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The map label for this gene is ykoU [H]

Identifier: 220915950

GI number: 220915950

Start: 936643

End: 938694

Strand: Reverse

Name: ykoU [H]

Synonym: A2cp1_0836

Alternate gene names: 220915950

Gene position: 938694-936643 (Counterclockwise)

Preceding gene: 220915951

Following gene: 220915949

Centisome position: 18.66

GC content: 78.56

Gene sequence:

>2052_bases
ATGCCGGCCTGCCCCGCCGGCGCCCGCCGGGGGCGCCGCTTGCCCCGCCACGCCGGGGGTGGTGAGCTTTCCCGCGTGGC
CCGCGCGCCCGTCCCGATCTACCGCGCCCAGCTCGCGACGCTCGTCGCGACCCCGCCGGCGGGGGACGGCTGGGTCCACG
AGACGAAGTACGACGGCTACCGGATCGGCTGTTCGCTGGAGGGCGGGCGCGCCACGCTGTGGAGCCGGCGGGGCAACGAC
TGGACCGCGCAGTTCCCCGAGGTGGCGCAGGCCGCCGAGGCGCTGGCGGCGCGGAGCGCGCTCCTCGACGGCGAGGTGGC
GGCGGTGCTGCCCGGCGGCCGGACCAGCTTCCAGGCGCTCCAGCAGGCGTTCTCCGGGGGCCGCCGCTCGCTCGCCTACT
TCGTGTTCGACCTGCTCTGGCTGGACGGCGAGGACCTGTCCGGGCGGCCGCTGCTCGAGCGCAAGGACGCGCTGCGCCGG
CTCCTCGGCGCGCGCGGCGCCGTGCTCCGGTACGCGCCGCACGTGGAGGCGCCGGGCGCCGAGGTGCTCCGCGAGGCGTG
CCGCCTCGGCCTGGAGGGGATCGTCTCGAAGCGCGCCGACGCGCCGTACCGCCCCGGGCGGAACACCACCTGGACGAAGG
CGAAGTGCCTCGCCCGCCAGGAGCTGGTGATCGGCGGGTTCACCGATCCCGAGGGCAGCCGCCAGGGCATCGGGGCGCTG
CTGGTGGGCTTCCACGAGGGCGGCGCGCTGCGCTTCGCCGGGAAGGTCGGCACCGGCTTCACGCAGGCGTCGGCGCGGGC
GCTGCGCGCGCGCCTCGATCGCCTGGGCCGCGCCGACCCGCCGTTCACGCCCCGGCCGCCGGGCGCGCTCGGGCGGATCG
CGCACTGGGTGCGGCCGGAGCTGGTGGCCGAGGTGGCGTTCACCGAGTGGACCGACGACGGGAAGGTGCGGCATCCGTCG
TTCCAGGGGCTGCGCGAGGACAAGCGCGCCGCGGACGTGGTGCGCGAGGTCCCCGGCGGCGCGCCACCGGCCCCGCCGGT
CCCACCGGCGCCTGCGCCTGCGCCGGCGGCCGCGGGTCGCGCCAGGCGCCGCGCGGCGGCGGGCGCAGCCGGCGAGGTGG
TGATCGGCGGCGTCCGGCTCTCGCACCCGGAGCGCACCGTGTTCCCGGGCGACGGGCGGGCCGCGCTCACCAAGGCCGAC
GTGGCCCGGTACTACGACGCGGTGGCCGGCGCGATGGTGCCGCACCTGCGCGGCCGCCCGCTGACCCTGTTCCACTGCCC
GGAGGGCATCGCCGGCGAGTGCCGCTTCATGAAGCACTCGAAGACCTGGGCGCCGCCCGCCGTGCGGCGGGTGCGCATCC
AGGAGAAGACCAAGCTGGGCGAGTACCTGATCGCCGACGACCGCGCCGCGCTGCTCGCGCTGGTGCAGATGGACGTCCTC
GAGCTGCACACCTGGAACTCGACCGTGGAGGCGCTGGAGCAGCCGGACCGGATCGTGCTCGACCTCGACCCGGGGCCGGA
GGTCCCGTGGCGCGAGGTGGTGCGCGCGGCGCGGCTGCTGCGCTCGGCGCTGGAGGCGCTGGGCCTCGCCGCGTTCGTGA
AGACCACCGGCGGCGCGGGGCTGCACGTGGTGACGCCGCTGGTGCCGCGCCGGCGCTGGGAGGACTGCCTCGCGTTCGCG
CGCGGGCTCGCCGCCACGGTGGCGCGCCACGAGCCGCGCGCGTTCACCGTGGCGCTCGCGCGCGCCGGGCGCGAGCGGAA
GATCCTCCTCGACTACCTGCGGAACAACCGGACCAACACCTCGGTGGCCGCGTTCTCGCTGCGCGCGCGGCCGGGCGCGC
CGGCCTCGGTGCCGGTGGCCTGGGACGAGCTGGGCCCGCGGCTGCGGCCGGAGCGGCTGGACGCGCGCACCGTCCCGCGG
CGGCTGGCGCGGCTCGGCGCGGATCCGTGGGCCGGCTGGGCGCGCGCCGCCCGGCCGCTCGGCGACGCGCACCTCGCCGC
GGTGGGCGCCGCGCCGGTGGACCAGCCGGCGCGGGGCGGGGGGCGGCGGTGA

Upstream 100 bases:

>100_bases
CGACCAGCCGGTCATGCCTCAGCTCGGGCTGGCGCTCATCGCCATCACCTACCTCAGCCCGGTCGACGGCTGACGCTCCG
CCGCGGCGGCGCGCCCCTGG

Downstream 100 bases:

>100_bases
TCCGGGTCGGGACGAGCGGCTTCCAGTACCGCCACTGGCGCGGCGTGCTCTACCCGGACGACCTCCCCGCCCGCGCCTGG
CTCCCGCGCTACGCCGCCCT

Product: DNA ligase D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MPACPAGARRGRRLPRHAGGGELSRVARAPVPIYRAQLATLVATPPAGDGWVHETKYDGYRIGCSLEGGRATLWSRRGND
WTAQFPEVAQAAEALAARSALLDGEVAAVLPGGRTSFQALQQAFSGGRRSLAYFVFDLLWLDGEDLSGRPLLERKDALRR
LLGARGAVLRYAPHVEAPGAEVLREACRLGLEGIVSKRADAPYRPGRNTTWTKAKCLARQELVIGGFTDPEGSRQGIGAL
LVGFHEGGALRFAGKVGTGFTQASARALRARLDRLGRADPPFTPRPPGALGRIAHWVRPELVAEVAFTEWTDDGKVRHPS
FQGLREDKRAADVVREVPGGAPPAPPVPPAPAPAPAAAGRARRRAAAGAAGEVVIGGVRLSHPERTVFPGDGRAALTKAD
VARYYDAVAGAMVPHLRGRPLTLFHCPEGIAGECRFMKHSKTWAPPAVRRVRIQEKTKLGEYLIADDRAALLALVQMDVL
ELHTWNSTVEALEQPDRIVLDLDPGPEVPWREVVRAARLLRSALEALGLAAFVKTTGGAGLHVVTPLVPRRRWEDCLAFA
RGLAATVARHEPRAFTVALARAGRERKILLDYLRNNRTNTSVAAFSLRARPGAPASVPVAWDELGPRLRPERLDARTVPR
RLARLGADPWAGWARAARPLGDAHLAAVGAAPVDQPARGGGRR

Sequences:

>Translated_683_residues
MPACPAGARRGRRLPRHAGGGELSRVARAPVPIYRAQLATLVATPPAGDGWVHETKYDGYRIGCSLEGGRATLWSRRGND
WTAQFPEVAQAAEALAARSALLDGEVAAVLPGGRTSFQALQQAFSGGRRSLAYFVFDLLWLDGEDLSGRPLLERKDALRR
LLGARGAVLRYAPHVEAPGAEVLREACRLGLEGIVSKRADAPYRPGRNTTWTKAKCLARQELVIGGFTDPEGSRQGIGAL
LVGFHEGGALRFAGKVGTGFTQASARALRARLDRLGRADPPFTPRPPGALGRIAHWVRPELVAEVAFTEWTDDGKVRHPS
FQGLREDKRAADVVREVPGGAPPAPPVPPAPAPAPAAAGRARRRAAAGAAGEVVIGGVRLSHPERTVFPGDGRAALTKAD
VARYYDAVAGAMVPHLRGRPLTLFHCPEGIAGECRFMKHSKTWAPPAVRRVRIQEKTKLGEYLIADDRAALLALVQMDVL
ELHTWNSTVEALEQPDRIVLDLDPGPEVPWREVVRAARLLRSALEALGLAAFVKTTGGAGLHVVTPLVPRRRWEDCLAFA
RGLAATVARHEPRAFTVALARAGRERKILLDYLRNNRTNTSVAAFSLRARPGAPASVPVAWDELGPRLRPERLDARTVPR
RLARLGADPWAGWARAARPLGDAHLAAVGAAPVDQPARGGGRR
>Mature_682_residues
PACPAGARRGRRLPRHAGGGELSRVARAPVPIYRAQLATLVATPPAGDGWVHETKYDGYRIGCSLEGGRATLWSRRGNDW
TAQFPEVAQAAEALAARSALLDGEVAAVLPGGRTSFQALQQAFSGGRRSLAYFVFDLLWLDGEDLSGRPLLERKDALRRL
LGARGAVLRYAPHVEAPGAEVLREACRLGLEGIVSKRADAPYRPGRNTTWTKAKCLARQELVIGGFTDPEGSRQGIGALL
VGFHEGGALRFAGKVGTGFTQASARALRARLDRLGRADPPFTPRPPGALGRIAHWVRPELVAEVAFTEWTDDGKVRHPSF
QGLREDKRAADVVREVPGGAPPAPPVPPAPAPAPAAAGRARRRAAAGAAGEVVIGGVRLSHPERTVFPGDGRAALTKADV
ARYYDAVAGAMVPHLRGRPLTLFHCPEGIAGECRFMKHSKTWAPPAVRRVRIQEKTKLGEYLIADDRAALLALVQMDVLE
LHTWNSTVEALEQPDRIVLDLDPGPEVPWREVVRAARLLRSALEALGLAAFVKTTGGAGLHVVTPLVPRRRWEDCLAFAR
GLAATVARHEPRAFTVALARAGRERKILLDYLRNNRTNTSVAAFSLRARPGAPASVPVAWDELGPRLRPERLDARTVPRR
LARLGADPWAGWARAARPLGDAHLAAVGAAPVDQPARGGGRR

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 73440; Mature: 73309

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACPAGARRGRRLPRHAGGGELSRVARAPVPIYRAQLATLVATPPAGDGWVHETKYDGY
CCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHEECCCCCCCCEECCCCCCE
RIGCSLEGGRATLWSRRGNDWTAQFPEVAQAAEALAARSALLDGEVAAVLPGGRTSFQAL
EEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
QQAFSGGRRSLAYFVFDLLWLDGEDLSGRPLLERKDALRRLLGARGAVLRYAPHVEAPGA
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHH
EVLREACRLGLEGIVSKRADAPYRPGRNTTWTKAKCLARQELVIGGFTDPEGSRQGIGAL
HHHHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCEEE
LVGFHEGGALRFAGKVGTGFTQASARALRARLDRLGRADPPFTPRPPGALGRIAHWVRPE
EEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LVAEVAFTEWTDDGKVRHPSFQGLREDKRAADVVREVPGGAPPAPPVPPAPAPAPAAAGR
HHHHHHHHEECCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ARRRAAAGAAGEVVIGGVRLSHPERTVFPGDGRAALTKADVARYYDAVAGAMVPHLRGRP
HHHHHHCCCCCCEEEECEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTLFHCPEGIAGECRFMKHSKTWAPPAVRRVRIQEKTKLGEYLIADDRAALLALVQMDVL
EEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
ELHTWNSTVEALEQPDRIVLDLDPGPEVPWREVVRAARLLRSALEALGLAAFVKTTGGAG
HHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LHVVTPLVPRRRWEDCLAFARGLAATVARHEPRAFTVALARAGRERKILLDYLRNNRTNT
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHCCCCCC
SVAAFSLRARPGAPASVPVAWDELGPRLRPERLDARTVPRRLARLGADPWAGWARAARPL
EEEEEEEECCCCCCCCCCEEHHHHCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHCCC
GDAHLAAVGAAPVDQPARGGGRR
CCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PACPAGARRGRRLPRHAGGGELSRVARAPVPIYRAQLATLVATPPAGDGWVHETKYDGY
CCCCCCHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHEECCCCCCCCEECCCCCCE
RIGCSLEGGRATLWSRRGNDWTAQFPEVAQAAEALAARSALLDGEVAAVLPGGRTSFQAL
EEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
QQAFSGGRRSLAYFVFDLLWLDGEDLSGRPLLERKDALRRLLGARGAVLRYAPHVEAPGA
HHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCHH
EVLREACRLGLEGIVSKRADAPYRPGRNTTWTKAKCLARQELVIGGFTDPEGSRQGIGAL
HHHHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCEEE
LVGFHEGGALRFAGKVGTGFTQASARALRARLDRLGRADPPFTPRPPGALGRIAHWVRPE
EEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LVAEVAFTEWTDDGKVRHPSFQGLREDKRAADVVREVPGGAPPAPPVPPAPAPAPAAAGR
HHHHHHHHEECCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ARRRAAAGAAGEVVIGGVRLSHPERTVFPGDGRAALTKADVARYYDAVAGAMVPHLRGRP
HHHHHHCCCCCCEEEECEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTLFHCPEGIAGECRFMKHSKTWAPPAVRRVRIQEKTKLGEYLIADDRAALLALVQMDVL
EEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
ELHTWNSTVEALEQPDRIVLDLDPGPEVPWREVVRAARLLRSALEALGLAAFVKTTGGAG
HHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LHVVTPLVPRRRWEDCLAFARGLAATVARHEPRAFTVALARAGRERKILLDYLRNNRTNT
EEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHCCCCCC
SVAAFSLRARPGAPASVPVAWDELGPRLRPERLDARTVPRRLARLGADPWAGWARAARPL
EEEEEEEECCCCCCCCCCEEHHHHCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHCCC
GDAHLAAVGAAPVDQPARGGGRR
CCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]