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The map label for this gene is dsbD [H]

Identifier: 220915736

GI number: 220915736

Start: 694484

End: 695899

Strand: Reverse

Name: dsbD [H]

Synonym: A2cp1_0617

Alternate gene names: 220915736

Gene position: 695899-694484 (Counterclockwise)

Preceding gene: 220915744

Following gene: 220915734

Centisome position: 13.84

GC content: 74.08

Gene sequence:

>1416_bases
ATGCGCTTCGCCATCCGCACCCTCCTCGCTGCCCTCACCTTCGCCGCCGTGGCGTGGATCCCAGACCTGATCGGTCTCGG
ACCCGCTGGGGGGTCGAGCGATCTGCGCCTCGGCGCACTGCTGGCGGAGGGGTCCGTGCTGGCGTTCGCGGTCGCGTTCG
CCGGCGGCGTGGCGACCAGCCTCACGCCGTGCGTGTACCCGCTCATCCCGATCACCGTCTCGATCTTCGGCGCCCGCAAG
GCGGGCTCCCGCGGCGAGGCGATGGCGGTGTCGGCGCTCTACGTCCTCGGCATCGCCGCGATGTACTCCGCCCTCGGGGT
GGGTGCGGCGCTCACCGGCAAGGCGTTCGGCAGCGTGATGCAGAACCCGTGGGTGATCGGGTTCGTGGCGCTCGTGCTCG
CCGCCATGGCGGCCTCGATGTTCGGCGCGTTCGAGCTGCAGCTCCCGGCCTCGATGCAGGCCCGCCTGAACGGCGTGGGC
GGCGCGGGCCGCGCCGGCGCCTTCGCGATGGGGCTCGTCTCCGGGATCATCGCCGCGCCCTGCACCGGGCCGGTGCTCGC
CGCCGCGCTCACCTTCGTGGCGGCCAAGGGCTCGGTCGCGTTCGGCTTCGGCATCATGTTCGCGTACGCGCTCGGCATGG
GGCTGCTGTTCTTCCTCATCGGCGCGTTCTCCATCTCGCTCCCGAAGAGCGGGGCGTGGATGGAGACGGTGAAGTCGGTG
TTCGGCGTGGCGCTGCTCGCGGCCGCGCTCATCTTCCTGAAGGACGCGTTCCCCGCGCTGAAGCCGCTGTTCTCGGCGGC
CCGCGGCGCGGCGTTCGCGGCGGCCGCCGCGGCGGCGCTCGGCGTGCTGGCCGGCGCGCTCTCCGGGAGCTTCCACGCGC
CCGCGCGGCAGCGGCTCGCGAAGGGGCTCGGCGTCGCGCTCCTGGTGGGCGGGATCGCCTACGCGGCCGGCGCGGCCGGC
GCCCGCGAGCGGGCGCGCGCGCACGCGGGCTTCTCGTGGCTCCACTCCGAGGCGGAGGCGCTCGCGCTCGCCAAGGCCGA
GGGCCGGCCGGTCATCATCGACTTCTGGGCCGACTGGTGCACCGCCTGCAAGGAGCTGGACAAGATCGCCTGGGCGAAGC
CGGAGGTGCAGGACGAGGCCGCCCGGTTCGTGGCGCTGAAGCTCGACGGCACCGACGGCTCGGACGCGTTCAACGCGCTC
GCCGAGAAGTACGGCGTGGTGGGCATGCCCACCGTGATCTTCATCGACCCGCGCGGTCGCGAGGTGCCGGACCGCGTGAT
GGGCGCCATCTCCGCCGGCGAGATGGTGCAGAAGCTCCGCGCCGTGGACCGCGCCTGCGAGGGCCAGCCGTCGCCGGCGA
AGCCCGCCGCGGTGCAGGGCGAGCCGGTCGCGATGGCCTGCGCCTCGCGCTGGTAG

Upstream 100 bases:

>100_bases
GTCGAGTATAAAGATTCACGTCATCGGGTCAAGCGGCCCCCCTCTACCAAACTATCGGGCGCGACAGGACTTTTTTTCTT
AGATCTGCAAGGCCATTCGC

Downstream 100 bases:

>100_bases
CAGCCCGGCGCGAGGGCGCAGCCCTCGTCACGATCAGAACGCCCGGAAGCCTCCGACGATCAGGAACGTCAGCTCGCCCC
GCGTCTCCTTCAGCGGCGCG

Product: cytochrome c biogenesis protein transmembrane protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRFAIRTLLAALTFAAVAWIPDLIGLGPAGGSSDLRLGALLAEGSVLAFAVAFAGGVATSLTPCVYPLIPITVSIFGARK
AGSRGEAMAVSALYVLGIAAMYSALGVGAALTGKAFGSVMQNPWVIGFVALVLAAMAASMFGAFELQLPASMQARLNGVG
GAGRAGAFAMGLVSGIIAAPCTGPVLAAALTFVAAKGSVAFGFGIMFAYALGMGLLFFLIGAFSISLPKSGAWMETVKSV
FGVALLAAALIFLKDAFPALKPLFSAARGAAFAAAAAAALGVLAGALSGSFHAPARQRLAKGLGVALLVGGIAYAAGAAG
ARERARAHAGFSWLHSEAEALALAKAEGRPVIIDFWADWCTACKELDKIAWAKPEVQDEAARFVALKLDGTDGSDAFNAL
AEKYGVVGMPTVIFIDPRGREVPDRVMGAISAGEMVQKLRAVDRACEGQPSPAKPAAVQGEPVAMACASRW

Sequences:

>Translated_471_residues
MRFAIRTLLAALTFAAVAWIPDLIGLGPAGGSSDLRLGALLAEGSVLAFAVAFAGGVATSLTPCVYPLIPITVSIFGARK
AGSRGEAMAVSALYVLGIAAMYSALGVGAALTGKAFGSVMQNPWVIGFVALVLAAMAASMFGAFELQLPASMQARLNGVG
GAGRAGAFAMGLVSGIIAAPCTGPVLAAALTFVAAKGSVAFGFGIMFAYALGMGLLFFLIGAFSISLPKSGAWMETVKSV
FGVALLAAALIFLKDAFPALKPLFSAARGAAFAAAAAAALGVLAGALSGSFHAPARQRLAKGLGVALLVGGIAYAAGAAG
ARERARAHAGFSWLHSEAEALALAKAEGRPVIIDFWADWCTACKELDKIAWAKPEVQDEAARFVALKLDGTDGSDAFNAL
AEKYGVVGMPTVIFIDPRGREVPDRVMGAISAGEMVQKLRAVDRACEGQPSPAKPAAVQGEPVAMACASRW
>Mature_471_residues
MRFAIRTLLAALTFAAVAWIPDLIGLGPAGGSSDLRLGALLAEGSVLAFAVAFAGGVATSLTPCVYPLIPITVSIFGARK
AGSRGEAMAVSALYVLGIAAMYSALGVGAALTGKAFGSVMQNPWVIGFVALVLAAMAASMFGAFELQLPASMQARLNGVG
GAGRAGAFAMGLVSGIIAAPCTGPVLAAALTFVAAKGSVAFGFGIMFAYALGMGLLFFLIGAFSISLPKSGAWMETVKSV
FGVALLAAALIFLKDAFPALKPLFSAARGAAFAAAAAAALGVLAGALSGSFHAPARQRLAKGLGVALLVGGIAYAAGAAG
ARERARAHAGFSWLHSEAEALALAKAEGRPVIIDFWADWCTACKELDKIAWAKPEVQDEAARFVALKLDGTDGSDAFNAL
AEKYGVVGMPTVIFIDPRGREVPDRVMGAISAGEMVQKLRAVDRACEGQPSPAKPAAVQGEPVAMACASRW

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=404, Percent_Identity=34.6534653465347, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 47755; Mature: 47755

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFAIRTLLAALTFAAVAWIPDLIGLGPAGGSSDLRLGALLAEGSVLAFAVAFAGGVATS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCHHHH
LTPCVYPLIPITVSIFGARKAGSRGEAMAVSALYVLGIAAMYSALGVGAALTGKAFGSVM
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QNPWVIGFVALVLAAMAASMFGAFELQLPASMQARLNGVGGAGRAGAFAMGLVSGIIAAP
CCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
CTGPVLAAALTFVAAKGSVAFGFGIMFAYALGMGLLFFLIGAFSISLPKSGAWMETVKSV
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FGVALLAAALIFLKDAFPALKPLFSAARGAAFAAAAAAALGVLAGALSGSFHAPARQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KGLGVALLVGGIAYAAGAAGARERARAHAGFSWLHSEAEALALAKAEGRPVIIDFWADWC
HHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
TACKELDKIAWAKPEVQDEAARFVALKLDGTDGSDAFNALAEKYGVVGMPTVIFIDPRGR
HHHHHHHHHHCCCCCHHHHHCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
EVPDRVMGAISAGEMVQKLRAVDRACEGQPSPAKPAAVQGEPVAMACASRW
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MRFAIRTLLAALTFAAVAWIPDLIGLGPAGGSSDLRLGALLAEGSVLAFAVAFAGGVATS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCHHHH
LTPCVYPLIPITVSIFGARKAGSRGEAMAVSALYVLGIAAMYSALGVGAALTGKAFGSVM
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QNPWVIGFVALVLAAMAASMFGAFELQLPASMQARLNGVGGAGRAGAFAMGLVSGIIAAP
CCCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
CTGPVLAAALTFVAAKGSVAFGFGIMFAYALGMGLLFFLIGAFSISLPKSGAWMETVKSV
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FGVALLAAALIFLKDAFPALKPLFSAARGAAFAAAAAAALGVLAGALSGSFHAPARQRLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KGLGVALLVGGIAYAAGAAGARERARAHAGFSWLHSEAEALALAKAEGRPVIIDFWADWC
HHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
TACKELDKIAWAKPEVQDEAARFVALKLDGTDGSDAFNALAEKYGVVGMPTVIFIDPRGR
HHHHHHHHHHCCCCCHHHHHCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
EVPDRVMGAISAGEMVQKLRAVDRACEGQPSPAKPAAVQGEPVAMACASRW
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA