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The map label for this gene is pgaC [H]

Identifier: 220915914

GI number: 220915914

Start: 900748

End: 901980

Strand: Reverse

Name: pgaC [H]

Synonym: A2cp1_0800

Alternate gene names: 220915914

Gene position: 901980-900748 (Counterclockwise)

Preceding gene: 220915915

Following gene: 220915913

Centisome position: 17.93

GC content: 80.62

Gene sequence:

>1233_bases
GTGAGCGCGCTCGTGCTCGCGCTCGTGGCGCTGGCGCTCGCGGGGTGGGCGCGGGTGGCGTGGAGCGGTCTCCGCAGCGA
TCGCGCGCTGGCCCGGCTCGAGGACCTCCCCGCGCCGCGCGTGGTGCCGCGCGTCTCGGTGGTCGTGCCGTGCCGCGACG
AGGCCCCGCACGTCGAGCGGGCGGTGCGCTCGCTGCTGGCGCAGGACCTGGCCGGCCTCGAGGTGGTGGCGGTGGACGAC
CGCTCCCGCGACGAGACCGGCGCCATCCTCGACCGGCTCGCCGCCGCCGAGCCCCGCCTCGCGGTCGTGCACGTGGGCGA
GCTGCCCGCCGGCTGGCTGGGGAAGAACCACGCCTGCGCCGCCGGGGCGCGGCGCGCGCGGGGCGAGTGGCTGCTGTTCA
CCGACGGCGACGTGGTGCTCGGACCGGGGGCGCTGCGCCGGGCCGTCGGCCACGCCGAGGCGCTCGGGCTCGGCCACCTC
GCCGCGGTGCCGCGCTTCGTCGCCCCCGGGGCGCTGGAGCGCGCGTTCGTGGCGGCGTTCGCCGCGTTCGCGGCCGGGGC
GTTCCGCGCCTGGGAGCTGCCGCGCGCCGGGACGCGCGGGTTCGCCGGGGTGGGCGCGTTCAACCTGGTCCGCCGCGACG
CGTACGAGGCGGTGGGCGGGCACGCGCGGCTGCGGCTCGAGGTGGTGGACGACGTGAAGCTCGGGCTCCTGCTGCGCCGC
AGCGGCGTGCCGCAGGGGCTGGTGAACGGCGGCCCGCTCGTGTCGGTCCGCTGGCAGCACGGCTTCGTCCCGTCGGTGCT
CGGGCTGGTGAAGAACGCGTTCGCCGGCGCGGAGTACCGGGTGGCCCGAGCGCTGGGCGTGGCGCTCTGGGCCCTGTTCC
TGGGCGCGGCGCCCCTCGCCCTCGCGCTCGCCGCGCAGGGCGGCGCGGCCCGGGCGCTCGGCGGGCTCGCGCTCGCCGTG
TCGGTGGGCGTGCTCGGCGTCACCGCCCGCCGGGTGGCGGGCGGGGGCGGCGCCGAGGGGCTGCTCATGCCGCCCTGCAC
CGTGCTGCTCGGGGTCGTGCTGCTCGCCAGCGCCGCCGCGGCCGCGTGGCGCGGCGGCGTGGTGTGGCGCGGCACGTTCT
ACCCGCTCCCGGCGCTGCGGAAGGGCTGCCTGCGGCGCGCGGACCTCCCTGCGGCGGGCGCGGCCGGCTGGCCGCACGCC
CCGGCCGAGCGGGCGCGGCGGAGCGCGCCCTGA

Upstream 100 bases:

>100_bases
GGCTGCTCGACCTCGACGACCTCCCTGCCGCCGCCGCGCGCGCCGGGTCCCGCGCGCCGGCGGCGGATGCCGGGCCGGCC
CCGGAGGGCGGGCCCGCCGC

Downstream 100 bases:

>100_bases
CGCCGCTTCGGTGATAGGTTTCGCGCGAATGCTCGGCCCGACCCTCTACACCGAGGTGCCCGTCCTCGCCGCCTGGGACG
AGACGGCGCCGTTCCGCGGC

Product: family 2 glycosyl transferase

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSALVLALVALALAGWARVAWSGLRSDRALARLEDLPAPRVVPRVSVVVPCRDEAPHVERAVRSLLAQDLAGLEVVAVDD
RSRDETGAILDRLAAAEPRLAVVHVGELPAGWLGKNHACAAGARRARGEWLLFTDGDVVLGPGALRRAVGHAEALGLGHL
AAVPRFVAPGALERAFVAAFAAFAAGAFRAWELPRAGTRGFAGVGAFNLVRRDAYEAVGGHARLRLEVVDDVKLGLLLRR
SGVPQGLVNGGPLVSVRWQHGFVPSVLGLVKNAFAGAEYRVARALGVALWALFLGAAPLALALAAQGGAARALGGLALAV
SVGVLGVTARRVAGGGGAEGLLMPPCTVLLGVVLLASAAAAAWRGGVVWRGTFYPLPALRKGCLRRADLPAAGAAGWPHA
PAERARRSAP

Sequences:

>Translated_410_residues
MSALVLALVALALAGWARVAWSGLRSDRALARLEDLPAPRVVPRVSVVVPCRDEAPHVERAVRSLLAQDLAGLEVVAVDD
RSRDETGAILDRLAAAEPRLAVVHVGELPAGWLGKNHACAAGARRARGEWLLFTDGDVVLGPGALRRAVGHAEALGLGHL
AAVPRFVAPGALERAFVAAFAAFAAGAFRAWELPRAGTRGFAGVGAFNLVRRDAYEAVGGHARLRLEVVDDVKLGLLLRR
SGVPQGLVNGGPLVSVRWQHGFVPSVLGLVKNAFAGAEYRVARALGVALWALFLGAAPLALALAAQGGAARALGGLALAV
SVGVLGVTARRVAGGGGAEGLLMPPCTVLLGVVLLASAAAAAWRGGVVWRGTFYPLPALRKGCLRRADLPAAGAAGWPHA
PAERARRSAP
>Mature_409_residues
SALVLALVALALAGWARVAWSGLRSDRALARLEDLPAPRVVPRVSVVVPCRDEAPHVERAVRSLLAQDLAGLEVVAVDDR
SRDETGAILDRLAAAEPRLAVVHVGELPAGWLGKNHACAAGARRARGEWLLFTDGDVVLGPGALRRAVGHAEALGLGHLA
AVPRFVAPGALERAFVAAFAAFAAGAFRAWELPRAGTRGFAGVGAFNLVRRDAYEAVGGHARLRLEVVDDVKLGLLLRRS
GVPQGLVNGGPLVSVRWQHGFVPSVLGLVKNAFAGAEYRVARALGVALWALFLGAAPLALALAAQGGAARALGGLALAVS
VGVLGVTARRVAGGGGAEGLLMPPCTVLLGVVLLASAAAAAWRGGVVWRGTFYPLPALRKGCLRRADLPAAGAAGWPHAP
AERARRSAP

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=113, Percent_Identity=40.7079646017699, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 42239; Mature: 42107

Theoretical pI: Translated: 11.67; Mature: 11.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALVLALVALALAGWARVAWSGLRSDRALARLEDLPAPRVVPRVSVVVPCRDEAPHVER
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHH
AVRSLLAQDLAGLEVVAVDDRSRDETGAILDRLAAAEPRLAVVHVGELPAGWLGKNHACA
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHH
AGARRARGEWLLFTDGDVVLGPGALRRAVGHAEALGLGHLAAVPRFVAPGALERAFVAAF
HHHHHCCCCEEEEECCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
AAFAAGAFRAWELPRAGTRGFAGVGAFNLVRRDAYEAVGGHARLRLEVVDDVKLGLLLRR
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHH
SGVPQGLVNGGPLVSVRWQHGFVPSVLGLVKNAFAGAEYRVARALGVALWALFLGAAPLA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LALAAQGGAARALGGLALAVSVGVLGVTARRVAGGGGAEGLLMPPCTVLLGVVLLASAAA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AAWRGGVVWRGTFYPLPALRKGCLRRADLPAAGAAGWPHAPAERARRSAP
HHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SALVLALVALALAGWARVAWSGLRSDRALARLEDLPAPRVVPRVSVVVPCRDEAPHVER
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHH
AVRSLLAQDLAGLEVVAVDDRSRDETGAILDRLAAAEPRLAVVHVGELPAGWLGKNHACA
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHH
AGARRARGEWLLFTDGDVVLGPGALRRAVGHAEALGLGHLAAVPRFVAPGALERAFVAAF
HHHHHCCCCEEEEECCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
AAFAAGAFRAWELPRAGTRGFAGVGAFNLVRRDAYEAVGGHARLRLEVVDDVKLGLLLRR
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHH
SGVPQGLVNGGPLVSVRWQHGFVPSVLGLVKNAFAGAEYRVARALGVALWALFLGAAPLA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LALAAQGGAARALGGLALAVSVGVLGVTARRVAGGGGAEGLLMPPCTVLLGVVLLASAAA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AAWRGGVVWRGTFYPLPALRKGCLRRADLPAAGAAGWPHAPAERARRSAP
HHHCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]