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The map label for this gene is arlS [H]

Identifier: 220915316

GI number: 220915316

Start: 217014

End: 218168

Strand: Reverse

Name: arlS [H]

Synonym: A2cp1_0195

Alternate gene names: 220915316

Gene position: 218168-217014 (Counterclockwise)

Preceding gene: 220915317

Following gene: 220915315

Centisome position: 4.34

GC content: 80.35

Gene sequence:

>1155_bases
ATGATCAGCAGCGCAGCGAGCCGGGGCCCGGTGCGGCCGGAGACGGTCGAGCCGGGGCGGGGGAACGGCGAGGACGGCGA
GGCCGTCCCCGGAAGACAGATCACCACCCCGCGCGCCGTGGCGGCGGCGGTGCGCCCGGAGGCGTGGCCGGCGCTCGCCA
TGTTCGGCCTGTGCGCCCTGCTCGCGGCCGAGACGGCGCTGCTCGCCGCGTTCGGCCTGGGCGGGGGCGAGGCGCTCCTG
CCGGGCGGCGACCACGACGGCGTGCTGTTCGGGGCCTCGCTCGCGGCGGCGGTGCTGGGCGGCGCGCTCGCCTCGGTGAC
GCTGGTCCGCGCGATCCGCGCCTCGCGGGCCGACCGCGACGGGCGCGCCCAGGCCGAGGCGGCGCTGCGCGCCCGCGACG
AGTTCCTCGGCCTCGCCGCCCACGAGCTGAAGACGCCGCTCACCGCGCTGTTCCTGGAGCTGGGCGCCGCCGGGCGCGAG
GCCACTCGCCGCGGCGACGAGCCCGTGCAGGGCCACCTCGCGCGCGCCGACCGCGCCGCGCGACGGCTCGCCGAGCTGGT
CTCGCGGCTGCTCGTGGACGCGCGCGCCGCCGCGGAGCCGCTCGCGCTCGAGGAGGTGGAGCTCGGATCGCTCGCGAACG
ACGCGGTGGACGCGCGCCGCGAGCTGTTCGATCGCGCCCGCTGCGACGTCACGGTGCGCGCCGAGGGCCCGGTGAGCGGG
CGCTGGGATCGCACGCGGGTCGATCGCGCGCTCGCCAGCCTGCTCGCGAACGCCGCCAAGTACGGCCAGGGGCGCCCGAT
CGAGGTGACGGTCCGCGCCGAGGGGGCCCAGGCCCGGCTCTCGGTGCGCGACCACGGCATCGGCATCCCGCCGGAGCGGC
GCGCCGCCATCTTCGACCGCTACGCGCGCGCGGTGTCGGCCCGCCACTACGGCGGCCTCGGGCTCGGCCTGTGGATCGCG
CGTCGCGAGGCGCTCGCGCTCGGCGGCACGGTCACGGTGGAGAGCCGGCCCGGCCACGGCGCCGAGTTCACGCTGCGGCT
GCCCGCCGGCGCGGCGCCGCCGCTGCGCCGCCTCCCCCGGGCGGCGGGGGGCGCGCTGGCCCGGGCGCCGGCGCGGGCGC
TGCGCTGGCTGGCGTGGCGCAGCCGCCGGTGCTAG

Upstream 100 bases:

>100_bases
GGCGCCGACCCGCGGGGGCAATTCCGCTCCCGGCTCCAGGGAGTATCCTGCCGCCCGCTCTTGTCGAGCCGTGCGACCGC
GCGGGCTCGAGGTGACCCCG

Downstream 100 bases:

>100_bases
GTTCCGCGCCCGATGCTCCTGCACCCCGCTGGCGCGCCGCGGGGGGGCCCGTCCGGCCTCAGGTTCCCGGCGTTCCTCTG
GGCGCTCCTCCACGTCCCCG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MISSAASRGPVRPETVEPGRGNGEDGEAVPGRQITTPRAVAAAVRPEAWPALAMFGLCALLAAETALLAAFGLGGGEALL
PGGDHDGVLFGASLAAAVLGGALASVTLVRAIRASRADRDGRAQAEAALRARDEFLGLAAHELKTPLTALFLELGAAGRE
ATRRGDEPVQGHLARADRAARRLAELVSRLLVDARAAAEPLALEEVELGSLANDAVDARRELFDRARCDVTVRAEGPVSG
RWDRTRVDRALASLLANAAKYGQGRPIEVTVRAEGAQARLSVRDHGIGIPPERRAAIFDRYARAVSARHYGGLGLGLWIA
RREALALGGTVTVESRPGHGAEFTLRLPAGAAPPLRRLPRAAGGALARAPARALRWLAWRSRRC

Sequences:

>Translated_384_residues
MISSAASRGPVRPETVEPGRGNGEDGEAVPGRQITTPRAVAAAVRPEAWPALAMFGLCALLAAETALLAAFGLGGGEALL
PGGDHDGVLFGASLAAAVLGGALASVTLVRAIRASRADRDGRAQAEAALRARDEFLGLAAHELKTPLTALFLELGAAGRE
ATRRGDEPVQGHLARADRAARRLAELVSRLLVDARAAAEPLALEEVELGSLANDAVDARRELFDRARCDVTVRAEGPVSG
RWDRTRVDRALASLLANAAKYGQGRPIEVTVRAEGAQARLSVRDHGIGIPPERRAAIFDRYARAVSARHYGGLGLGLWIA
RREALALGGTVTVESRPGHGAEFTLRLPAGAAPPLRRLPRAAGGALARAPARALRWLAWRSRRC
>Mature_384_residues
MISSAASRGPVRPETVEPGRGNGEDGEAVPGRQITTPRAVAAAVRPEAWPALAMFGLCALLAAETALLAAFGLGGGEALL
PGGDHDGVLFGASLAAAVLGGALASVTLVRAIRASRADRDGRAQAEAALRARDEFLGLAAHELKTPLTALFLELGAAGRE
ATRRGDEPVQGHLARADRAARRLAELVSRLLVDARAAAEPLALEEVELGSLANDAVDARRELFDRARCDVTVRAEGPVSG
RWDRTRVDRALASLLANAAKYGQGRPIEVTVRAEGAQARLSVRDHGIGIPPERRAAIFDRYARAVSARHYGGLGLGLWIA
RREALALGGTVTVESRPGHGAEFTLRLPAGAAPPLRRLPRAAGGALARAPARALRWLAWRSRRC

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=27.9166666666667, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=31.5126050420168, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=28.4090909090909, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=30.5439330543933, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790436, Length=296, Percent_Identity=27.3648648648649, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=29.7520661157025, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.6324786324786, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=30.3418803418803, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=30.1724137931034, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=29.1304347826087, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=25.2918287937743, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40314; Mature: 40314

Theoretical pI: Translated: 11.36; Mature: 11.36

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSAASRGPVRPETVEPGRGNGEDGEAVPGRQITTPRAVAAAVRPEAWPALAMFGLCAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
LAAETALLAAFGLGGGEALLPGGDHDGVLFGASLAAAVLGGALASVTLVRAIRASRADRD
HHHHHHHHHHHCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GRAQAEAALRARDEFLGLAAHELKTPLTALFLELGAAGREATRRGDEPVQGHLARADRAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHH
RRLAELVSRLLVDARAAAEPLALEEVELGSLANDAVDARRELFDRARCDVTVRAEGPVSG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
RWDRTRVDRALASLLANAAKYGQGRPIEVTVRAEGAQARLSVRDHGIGIPPERRAAIFDR
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHCCCCCCCHHHHHHHHH
YARAVSARHYGGLGLGLWIARREALALGGTVTVESRPGHGAEFTLRLPAGAAPPLRRLPR
HHHHHHHHCCCCCHHHHHHHHHHHHEECCEEEEECCCCCCCEEEEECCCCCCCHHHHCCH
AAGGALARAPARALRWLAWRSRRC
HHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MISSAASRGPVRPETVEPGRGNGEDGEAVPGRQITTPRAVAAAVRPEAWPALAMFGLCAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
LAAETALLAAFGLGGGEALLPGGDHDGVLFGASLAAAVLGGALASVTLVRAIRASRADRD
HHHHHHHHHHHCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GRAQAEAALRARDEFLGLAAHELKTPLTALFLELGAAGREATRRGDEPVQGHLARADRAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHH
RRLAELVSRLLVDARAAAEPLALEEVELGSLANDAVDARRELFDRARCDVTVRAEGPVSG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
RWDRTRVDRALASLLANAAKYGQGRPIEVTVRAEGAQARLSVRDHGIGIPPERRAAIFDR
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEHHCCCCCCCHHHHHHHHH
YARAVSARHYGGLGLGLWIARREALALGGTVTVESRPGHGAEFTLRLPAGAAPPLRRLPR
HHHHHHHHCCCCCHHHHHHHHHHHHEECCEEEEECCCCCCCEEEEECCCCCCCHHHHCCH
AAGGALARAPARALRWLAWRSRRC
HHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA