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The map label for this gene is mtaD [H]

Identifier: 220915715

GI number: 220915715

Start: 670706

End: 672103

Strand: Reverse

Name: mtaD [H]

Synonym: A2cp1_0596

Alternate gene names: 220915715

Gene position: 672103-670706 (Counterclockwise)

Preceding gene: 220915720

Following gene: 220915714

Centisome position: 13.36

GC content: 79.54

Gene sequence:

>1398_bases
GTGACCACCGCGCAGGCGTTCCAGCCCGAGCTCCTCCTCGCCGGCGGCTCCCTCCACGAGGGGGCCGCGCTCTCGGTCAA
GGACGGCGTCGTCGCCGCCATCGGGCCGCCGCTGCCCGGGTTCCAGCGCGTCCCGCTCCCCGGGCGCATCCTGGTCCCCG
GCTTCGTGTCCGCCCACGGCCACTCCTTCCAGCGCGCGCTGCGCGGCCGCACCGAGGCGCGCGCGGGCGCCGGCGGGCGG
AGCGACTTCTGGGGGTGGCGCTCGGCCATGTACGCCGCCGCGCGCCGGCTCGACCCCGACCTGCTCGAGGCGGTGGCCCG
CCTCGCGTTCTTCGAGCTGGCCCGGGCCGGCGTCACCTGCGCCGGCGAGTTCCACTACCTGCACCTCGACCCCGACGGCC
GGCCCTACGCCGATCCCGCCGAGCTCGAGCTGCGCGTGGTCCGCGCCGCCCGCGCGGTGGGCCTGCGCATCGTGCTGCTC
CGCGCCGCGTACGCGCGCGCCGGCGCCGGGACCGAGCCGGATCCGGCGCAGCGCCGCTTCGTGGAGCCGTCGCCGGAGGT
GTTCCTGGAGCGGCTCGAGCACCTCGCCCGCCAGCTCCGCAACGACGACGGCGTCCGGGTCGGCATCGCGCCGCACAGCG
TCCGGGCCTGCCCGCCGGCCTGGCTCTCGGCGCTCGCCGGCGCGGCCCGGGCGCGCGACCTGCCGCTGCACGTGCACGCC
GCCGAGCAGCCGGCCGAGGTCGCGGCCTGCCGGGCCGAGCACGGCAGGAGCCCGGTGCAGCTCCTCGCCGACGCCGGCGC
GCTCGAGGCCCGCACCACGCTCGTGCACGCGATCCACCTCGACGACGCCGACGTCGCGGCCATCGGCCGCGCCGGCGCCA
CCGTCTGCGCCTGCCCGCTGACCGAGCGCAACCTGGGCGACGGGGTGGTCCCGGCCGACCGGCTGGTGGCGGCGGGGGCG
CGCCTGGCGCTCGGGGTGGACGCGCACGCCGAGGCCGACCCGCTCGGCGAGGCCCGGGCGCTCGAGCTGCAGCTCCGGCT
GGTGCGCGGCGAGCGGGCGGTGCTGGACGGGCCGCCGGGCACGCTCGCGGCGCGGCTCTTCGACGCGGCCACGGCCGGCG
GGATGGCGTCGCTCGGGCTCGAGGGCGGGCGGCTCGCGGTGGGCGAGCCGGCCGACTTCGTGCTCGTGGACGTGGACGAC
CCTTCCATCGCCGGGGGCGAGCGGGACGCGCTGCTGCCCTCGCTCGTGTTCGGCGCGCAGCCCGGGGCGGTGCGGAGCAC
GTTCGTGGCAGGGGAGCCGGTGGTCGAGGACGGGTGGGCGCCGCCGGGGCGACCCACCGGCGCGGAGCTGCTGAAGGACT
TCCGCGCCGCCATGCGCGCCCTGTGGGGCGGCGCGTGA

Upstream 100 bases:

>100_bases
GGCGATACCGGCAGCGGGGCCGCCCGGGCAACGACGGCCGCCCGGCCGGCGCCCGCGCGCGGGCTGGCGGCGCGGCCGTC
CGCGGGGTAACCCTGGGACC

Downstream 100 bases:

>100_bases
TAGAGAAGCAGCGCGGCGGCGCGGCCTCGCGTAGGCTCGGGAGCGCATGGATCTCGTCCCGCTGCTCCGGTCCCTGGTCG
CGCTCGACACGACCTCCGCC

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTTAQAFQPELLLAGGSLHEGAALSVKDGVVAAIGPPLPGFQRVPLPGRILVPGFVSAHGHSFQRALRGRTEARAGAGGR
SDFWGWRSAMYAAARRLDPDLLEAVARLAFFELARAGVTCAGEFHYLHLDPDGRPYADPAELELRVVRAARAVGLRIVLL
RAAYARAGAGTEPDPAQRRFVEPSPEVFLERLEHLARQLRNDDGVRVGIAPHSVRACPPAWLSALAGAARARDLPLHVHA
AEQPAEVAACRAEHGRSPVQLLADAGALEARTTLVHAIHLDDADVAAIGRAGATVCACPLTERNLGDGVVPADRLVAAGA
RLALGVDAHAEADPLGEARALELQLRLVRGERAVLDGPPGTLAARLFDAATAGGMASLGLEGGRLAVGEPADFVLVDVDD
PSIAGGERDALLPSLVFGAQPGAVRSTFVAGEPVVEDGWAPPGRPTGAELLKDFRAAMRALWGGA

