Click here to switch to the map view.

The map label for this gene is hscB [H]

Identifier: 220915740

GI number: 220915740

Start: 698224

End: 698841

Strand: Direct

Name: hscB [H]

Synonym: A2cp1_0621

Alternate gene names: 220915740

Gene position: 698224-698841 (Clockwise)

Preceding gene: 220915739

Following gene: 220915741

Centisome position: 13.88

GC content: 71.52

Gene sequence:

>618_bases
GTGGCGCACTGCTGGAGCTGCAAGGCGCAGGAGGAGCAGCAGACCCCCTTCTGCCCGAGCTGCCAGAAGATCCAGCCGGT
CGGGCGCACCGAGGACTACTTCTCGCTGCTCGGCCTGCCGCGCCAGTTCGCGCTCGATCCCGCGGAGCTCGACCGCAACT
TCCGCACGCTCTCCCGCTCGCTGCACCCCGATCGCTTCGCCAAGGCGGAGGCGCGAGAGCGCCGCCTCTCGCTGGAGCGC
GCCACCCGGCTGAACGACGCGCACCGCTACCTGAAGGACTGGCGCCTCCGCGCCGCCTACCTGCTCAAGCTGGCCGGCAC
CGACGTGTTCGCCGAGGGCAGGACCTTCGCCGATCCGCAGTTCCTGGAGGAGCAGCTGGAGTGGCGCGAGGACATGGCGC
TCGCCCAGTCGGATCGCGACGCGGCCGGCCTGCGCGACATCGCGGCCCGCGCCCGGGCCCGCCTGCAGGCCCTCGAGACC
GAGGTGGCGCGCTGCTTCGAGGACGATCACTGGTTCTCGGAGCTCGTGATCGAGATCGCTCGCCTGCTCTCCCGCGCCCG
GTATTACGATCACATCATCGCGGACGCGGAGCGCGCCAGCGCGGCGGTCGCGTCCTAG

Upstream 100 bases:

>100_bases
CACGATCTAGCCGCCCCGGCTGGATCGCGTTCCCGCTTCGCCCCGCGCCACGGCGCGCAGGCAGGGCGGGAACGATCGTT
ATCGGGGCCACGGAGGCCGC

Downstream 100 bases:

>100_bases
CGATCCGTAGTAGAAGAAAGCCATGCCCCGCGCGATCGGGATCGACCTCGGCACGACCAACTCGCTCGTCGCCCACGTGG
ACGAGCGGAACCGCCCCCGC

Product: co-chaperone Hsc20

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAHCWSCKAQEEQQTPFCPSCQKIQPVGRTEDYFSLLGLPRQFALDPAELDRNFRTLSRSLHPDRFAKAEARERRLSLER
ATRLNDAHRYLKDWRLRAAYLLKLAGTDVFAEGRTFADPQFLEEQLEWREDMALAQSDRDAAGLRDIAARARARLQALET
EVARCFEDDHWFSELVIEIARLLSRARYYDHIIADAERASAAVAS

Sequences:

>Translated_205_residues
MAHCWSCKAQEEQQTPFCPSCQKIQPVGRTEDYFSLLGLPRQFALDPAELDRNFRTLSRSLHPDRFAKAEARERRLSLER
ATRLNDAHRYLKDWRLRAAYLLKLAGTDVFAEGRTFADPQFLEEQLEWREDMALAQSDRDAAGLRDIAARARARLQALET
EVARCFEDDHWFSELVIEIARLLSRARYYDHIIADAERASAAVAS
>Mature_204_residues
AHCWSCKAQEEQQTPFCPSCQKIQPVGRTEDYFSLLGLPRQFALDPAELDRNFRTLSRSLHPDRFAKAEARERRLSLERA
TRLNDAHRYLKDWRLRAAYLLKLAGTDVFAEGRTFADPQFLEEQLEWREDMALAQSDRDAAGLRDIAARARARLQALETE
VARCFEDDHWFSELVIEIARLLSRARYYDHIIADAERASAAVAS

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=192, Percent_Identity=31.7708333333333, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788876, Length=140, Percent_Identity=32.8571428571429, Blast_Score=80, Evalue=7e-17,
Organism=Drosophila melanogaster, GI161084223, Length=184, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 23687; Mature: 23556

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHCWSCKAQEEQQTPFCPSCQKIQPVGRTEDYFSLLGLPRQFALDPAELDRNFRTLSRS
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
LHPDRFAKAEARERRLSLERATRLNDAHRYLKDWRLRAAYLLKLAGTDVFAEGRTFADPQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHH
FLEEQLEWREDMALAQSDRDAAGLRDIAARARARLQALETEVARCFEDDHWFSELVIEIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RLLSRARYYDHIIADAERASAAVAS
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AHCWSCKAQEEQQTPFCPSCQKIQPVGRTEDYFSLLGLPRQFALDPAELDRNFRTLSRS
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCHHHCCCHHHHHHHHHHHHHH
LHPDRFAKAEARERRLSLERATRLNDAHRYLKDWRLRAAYLLKLAGTDVFAEGRTFADPQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHH
FLEEQLEWREDMALAQSDRDAAGLRDIAARARARLQALETEVARCFEDDHWFSELVIEIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RLLSRARYYDHIIADAERASAAVAS
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]