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The map label for this gene is clpB [H]

Identifier: 220915533

GI number: 220915533

Start: 466526

End: 469138

Strand: Reverse

Name: clpB [H]

Synonym: A2cp1_0414

Alternate gene names: 220915533

Gene position: 469138-466526 (Counterclockwise)

Preceding gene: 220915552

Following gene: 220915532

Centisome position: 9.33

GC content: 71.76

Gene sequence:

>2613_bases
ATGCGAATGGAAAAGCTCACCGTGAAGGCGCAGGAGGTCCTCGCCGCCGCGCAGGGGGAGGCGCGCCGACGCGACCACCA
GGCCGTGGACGTCGAGCACCTCGTGCTCGCGCTGCTCGCGCAGGAGGAGGGCATCGCGCGCCCGGTGCTGGAGAAGATCG
GCGCGGACCCGCGCCTGGTCGCCTCGCGGGTGGAGGACGAGCTGCGCTCGCTGCCGAAGGTGTCGGGCGCGGAGCCCTAC
CCGGCGAACCGGCTGCTGAAGCTGTTCGACCGGGCCGAGGACGAGGCGCGCAAGCTGAAGGACGAGTACGTCTCGACCGA
GCACCTGCTGCTCGCCGCCGCCGAGGACAAGGGCGGCGCCGGCGAGGCGCTGCGCGCGTCCGGCGCGACGCCCGAGCGCG
TCCGCCAGGCGGTGCAGGAGGTGCGGGGCGGCGCGCGCGTCACCTCGCCCGAGGCCGAGAGCCAGTACCGCGCGCTCGAG
AAGTACGCGAAGGACCTCACCGACCTCGCCAGGAAGGGCAAGCTCGACCCGGTCATCGGCCGCGACGACGAGATCCGGCG
CGTGGTCCAGATCCTGTCGCGCCGCACCAAGAACAACCCGGTGCTGGTGGGCGACCCCGGCGTGGGCAAGACCGCCATCG
TGGAGGGGCTGGCGCGCCGCATCGTGGACGGCGACGTGCCGGAGGGGCTGAAGAACAAGCGGCTGCTCGCGCTCGATCTC
GGCGCCCTGCTCGCCGGCGCGAAGTTCCGCGGCGAGTTCGAGGAGCGGCTGAAGGCGGTGCTGAAGGAGGTGACCGGCTC
GGAGGGCCAGATCATCCTCTTCATCGACGAGATGCACACCATCGTGGGCGCCGGCGCCGCCGAGGGCGCCATGGACGCGG
GCAACATGCTGAAGCCCGCGCTCGCCCGCGGCGAGCTGCACGCGGTGGGCGCCACCACCGTGAACGAGTACCGCAAGCAC
ATCGAGAAGGACCCCGCCCTGGAGCGGCGCTTCCAGCCGGTGTTCGTGGGCGAGCCGTCGCTCACCGACACCATCTCGAT
CCTGCGCGGCCTGAAGGATCGCTACGAGCTGCACCACAAGGTCCGCATCCAGGACGCGGCGCTGGTGGAGGCGGCGCGCC
TGTCGAGCCGCTACATCACCGATCGCTTCCTGCCCGACAAGGCCATCGACCTCGTGGACGAGGCGGCCAGCCGGCTGCGC
ATCGAGATCGACTCGATGCCGACCGAGGTGGACGAGGTGCGCCGGCGCATCGGGCAGCTCGAGATCGAGCGGCAGGGCCT
GCGCAAGGAGCAGGACGAGGCCTCCCGCGCGCGGCTCGCCGCGGTGGAGAAGGAGCTCGCCGCCCGCAACGAGGAGTTCA
CCGCGCTGAAGGGGCGCTGGGACGCCGAGAAGGCGGTGATCCAGGAGCTGAGCCAGGCGCGCCAGGAGCTGGAGGCGCTC
AAGGTCGAGCAGGCCGCGGCCGAGCGGCAGGCCGACTTCCAGAAGGCCGCCGAGATCAAGTTCGGCCGGCTGCCGGAGCT
GACGCGGCGGGTGAAGGCCGCCGAGGAGAAGCTCGCCGAGGCCCAGACCCGCGGCGCCATGCTGAAGGAGGAGGTCACGC
CGGAGGAGATCGGCGAGGTGGTCTCGAAGTGGACCGGCATCCCGGTGTCGCGCCTGATGGAGGGCGAGGTCGAGAAGCTG
CTCGGGATGGAGCAGCGCCTGCACGAGCGGGTGGTCGGGCAGGAGGAGGCGGTGAGCGCCGTCTCCGCGGCGGTGCGCCG
GGCCCGCTCCGGGCTGCAGGACCCGAACCGTCCCATCGGCTCGTTCATCTTCCTCGGCCCCACCGGCGTGGGGAAGACCG
AGACCGCCCGCGCGCTCGCGCAGTTCCTGTTCGACGACGAGCGGGCCATGGTCCGGCTCGACATGTCCGAGTACATGGAG
AAGCACACCGTCTCGCGGCTCATCGGCGCGCCGCCGGGCTACGTCGGCTACGAGGAGGGCGGGCAGCTCACCGAGGCGGT
GCGGCGCCGGCCTTACGCGGTGGTGCTCTTCGACGAGATCGAGAAGGCGCACCACGACGTGTTCAACGTGCTGCTCCAGA
TCCTCGACGACGGCCGGCTCACCGACGGCCAGGGCCGCACGGTGGACTTCCGCAACACGGTCATCATCATGACCTCCAAC
ATCGGCTCGGCCGACATCCAGCGCCTCGCCGGCCGCCCCGGGGCGGACATGCAGCAGATCCGCGAGGCGGCGCTCGAGCA
CCTGCGCGGCGAGTTCCGCCCGGAGTTCCTGAACCGGGTGGACGAGATCGTGGTGTTCCGGCCGCTCGGCCGCGAGGACG
TGGGGCGGATCGTGGAGATCCAGCTCGGCCGGCTGCGCAAGCTCATCGAGGAGCGCCACGTCAGCCTCGAGCTCACCGAG
GCGGCGCGCGAGGCCATCGCCGACGCCGGGTACGATCCGGTCTACGGCGCGCGCCCGCTGAAGCGCGCCATCCAGCGGAT
GGTGCAGGACCCGCTCGCGACGCGCCTGCTCCAGGGCGAGTTCAAGGCCGGCGACCACGTGGTGGTGGACGAGGGCAAGG
ACGGCAACATCGCGTTCCGCAAGGGCGAGCGGCCGGAGGTCACCGTCCACTGA