Sequences:

>Translated_465_residues
MTTAQAFQPELLLAGGSLHEGAALSVKDGVVAAIGPPLPGFQRVPLPGRILVPGFVSAHGHSFQRALRGRTEARAGAGGR
SDFWGWRSAMYAAARRLDPDLLEAVARLAFFELARAGVTCAGEFHYLHLDPDGRPYADPAELELRVVRAARAVGLRIVLL
RAAYARAGAGTEPDPAQRRFVEPSPEVFLERLEHLARQLRNDDGVRVGIAPHSVRACPPAWLSALAGAARARDLPLHVHA
AEQPAEVAACRAEHGRSPVQLLADAGALEARTTLVHAIHLDDADVAAIGRAGATVCACPLTERNLGDGVVPADRLVAAGA
RLALGVDAHAEADPLGEARALELQLRLVRGERAVLDGPPGTLAARLFDAATAGGMASLGLEGGRLAVGEPADFVLVDVDD
PSIAGGERDALLPSLVFGAQPGAVRSTFVAGEPVVEDGWAPPGRPTGAELLKDFRAAMRALWGGA
>Mature_464_residues
TTAQAFQPELLLAGGSLHEGAALSVKDGVVAAIGPPLPGFQRVPLPGRILVPGFVSAHGHSFQRALRGRTEARAGAGGRS
DFWGWRSAMYAAARRLDPDLLEAVARLAFFELARAGVTCAGEFHYLHLDPDGRPYADPAELELRVVRAARAVGLRIVLLR
AAYARAGAGTEPDPAQRRFVEPSPEVFLERLEHLARQLRNDDGVRVGIAPHSVRACPPAWLSALAGAARARDLPLHVHAA
EQPAEVAACRAEHGRSPVQLLADAGALEARTTLVHAIHLDDADVAAIGRAGATVCACPLTERNLGDGVVPADRLVAAGAR
LALGVDAHAEADPLGEARALELQLRLVRGERAVLDGPPGTLAARLFDAATAGGMASLGLEGGRLAVGEPADFVLVDVDDP
SIAGGERDALLPSLVFGAQPGAVRSTFVAGEPVVEDGWAPPGRPTGAELLKDFRAAMRALWGGA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=438, Percent_Identity=23.7442922374429, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540282, Length=422, Percent_Identity=30.8056872037915, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24643849, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48502; Mature: 48371

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAQAFQPELLLAGGSLHEGAALSVKDGVVAAIGPPLPGFQRVPLPGRILVPGFVSAHG
CCCCCCCCCCEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEEECCCHHHHCC
HSFQRALRGRTEARAGAGGRSDFWGWRSAMYAAARRLDPDLLEAVARLAFFELARAGVTC
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
AGEFHYLHLDPDGRPYADPAELELRVVRAARAVGLRIVLLRAAYARAGAGTEPDPAQRRF
ECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
VEPSPEVFLERLEHLARQLRNDDGVRVGIAPHSVRACPPAWLSALAGAARARDLPLHVHA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
AEQPAEVAACRAEHGRSPVQLLADAGALEARTTLVHAIHLDDADVAAIGRAGATVCACPL
CCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHEEEEEEEECCCCCHHHHCCCCCEEEECCC
TERNLGDGVVPADRLVAAGARLALGVDAHAEADPLGEARALELQLRLVRGERAVLDGPPG
CCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCCH
TLAARLFDAATAGGMASLGLEGGRLAVGEPADFVLVDVDDPSIAGGERDALLPSLVFGAQ
HHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCC
PGAVRSTFVAGEPVVEDGWAPPGRPTGAELLKDFRAAMRALWGGA
CCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTAQAFQPELLLAGGSLHEGAALSVKDGVVAAIGPPLPGFQRVPLPGRILVPGFVSAHG
CCCCCCCCCEEEECCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCEEECCCHHHHCC
HSFQRALRGRTEARAGAGGRSDFWGWRSAMYAAARRLDPDLLEAVARLAFFELARAGVTC
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
AGEFHYLHLDPDGRPYADPAELELRVVRAARAVGLRIVLLRAAYARAGAGTEPDPAQRRF
ECEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCC
VEPSPEVFLERLEHLARQLRNDDGVRVGIAPHSVRACPPAWLSALAGAARARDLPLHVHA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEC
AEQPAEVAACRAEHGRSPVQLLADAGALEARTTLVHAIHLDDADVAAIGRAGATVCACPL
CCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHEEEEEEEECCCCCHHHHCCCCCEEEECCC
TERNLGDGVVPADRLVAAGARLALGVDAHAEADPLGEARALELQLRLVRGERAVLDGPPG
CCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCCH
TLAARLFDAATAGGMASLGLEGGRLAVGEPADFVLVDVDDPSIAGGERDALLPSLVFGAQ
HHHHHHHHHHHCCCHHHCCCCCCEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCC
PGAVRSTFVAGEPVVEDGWAPPGRPTGAELLKDFRAAMRALWGGA
CCCHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA