Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 220915348

GI number: 220915348

Start: 242400

End: 244223

Strand: Reverse

Name: hflX [H]

Synonym: A2cp1_0227

Alternate gene names: 220915348

Gene position: 244223-242400 (Counterclockwise)

Preceding gene: 220915349

Following gene: 220915347

Centisome position: 4.86

GC content: 75.44

Gene sequence:

>1824_bases
ATGCAAGAAGTCCACGGCAACACCCTCGGCCTCAAGCCCTCGCAGCTCCACGCCCTCCGCCGCACCTACCGCCGCCGCGT
CGACGCGCAGTCGATCGTGACGCCCGAGCTGGCGCGCCACCTCGCCGAGGTCTCCCGCGAGACCAACCGGCAGGTCGGCG
TGCTCCTCGACCGCAAGGGCGACGTGCAGGCGGTGGTGGTCGGCGACGCCCGCAAGCTCGACCTCCCGGACGTCGGCCGC
GGTCGCGCCGGCGAGAGCCGACTGCGCGGCCTGCGGCTCGTGCACACGCACCTGAACGGCGAGCCGCTCACCCGCGACGA
CCACACCGACCTGGCGCTGCTCCGGCTCGACCTCGTGGCGGCCATCGAGGTGCGCGAGGACGGCCTGCCGGGGCGGGTGC
ACTACGCCCACCTGCTGCCGGAGAACCCGCAGGGCGCCATGTGGAAGGACGAGGAGGCGCCCACCGTCCACGACCTCGCC
TACGACGCGCTCTCCGGCGCGCTCGCGCTCGAGGACGAGTTCGCCCGGGCGCGCGCGGCGCGGCGCACCGGCGGCCGGGA
GCGCGCCATCCTGGTGGGGTTCGGCGGCAAGGGGCGCGGGCGCGCCGAGGCGGAGGCCTCGCTCGAGGAGCTGAAGGAGC
TGGCCCGCACCGCCGGCGTGGAGGTGCTGGAGGCGACGCTGCAGCTCCGCCGCGACCCGGACCCGCGCTACCTCATCGGC
AAGGGGAAGCTCGAGGACATCGTCCTGCGCTCCATGCAGCGCATGGCCACGGTGATCGTGTTCGACGCCGAGCTGTCGCC
GTCGCAGGCGCGCCACATCGCCGAGGCCACCAGCCTCAAGATCCTCGACCGCACCCAGCTCATCCTCGACATCTTCGCGC
AGCGGGCCCAGTCGGCCGACGGCAAGCTGCAGGTCGAGCTGGCGCAGCTGAAGTACCTGTACCCGCGGCTGGTGGGACGC
GACGACTCGCTCTCGCGCCTCGCCGGCGGCATCGGCGGGCGCGGGCCCGGCGAGACGAAGCTCGAGATCGACCGCCGCCG
GGTGCGCGACCGGATCACCGCGCTGGAGCGGCGCATCGAGGCGCTCGGCGCCGACCGCCACCTGCGCCGCAAGCAGCGGA
ACGCCCGCGGCCTGCCGGTGCTCTCCATCGTCGGCTACACCAACGCCGGCAAGTCCACCCTGCTCAACGCGCTCACCGAC
TCGGCGGTGCTCGCCGAGGACAAGCTGTTCGCGACGCTCGACCCCACCAGCCGCCGGCTGCGCTTCCCGCGCGACCGCGA
GGTGATCATCACCGACACGGTGGGCTTCATCCGCGACCTGCCGCCCGACCTCGTGAACGCGTTCCGGGCCACGCTGGAGG
AGCTCGGCGACGCCGACCTGCTGCTGCACGTGGTGGACGCGTCGGACCCGCGGCAGGACGAGCAGATCGCGGCGGTGGAG
GAGATCCTGCGCGGCCTCGGCCTCGACGGGAAGCGCCGCCTCCTCGTGCTCAACAAGGTCGATCGCCTCCCGCCGGAGAC
GCGGGCCGCCCTCGCGCAGCGGCGCGACGCGGCGGCGGTGTCCGCGGTCACCCGGGCAGGCCTGGCCGGGCTGCTCTCGC
GCTGCGAGCAGCTGCTCTGGACCGACGGCCGGGTGGCGCTCGGCGACGTGATCGCGGCCCCCGCCGGCGAGGAGGGTGCG
GGCGCCGCCGAGCACCTCGCGGACGTGGCCGCGCCCGAGCCGCTCGCCCCGGAGCCGCCCGCGCCCGCCGCCGCCTCCGT
GCCGGGCCCCGGCGAGCCGGGCCCGCCGCGGCTGCTCCCGTCCTCGCTGCGCCGCGTCTCGTGA

Upstream 100 bases:

>100_bases
GCGCTCCCGCCCCCGCCGGCCGACCCCGCGCGGTCGGCCCCTCGCCCGCCGCAGATCGCGTCGATCCGGCGGCGGCGCCG
CGATAGACTCCCCGCAACGA

Downstream 100 bases:

>100_bases
GGCGCCCCCCGGGCCGCCGGATCTCGTGAGAGGATGCCCCGCCATGCGCCGCGCCCCGCTCGCCCTGTGCCTCGTCGCCC
TCGCCTGCTCCCGCAGCGAC

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MQEVHGNTLGLKPSQLHALRRTYRRRVDAQSIVTPELARHLAEVSRETNRQVGVLLDRKGDVQAVVVGDARKLDLPDVGR
GRAGESRLRGLRLVHTHLNGEPLTRDDHTDLALLRLDLVAAIEVREDGLPGRVHYAHLLPENPQGAMWKDEEAPTVHDLA
YDALSGALALEDEFARARAARRTGGRERAILVGFGGKGRGRAEAEASLEELKELARTAGVEVLEATLQLRRDPDPRYLIG
KGKLEDIVLRSMQRMATVIVFDAELSPSQARHIAEATSLKILDRTQLILDIFAQRAQSADGKLQVELAQLKYLYPRLVGR
DDSLSRLAGGIGGRGPGETKLEIDRRRVRDRITALERRIEALGADRHLRRKQRNARGLPVLSIVGYTNAGKSTLLNALTD
SAVLAEDKLFATLDPTSRRLRFPRDREVIITDTVGFIRDLPPDLVNAFRATLEELGDADLLLHVVDASDPRQDEQIAAVE
EILRGLGLDGKRRLLVLNKVDRLPPETRAALAQRRDAAAVSAVTRAGLAGLLSRCEQLLWTDGRVALGDVIAAPAGEEGA
GAAEHLADVAAPEPLAPEPPAPAAASVPGPGEPGPPRLLPSSLRRVS

Sequences:

>Translated_607_residues
MQEVHGNTLGLKPSQLHALRRTYRRRVDAQSIVTPELARHLAEVSRETNRQVGVLLDRKGDVQAVVVGDARKLDLPDVGR
GRAGESRLRGLRLVHTHLNGEPLTRDDHTDLALLRLDLVAAIEVREDGLPGRVHYAHLLPENPQGAMWKDEEAPTVHDLA
YDALSGALALEDEFARARAARRTGGRERAILVGFGGKGRGRAEAEASLEELKELARTAGVEVLEATLQLRRDPDPRYLIG
KGKLEDIVLRSMQRMATVIVFDAELSPSQARHIAEATSLKILDRTQLILDIFAQRAQSADGKLQVELAQLKYLYPRLVGR
DDSLSRLAGGIGGRGPGETKLEIDRRRVRDRITALERRIEALGADRHLRRKQRNARGLPVLSIVGYTNAGKSTLLNALTD
SAVLAEDKLFATLDPTSRRLRFPRDREVIITDTVGFIRDLPPDLVNAFRATLEELGDADLLLHVVDASDPRQDEQIAAVE
EILRGLGLDGKRRLLVLNKVDRLPPETRAALAQRRDAAAVSAVTRAGLAGLLSRCEQLLWTDGRVALGDVIAAPAGEEGA
GAAEHLADVAAPEPLAPEPPAPAAASVPGPGEPGPPRLLPSSLRRVS
>Mature_607_residues
MQEVHGNTLGLKPSQLHALRRTYRRRVDAQSIVTPELARHLAEVSRETNRQVGVLLDRKGDVQAVVVGDARKLDLPDVGR
GRAGESRLRGLRLVHTHLNGEPLTRDDHTDLALLRLDLVAAIEVREDGLPGRVHYAHLLPENPQGAMWKDEEAPTVHDLA
YDALSGALALEDEFARARAARRTGGRERAILVGFGGKGRGRAEAEASLEELKELARTAGVEVLEATLQLRRDPDPRYLIG
KGKLEDIVLRSMQRMATVIVFDAELSPSQARHIAEATSLKILDRTQLILDIFAQRAQSADGKLQVELAQLKYLYPRLVGR
DDSLSRLAGGIGGRGPGETKLEIDRRRVRDRITALERRIEALGADRHLRRKQRNARGLPVLSIVGYTNAGKSTLLNALTD
SAVLAEDKLFATLDPTSRRLRFPRDREVIITDTVGFIRDLPPDLVNAFRATLEELGDADLLLHVVDASDPRQDEQIAAVE
EILRGLGLDGKRRLLVLNKVDRLPPETRAALAQRRDAAAVSAVTRAGLAGLLSRCEQLLWTDGRVALGDVIAAPAGEEGA
GAAEHLADVAAPEPLAPEPPAPAAASVPGPGEPGPPRLLPSSLRRVS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=188, Percent_Identity=40.4255319148936, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310133118, Length=188, Percent_Identity=40.4255319148936, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI310124269, Length=174, Percent_Identity=41.9540229885057, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI310124267, Length=174, Percent_Identity=41.9540229885057, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI310124171, Length=174, Percent_Identity=41.9540229885057, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI310124169, Length=174, Percent_Identity=41.9540229885057, Blast_Score=132, Evalue=8e-31,
Organism=Escherichia coli, GI1790615, Length=296, Percent_Identity=49.3243243243243, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=317, Percent_Identity=29.0220820189274, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24650079, Length=366, Percent_Identity=31.9672131147541, Blast_Score=132, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 66125; Mature: 66125

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVHGNTLGLKPSQLHALRRTYRRRVDAQSIVTPELARHLAEVSRETNRQVGVLLDRKG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCC
DVQAVVVGDARKLDLPDVGRGRAGESRLRGLRLVHTHLNGEPLTRDDHTDLALLRLDLVA
CEEEEEECCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
AIEVREDGLPGRVHYAHLLPENPQGAMWKDEEAPTVHDLAYDALSGALALEDEFARARAA
HEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
RRTGGRERAILVGFGGKGRGRAEAEASLEELKELARTAGVEVLEATLQLRRDPDPRYLIG
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
KGKLEDIVLRSMQRMATVIVFDAELSPSQARHIAEATSLKILDRTQLILDIFAQRAQSAD
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLQVELAQLKYLYPRLVGRDDSLSRLAGGIGGRGPGETKLEIDRRRVRDRITALERRIE
CEEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALGADRHLRRKQRNARGLPVLSIVGYTNAGKSTLLNALTDSAVLAEDKLFATLDPTSRRL
HHCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHHC
RFPRDREVIITDTVGFIRDLPPDLVNAFRATLEELGDADLLLHVVDASDPRQDEQIAAVE
CCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
EILRGLGLDGKRRLLVLNKVDRLPPETRAALAQRRDAAAVSAVTRAGLAGLLSRCEQLLW
HHHHHCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDGRVALGDVIAAPAGEEGAGAAEHLADVAAPEPLAPEPPAPAAASVPGPGEPGPPRLLP
CCCCEEECHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SSLRRVS
HHHHHCC
>Mature Secondary Structure
MQEVHGNTLGLKPSQLHALRRTYRRRVDAQSIVTPELARHLAEVSRETNRQVGVLLDRKG
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCC
DVQAVVVGDARKLDLPDVGRGRAGESRLRGLRLVHTHLNGEPLTRDDHTDLALLRLDLVA
CEEEEEECCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
AIEVREDGLPGRVHYAHLLPENPQGAMWKDEEAPTVHDLAYDALSGALALEDEFARARAA
HEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
RRTGGRERAILVGFGGKGRGRAEAEASLEELKELARTAGVEVLEATLQLRRDPDPRYLIG
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC
KGKLEDIVLRSMQRMATVIVFDAELSPSQARHIAEATSLKILDRTQLILDIFAQRAQSAD
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLQVELAQLKYLYPRLVGRDDSLSRLAGGIGGRGPGETKLEIDRRRVRDRITALERRIE
CEEEEEHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALGADRHLRRKQRNARGLPVLSIVGYTNAGKSTLLNALTDSAVLAEDKLFATLDPTSRRL
HHCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHHC
RFPRDREVIITDTVGFIRDLPPDLVNAFRATLEELGDADLLLHVVDASDPRQDEQIAAVE
CCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
EILRGLGLDGKRRLLVLNKVDRLPPETRAALAQRRDAAAVSAVTRAGLAGLLSRCEQLLW
HHHHHCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDGRVALGDVIAAPAGEEGAGAAEHLADVAAPEPLAPEPPAPAAASVPGPGEPGPPRLLP
CCCCEEECHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
SSLRRVS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]