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The map label for this gene is tolQ [H]

Identifier: 220915814

GI number: 220915814

Start: 781284

End: 782057

Strand: Reverse

Name: tolQ [H]

Synonym: A2cp1_0697

Alternate gene names: 220915814

Gene position: 782057-781284 (Counterclockwise)

Preceding gene: 220915823

Following gene: 220915813

Centisome position: 15.55

GC content: 68.48

Gene sequence:

>774_bases
ATGCTAGAGAACCCCTTTCCCGACCTGCACATGACCGAACTCGCCCTCTCGCAGCTCCTGCCCTCCGCCGGCGTGCCCCT
CGCGGCCGCGGGCGGCCTCAACTACCTCGAGATCGCCACCAACTCCGGGCCCGTCGGCATCGGCGTGCTGGCGCTCCTGC
TCGGCGCCTCCGCGGTGTCGTGGGCCATCATCGTCAAGAAGTGGCTCCAGATCCGGCGCGCGCAGGACCAGTCGGTGAAG
TTCCTCGAGACCTTCTGGCAGTCCAAGCGGCTCGACGCCATCTACCAGGCGGCGGAGTCGCTGGGCGCGTCGCCGCTGTC
GCACGTGTTCCGGGCGGGCTACGTCGAGCTCTCGAAGGTGACGGCGCGCAAGAACGAGGGCGACCCGGGCGCCATGAGCG
ACCAGCTCGGCGGCATCGAGAACGTCGAGCGCGCGCTGAAGCGGGCCGCGGCCTCGGAGGTCACCGCGCTCGAGCGCCAG
GTGCCGTTCCTGGGCACCACCGCCAGCGCCGCCCCGTTCGTCGGCCTGTTCGGCACGGTGTGGGGCATCATGCGCGCGTT
CCACGAGATCTACCTGATGGGCAACGCGAACCTGGCCACGGTGGCGAAGCCCATCTCCGAGGCGCTCATCGCCACCGCGG
TCGGCCTGTTCGCCGCCATCCCGGCGGTGGTCGCCTACAACTTCTTCCTGTCGAAGATCCGCGTGCTCGACAGCGAGATG
ACCAACTTCTCGAACGACTTCCTGAACATCGTTCGGCGGCACTTCTTCAGCTAG

Upstream 100 bases:

>100_bases
CTCGGGAGGGGAAACGGCCCGCCGGGCGTTTACTGTCGAGCGCCCCGGATCCCGAGGAGAATGGGGGGTCGGGGAGAGGC
GCAGCCGAGCGGGCGCGTCC

Downstream 100 bases:

>100_bases
GGAGCGAGCCGTGGCGATGTCCTCCGGCGGCTCGGGCCGCCAGTCCCTCACCGAGATCAACGTCACGCCGCTCGTGGACG
TGATGCTGGTGCTGCTCATC

Product: protein TolQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLENPFPDLHMTELALSQLLPSAGVPLAAAGGLNYLEIATNSGPVGIGVLALLLGASAVSWAIIVKKWLQIRRAQDQSVK
FLETFWQSKRLDAIYQAAESLGASPLSHVFRAGYVELSKVTARKNEGDPGAMSDQLGGIENVERALKRAAASEVTALERQ
VPFLGTTASAAPFVGLFGTVWGIMRAFHEIYLMGNANLATVAKPISEALIATAVGLFAAIPAVVAYNFFLSKIRVLDSEM
TNFSNDFLNIVRRHFFS

Sequences:

>Translated_257_residues
MLENPFPDLHMTELALSQLLPSAGVPLAAAGGLNYLEIATNSGPVGIGVLALLLGASAVSWAIIVKKWLQIRRAQDQSVK
FLETFWQSKRLDAIYQAAESLGASPLSHVFRAGYVELSKVTARKNEGDPGAMSDQLGGIENVERALKRAAASEVTALERQ
VPFLGTTASAAPFVGLFGTVWGIMRAFHEIYLMGNANLATVAKPISEALIATAVGLFAAIPAVVAYNFFLSKIRVLDSEM
TNFSNDFLNIVRRHFFS
>Mature_257_residues
MLENPFPDLHMTELALSQLLPSAGVPLAAAGGLNYLEIATNSGPVGIGVLALLLGASAVSWAIIVKKWLQIRRAQDQSVK
FLETFWQSKRLDAIYQAAESLGASPLSHVFRAGYVELSKVTARKNEGDPGAMSDQLGGIENVERALKRAAASEVTALERQ
VPFLGTTASAAPFVGLFGTVWGIMRAFHEIYLMGNANLATVAKPISEALIATAVGLFAAIPAVVAYNFFLSKIRVLDSEM
TNFSNDFLNIVRRHFFS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=213, Percent_Identity=37.5586854460094, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789381, Length=187, Percent_Identity=39.0374331550802, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 27667; Mature: 27667

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENPFPDLHMTELALSQLLPSAGVPLAAAGGLNYLEIATNSGPVGIGVLALLLGASAVS
CCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
WAIIVKKWLQIRRAQDQSVKFLETFWQSKRLDAIYQAAESLGASPLSHVFRAGYVELSKV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHH
TARKNEGDPGAMSDQLGGIENVERALKRAAASEVTALERQVPFLGTTASAAPFVGLFGTV
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
WGIMRAFHEIYLMGNANLATVAKPISEALIATAVGLFAAIPAVVAYNFFLSKIRVLDSEM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNFSNDFLNIVRRHFFS
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLENPFPDLHMTELALSQLLPSAGVPLAAAGGLNYLEIATNSGPVGIGVLALLLGASAVS
CCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
WAIIVKKWLQIRRAQDQSVKFLETFWQSKRLDAIYQAAESLGASPLSHVFRAGYVELSKV
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHH
TARKNEGDPGAMSDQLGGIENVERALKRAAASEVTALERQVPFLGTTASAAPFVGLFGTV
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
WGIMRAFHEIYLMGNANLATVAKPISEALIATAVGLFAAIPAVVAYNFFLSKIRVLDSEM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNFSNDFLNIVRRHFFS
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]