Upstream 100 bases:

>100_bases
CGGACGACCCTCCGGCGAGGGAACCCTCTCTCCTCCCGGCCCGGGCGGCGCGGCGGAACGGCTCGCTTGCCAGGGGTCCG
CCCGGTCTTACGTTGGCGCC

Downstream 100 bases:

>100_bases
GGGTGACGGGCGGCCGGCGGCGCGTGTGCGCCCCGGCCCCACCTCGCCCGACGCCGGGCCTGTCGGCCCCGGATCGCGGC
GGACTACAACCGGACGGCCC

Product: ATP-dependent chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLVASRVEDELRSLPKVSGAEPY
PANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGAGEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALE
KYAKDLTDLARKGKLDPVIGRDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPALARGELHAVGATTVNEYRKH
IEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHKVRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLR
IEIDSMPTEVDEVRRRIGQLEIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEVVSKWTGIPVSRLMEGEVEKL
LGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYME
KHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEIQLGRLRKLIEERHVSLELTE
AAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGEFKAGDHVVVDEGKDGNIAFRKGERPEVTVH

Sequences:

>Translated_870_residues
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLVASRVEDELRSLPKVSGAEPY
PANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGAGEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALE
KYAKDLTDLARKGKLDPVIGRDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPALARGELHAVGATTVNEYRKH
IEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHKVRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLR
IEIDSMPTEVDEVRRRIGQLEIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEVVSKWTGIPVSRLMEGEVEKL
LGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYME
KHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEIQLGRLRKLIEERHVSLELTE
AAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGEFKAGDHVVVDEGKDGNIAFRKGERPEVTVH
>Mature_870_residues
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLVASRVEDELRSLPKVSGAEPY
PANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGAGEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALE
KYAKDLTDLARKGKLDPVIGRDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPALARGELHAVGATTVNEYRKH
IEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHKVRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLR
IEIDSMPTEVDEVRRRIGQLEIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEVVSKWTGIPVSRLMEGEVEKL
LGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYME
KHTVSRLIGAPPGYVGYEEGGQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEIQLGRLRKLIEERHVSLELTE
AAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGEFKAGDHVVVDEGKDGNIAFRKGERPEVTVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=306, Percent_Identity=39.5424836601307, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=56.7285382830626, Blast_Score=976, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=407, Percent_Identity=41.5233415233415, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=730, Percent_Identity=52.6027397260274, Blast_Score=763, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=867, Percent_Identity=42.3298731257209, Blast_Score=667, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96682; Mature: 96682

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLV
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
ASRVEDELRSLPKVSGAEPYPANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCC
GEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALEKYAKDLTDLARKGKLDPVIG
CCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEH
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPA
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHH
LARGELHAVGATTVNEYRKHIEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHK
HHCCCEEECCHHHHHHHHHHHCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
VRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLRIEIDSMPTEVDEVRRRIGQL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCH
EIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VSKWTGIPVSRLMEGEVEKLLGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
SFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYMEKHTVSRLIGAPPGYVGYEEG
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
CHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHH
QLGRLRKLIEERHVSLELTEAAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
FKAGDHVVVDEGKDGNIAFRKGERPEVTVH
CCCCCEEEEECCCCCCEEEECCCCCCEECC
>Mature Secondary Structure
MRMEKLTVKAQEVLAAAQGEARRRDHQAVDVEHLVLALLAQEEGIARPVLEKIGADPRLV
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
ASRVEDELRSLPKVSGAEPYPANRLLKLFDRAEDEARKLKDEYVSTEHLLLAAAEDKGGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCC
GEALRASGATPERVRQAVQEVRGGARVTSPEAESQYRALEKYAKDLTDLARKGKLDPVIG
CCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RDDEIRRVVQILSRRTKNNPVLVGDPGVGKTAIVEGLARRIVDGDVPEGLKNKRLLALDL
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEH
GALLAGAKFRGEFEERLKAVLKEVTGSEGQIILFIDEMHTIVGAGAAEGAMDAGNMLKPA
HHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCHHHHHH
LARGELHAVGATTVNEYRKHIEKDPALERRFQPVFVGEPSLTDTISILRGLKDRYELHHK
HHCCCEEECCHHHHHHHHHHHCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHH
VRIQDAALVEAARLSSRYITDRFLPDKAIDLVDEAASRLRIEIDSMPTEVDEVRRRIGQL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCH
EIERQGLRKEQDEASRARLAAVEKELAARNEEFTALKGRWDAEKAVIQELSQARQELEAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KVEQAAAERQADFQKAAEIKFGRLPELTRRVKAAEEKLAEAQTRGAMLKEEVTPEEIGEV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VSKWTGIPVSRLMEGEVEKLLGMEQRLHERVVGQEEAVSAVSAAVRRARSGLQDPNRPIG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
SFIFLGPTGVGKTETARALAQFLFDDERAMVRLDMSEYMEKHTVSRLIGAPPGYVGYEEG
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLTEAVRRRPYAVVLFDEIEKAHHDVFNVLLQILDDGRLTDGQGRTVDFRNTVIIMTSN
CHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECC
IGSADIQRLAGRPGADMQQIREAALEHLRGEFRPEFLNRVDEIVVFRPLGREDVGRIVEI
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHH
QLGRLRKLIEERHVSLELTEAAREAIADAGYDPVYGARPLKRAIQRMVQDPLATRLLQGE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
FKAGDHVVVDEGKDGNIAFRKGERPEVTVH
CCCCCEEEEECCCCCCEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA