGC
CGCGCAAGCCGGACCCGGAGGGCGTCCGCATCATCCAGTCGCGCGTGGGCGCCACCGACGCCGAGACGGTGTTCGTGGGG
GACAGCCCGGTGGACGTCGCGACGGCCCGCGCCGCGGGGGTGCAGATGGTCGCGGTGGGCTGGGGCCTGCGCAGCCGCGC
CGCGCTCCTCGACGCGGGCGCGACGGTGCTGGTCGAGAGCGCCGCGGAGCTGGTCCCGTGGCTCGCGTGA

Upstream 100 bases:

>100_bases
CGCGCTGCTCGCGGTGCTCCGCCGCCGTGGCGCGCTCCCGCCCGCCGGGAGCGCCGAGAGCGCCGCGTGAGCGCGGGGCG
GGTGTAGACTCGCCGCCGCC

Downstream 100 bases:

>100_bases
GGGCGGCGGCGCGGTCGCGCGGCGGCGCCGCCCGGACCGCGCGGCGGGGCTCCGAAAACTCGCCGCGACCCCGCGGCCGT
GCTACCCGGAGTCCCATGCT

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 1; PGPase 1 [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MPRLAILDLDGTLVDSLDDLAASVNHALATVGLPPRTTDEIRGFVGEGARVLLERALGPHAERLEPALAAWRAHYEVHCL
DATRTYPGLAAALAGAGRTLAVHTNKPGAMARRILDGLGLLGRFAVVVGGDEAPRKPDPEGVRIIQSRVGATDAETVFVG
DSPVDVATARAAGVQMVAVGWGLRSRAALLDAGATVLVESAAELVPWLA

Sequences:

>Translated_209_residues
MPRLAILDLDGTLVDSLDDLAASVNHALATVGLPPRTTDEIRGFVGEGARVLLERALGPHAERLEPALAAWRAHYEVHCL
DATRTYPGLAAALAGAGRTLAVHTNKPGAMARRILDGLGLLGRFAVVVGGDEAPRKPDPEGVRIIQSRVGATDAETVFVG
DSPVDVATARAAGVQMVAVGWGLRSRAALLDAGATVLVESAAELVPWLA
>Mature_208_residues
PRLAILDLDGTLVDSLDDLAASVNHALATVGLPPRTTDEIRGFVGEGARVLLERALGPHAERLEPALAAWRAHYEVHCLD
ATRTYPGLAAALAGAGRTLAVHTNKPGAMARRILDGLGLLGRFAVVVGGDEAPRKPDPEGVRIIQSRVGATDAETVFVGD
SPVDVATARAAGVQMVAVGWGLRSRAALLDAGATVLVESAAELVPWLA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=228, Percent_Identity=31.140350877193, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 21699; Mature: 21568

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLAILDLDGTLVDSLDDLAASVNHALATVGLPPRTTDEIRGFVGEGARVLLERALGPH
CCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC
AERLEPALAAWRAHYEVHCLDATRTYPGLAAALAGAGRTLAVHTNKPGAMARRILDGLGL
HHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
LGRFAVVVGGDEAPRKPDPEGVRIIQSRVGATDAETVFVGDSPVDVATARAAGVQMVAVG
HHHEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCEEEEEEC
WGLRSRAALLDAGATVLVESAAELVPWLA
CCCHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRLAILDLDGTLVDSLDDLAASVNHALATVGLPPRTTDEIRGFVGEGARVLLERALGPH
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC
AERLEPALAAWRAHYEVHCLDATRTYPGLAAALAGAGRTLAVHTNKPGAMARRILDGLGL
HHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
LGRFAVVVGGDEAPRKPDPEGVRIIQSRVGATDAETVFVGDSPVDVATARAAGVQMVAVG
HHHEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCEEEEEEC
WGLRSRAALLDAGATVLVESAAELVPWLA
CCCHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]