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The map label for this gene is pafC [H]

Identifier: 220915727

GI number: 220915727

Start: 684091

End: 685185

Strand: Direct

Name: pafC [H]

Synonym: A2cp1_0608

Alternate gene names: 220915727

Gene position: 684091-685185 (Clockwise)

Preceding gene: 220915726

Following gene: 220915728

Centisome position: 13.6

GC content: 79.09

Gene sequence:

>1095_bases
GTGAGCGCCGCCGGGTCGCGGCGCCGTCCCGCCGGGGCGCGGGCGAAGGCGCCCACGAAGGCGGCGGCCGCCAAGGCGCC
GCCGGCGGCGAAGCCGGCCCGCGGTGCCGCGCGCGCCGCCCCCCGTCCCTCCGCCCGCGCGCCCGCCGCGCCGAAGAAGG
CCGACCCGCGCGACCGGCTCCGCCGCGTGCTGTTCCTCGTGCCCTACGCGGTCCGCCACCCGGGCATCCCGGTGCGCGAC
CTGGCGCGGCGCTGCGGCTGCACCGAGAAGGAGCTGCTCGAGGACCTCGACTTCCTGCTCGAGGTCGGCTCGCCCCCGTT
CGCCCCCGACGACTTCCTCGACCTCTACGTCGAGGGCGACCGCGTCTACGTGGCGCTGCACCAGAGCTTCTCGCGCCCGC
CGCGGTTCACCGAGAGCGAAGCCGCCGCGCTCGCCGCGGCCGCGGCCGCGCTGGGCGGCGAGGGGCGCGAGCGCGCCGTG
AAGGCGCTCCGCGACTCGGTCCCCCGCGACCGGCGCGCCAGCTTCGACGAGCTGGTGGAGCGCATCTACGCCGGCGCCCC
CCCGGCGCGGGACTCGGTGCTGGGCCGGCTCCAGCGCGCCATCGCCGAGCGGCGCGCGGTGCGCCTCGCCTACCACTCCG
CCTCGCGCGACGCCGAGACCGACCGGACCGTGCGCCCGTACACGCTCGCGCAGCGCTTCGGCCACTGGTACCTGTACGGG
CACGACGCCGAGCGGGGGAAGGCGCTCGCCTTCCGCCTCGACCGGATCCGGGAGTGCACCTTGCTGCCGGAGCGCTTCGA
GCCGCCCACCGAGGCCGAGCTGGCCAGGGCCCGCCTGTTCTCCGAGGCGGCCGGCGAGCCCGTGCGGATCCGGCTCGGCG
CGCAGGCGGCGCCCTGGGCGGTGTCGCGTCCCGGCATCTCGCTGGTGGAGCGGACGCCGGGCGGCGGGGCCGTGGTGGAG
GTGGCCGGCGCCGGGAACGACTGGGCCACCCGGTTCGCGCTCTCGCTGGGTGGCGGCGCCGAGGTGGTCGCGCCGGCCGC
CGCGCGCCGCGCGTTCGCCGAGACGGTGCGTCGCACGCTGGCGCGCTACCGCTGA

Upstream 100 bases:

>100_bases
GCCACGTGCTCGCGCTGGGCGACGGGGCCGAGCTCCTCGCGCCGAAGGCGCTGCGCGACCGCGCGCGGGCGGTGCTCGAG
CAGCTCGCGGAGGAGCTGGC

Downstream 100 bases:

>100_bases
CGCGCCGGGTGCGTCCGGCACGCACCGTGCGGGGTGGGGCCGCTGTCCCGGGAACGAATGACCCAGGGTCGCGCGACGGC
CCTGGGATCCCTCCGGAAAA

Product: transcriptional regulator-like protein

Products: NA

Alternate protein names: Proteasome accessory factor C [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSAAGSRRRPAGARAKAPTKAAAAKAPPAAKPARGAARAAPRPSARAPAAPKKADPRDRLRRVLFLVPYAVRHPGIPVRD
LARRCGCTEKELLEDLDFLLEVGSPPFAPDDFLDLYVEGDRVYVALHQSFSRPPRFTESEAAALAAAAAALGGEGRERAV
KALRDSVPRDRRASFDELVERIYAGAPPARDSVLGRLQRAIAERRAVRLAYHSASRDAETDRTVRPYTLAQRFGHWYLYG
HDAERGKALAFRLDRIRECTLLPERFEPPTEAELARARLFSEAAGEPVRIRLGAQAAPWAVSRPGISLVERTPGGGAVVE
VAGAGNDWATRFALSLGGGAEVVAPAAARRAFAETVRRTLARYR

Sequences:

>Translated_364_residues
MSAAGSRRRPAGARAKAPTKAAAAKAPPAAKPARGAARAAPRPSARAPAAPKKADPRDRLRRVLFLVPYAVRHPGIPVRD
LARRCGCTEKELLEDLDFLLEVGSPPFAPDDFLDLYVEGDRVYVALHQSFSRPPRFTESEAAALAAAAAALGGEGRERAV
KALRDSVPRDRRASFDELVERIYAGAPPARDSVLGRLQRAIAERRAVRLAYHSASRDAETDRTVRPYTLAQRFGHWYLYG
HDAERGKALAFRLDRIRECTLLPERFEPPTEAELARARLFSEAAGEPVRIRLGAQAAPWAVSRPGISLVERTPGGGAVVE
VAGAGNDWATRFALSLGGGAEVVAPAAARRAFAETVRRTLARYR
>Mature_363_residues
SAAGSRRRPAGARAKAPTKAAAAKAPPAAKPARGAARAAPRPSARAPAAPKKADPRDRLRRVLFLVPYAVRHPGIPVRDL
ARRCGCTEKELLEDLDFLLEVGSPPFAPDDFLDLYVEGDRVYVALHQSFSRPPRFTESEAAALAAAAAALGGEGRERAVK
ALRDSVPRDRRASFDELVERIYAGAPPARDSVLGRLQRAIAERRAVRLAYHSASRDAETDRTVRPYTLAQRFGHWYLYGH
DAERGKALAFRLDRIRECTLLPERFEPPTEAELARARLFSEAAGEPVRIRLGAQAAPWAVSRPGISLVERTPGGGAVVEV
AGAGNDWATRFALSLGGGAEVVAPAAARRAFAETVRRTLARYR

Specific function: Part of the pafABC operon, but pafC does not seem to be involved in pupylation or substrate degradation. Appears to play at least a small role in resistance to reactive nitrogen intermediates (RNI) in vitro [H]

COG id: COG2378

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pafC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39442; Mature: 39311

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAGSRRRPAGARAKAPTKAAAAKAPPAAKPARGAARAAPRPSARAPAAPKKADPRDRL
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RRVLFLVPYAVRHPGIPVRDLARRCGCTEKELLEDLDFLLEVGSPPFAPDDFLDLYVEGD
HHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
RVYVALHQSFSRPPRFTESEAAALAAAAAALGGEGRERAVKALRDSVPRDRRASFDELVE
EEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
RIYAGAPPARDSVLGRLQRAIAERRAVRLAYHSASRDAETDRTVRPYTLAQRFGHWYLYG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEE
HDAERGKALAFRLDRIRECTLLPERFEPPTEAELARARLFSEAAGEPVRIRLGAQAAPWA
CCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
VSRPGISLVERTPGGGAVVEVAGAGNDWATRFALSLGGGAEVVAPAAARRAFAETVRRTL
CCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
ARYR
HHCC
>Mature Secondary Structure 
SAAGSRRRPAGARAKAPTKAAAAKAPPAAKPARGAARAAPRPSARAPAAPKKADPRDRL
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
RRVLFLVPYAVRHPGIPVRDLARRCGCTEKELLEDLDFLLEVGSPPFAPDDFLDLYVEGD
HHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
RVYVALHQSFSRPPRFTESEAAALAAAAAALGGEGRERAVKALRDSVPRDRRASFDELVE
EEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
RIYAGAPPARDSVLGRLQRAIAERRAVRLAYHSASRDAETDRTVRPYTLAQRFGHWYLYG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEE
HDAERGKALAFRLDRIRECTLLPERFEPPTEAELARARLFSEAAGEPVRIRLGAQAAPWA
CCCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
VSRPGISLVERTPGGGAVVEVAGAGNDWATRFALSLGGGAEVVAPAAARRAFAETVRRTL
CCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHH
ARYR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]