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The map label for this gene is yuxL [H]

Identifier: 220915253

GI number: 220915253

Start: 149726

End: 151750

Strand: Reverse

Name: yuxL [H]

Synonym: A2cp1_0132

Alternate gene names: 220915253

Gene position: 151750-149726 (Counterclockwise)

Preceding gene: 220915255

Following gene: 220915252

Centisome position: 3.02

GC content: 76.2

Gene sequence:

>2025_bases
ATGCTCACCGCCGCGCTCGTCGCGCTCGCCCTCGCATCGGTCCCCCGCCCCTTCACCGTCGATGACCTGCTCGCGCTCGA
GCGCGCGGGGGACGCGGCCGTCTCGCCGGACGGCGCCAGCGTCGCGTACACCGTCGCCACCTCGTCGGCGGGCGGCGAGA
AGCTCGTCTCGGCGCTGCACCTCGTCCCCGCCGCGGGCGGCGCCGCCCGCCGGCTCACGTTCGGCGAGGAGCGGGTGACC
TCGCCGGCGTTCTCGCCCGACGGGCGGCGGATCGCGTTCCTCTCCAACCGCAAGGGCGGCACGCAGGCGTGGGTGCTCGA
CCTCCAGGGCGGCGAGGCCCGGCGGGTGACGGACCTGCCCGGCGGCGTCTCCGAGCTCCGCTTCACCCCGGACGGCGCCG
CGCTGGTCGTCGCGAGCGACGTGGACCCGGCCTGCGGCGCCGACGCGGCCTGCAACCGGAAGGCGGACGCGGCCGCCGAG
GTCCGCCCGCACCTCACCGACCGGCTCCTGTTCCGGCACTGGAACGAGTGGCGCGAGCGCGTGCGCACGCACCTCGTCCG
CGTGCCGCTCGACGGCGGCCCCGCGGTGGACCTCACCCCGGGCGACCGCGACGCTCCGCCGGTGCAGCGCGGCTCGGGCG
ACGACCTGGCCTTCTCGCCGGACGGGAAGACGCTCTACTACGTGGCGGTCTCGGATCCGGTGGAGGCCACCTCGACGAAC
GGGGACGTGTACGCGGTCCCGCTCGCCGGCGGGACGCCCCGCCGCGTCACCACCGCGCCGGGCTGGGACGGCTCGCCCCG
CCCGTCGCCGGACGGCAAGCGGCTTGCGTGGCTGGCCCAGCCGCGCGCGGGCTACGAGGCCGACCGCTTCCACGTGATGG
TGGCGGCGGCGGACGGGTCGGGCGCGCGCGACCTCACCGCCGGCTTCGACCGCTCCGCGGCCGATCTCGAGTGGGCCCGC
GGCGGCAAGGCGCTCCGGTTCACCGCCGAGAGCGAGGGCGTCCACGCGGTCTACGAGGTGGACCTCGCCGGCAAGGTGAC
CGAGCTGTACCGCGGCCGGAACCTCGCCCGCGTGAGCTGGTCGCGCGACGGCGCGCGCCTCGCCGCGCTGGTGGACGGGC
TGGCGGCGCCGCCGGAGGTGGCGGTGCTCGAGCCGGGCGCGCGCGGGCCGCAGCCGCGCCTGCTCACTGGCTTCGGCGCG
AAGGGGCTCACCGGGGTCGCGCTCGGCGAGGTCCGCCCCCTCGCCGCCACCGGCAAGGACGGACAGGCGCTGCACGGGTG
GATGGTGCTGCCGCCGGGCCACCGCGACGGCCAGCGGCACCCCGCGGTGGTGCTCGTCCACGGCGGCCCGCAGGGCGCCT
GGAACGACGCCTGGAGCTTCCGCTGGAACCCCATGCTGTACGCCGCCCGGGGCTGGACGGTGGTGCTGCCCAACCCGCGC
GGCTCGACCGGCTTCGGTCAGGCCTACACCGACGCCGTCCGGGGGAACTGGGGCGGCACCCCGTACGACGACATCATGCG
GCTCACCGACGCGGCCGTCGCCACCGGCGCCGCCGACGGGGACCGGATGTGCGCCGCCGGCGCGAGCTACGGCGGGTACA
TGGTGAACTGGATCAACGGCCAGACCGACCGGTTCCGCTGCCTGGTGGCGCACGCGGGCAACTTCGACCTGCGCATGGCG
TACTACGACACCGAGGAGCTCTGGTTCCCCGAATGGGAGCTGGGGCGTCCGTGGGAGGCGTCGGAGGCGTTCGAGCGCTG
GTCGCCGAGCGCGTTCGTGGGGCGGTGGCGGACGCCGACGCTGATCTCGCACGGCGAGAAGGACTTCCGCGTCACCGTGA
CGCAGGGCTTCGCCGCGTTCACGGCGCTCCAGCGGCGCGGGGTCCCCTCGCGGCTGATGGTGTTCCCGGACGAGGGGCAC
TGGGTGCTGAAGCCGCGCAACGCGAAGGTGTTCCACGACGAGGTGCTCGGCTGGATCGGCCGGTGGCTGGAATCGCCTGC
CCCGCAGGCGAGCGCGCCGCGGTGA

Upstream 100 bases:

>100_bases
GCATGCGCTCGCCGCGAGAGTATCCCGGCGCCGCCGGACCCGGAAAGTCCCGGCCGCATCGGGATCGCGCGCCGGTGCGA
CGTGGTAGAAAGTCCGCCCC

Downstream 100 bases:

>100_bases
AGGCCGGGACCTTGTCGCCCCCGAACCCCCTGCTATAGTCCGGACCCGCCGTGCTCGACTGGCTTCACAACATGATGTCC
CGCGATCTCGCGATCGACCT

Product: peptidase S9 prolyl oligopeptidase active site domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MLTAALVALALASVPRPFTVDDLLALERAGDAAVSPDGASVAYTVATSSAGGEKLVSALHLVPAAGGAARRLTFGEERVT
SPAFSPDGRRIAFLSNRKGGTQAWVLDLQGGEARRVTDLPGGVSELRFTPDGAALVVASDVDPACGADAACNRKADAAAE
VRPHLTDRLLFRHWNEWRERVRTHLVRVPLDGGPAVDLTPGDRDAPPVQRGSGDDLAFSPDGKTLYYVAVSDPVEATSTN
GDVYAVPLAGGTPRRVTTAPGWDGSPRPSPDGKRLAWLAQPRAGYEADRFHVMVAAADGSGARDLTAGFDRSAADLEWAR
GGKALRFTAESEGVHAVYEVDLAGKVTELYRGRNLARVSWSRDGARLAALVDGLAAPPEVAVLEPGARGPQPRLLTGFGA
KGLTGVALGEVRPLAATGKDGQALHGWMVLPPGHRDGQRHPAVVLVHGGPQGAWNDAWSFRWNPMLYAARGWTVVLPNPR
GSTGFGQAYTDAVRGNWGGTPYDDIMRLTDAAVATGAADGDRMCAAGASYGGYMVNWINGQTDRFRCLVAHAGNFDLRMA
YYDTEELWFPEWELGRPWEASEAFERWSPSAFVGRWRTPTLISHGEKDFRVTVTQGFAAFTALQRRGVPSRLMVFPDEGH
WVLKPRNAKVFHDEVLGWIGRWLESPAPQASAPR

Sequences:

>Translated_674_residues
MLTAALVALALASVPRPFTVDDLLALERAGDAAVSPDGASVAYTVATSSAGGEKLVSALHLVPAAGGAARRLTFGEERVT
SPAFSPDGRRIAFLSNRKGGTQAWVLDLQGGEARRVTDLPGGVSELRFTPDGAALVVASDVDPACGADAACNRKADAAAE
VRPHLTDRLLFRHWNEWRERVRTHLVRVPLDGGPAVDLTPGDRDAPPVQRGSGDDLAFSPDGKTLYYVAVSDPVEATSTN
GDVYAVPLAGGTPRRVTTAPGWDGSPRPSPDGKRLAWLAQPRAGYEADRFHVMVAAADGSGARDLTAGFDRSAADLEWAR
GGKALRFTAESEGVHAVYEVDLAGKVTELYRGRNLARVSWSRDGARLAALVDGLAAPPEVAVLEPGARGPQPRLLTGFGA
KGLTGVALGEVRPLAATGKDGQALHGWMVLPPGHRDGQRHPAVVLVHGGPQGAWNDAWSFRWNPMLYAARGWTVVLPNPR
GSTGFGQAYTDAVRGNWGGTPYDDIMRLTDAAVATGAADGDRMCAAGASYGGYMVNWINGQTDRFRCLVAHAGNFDLRMA
YYDTEELWFPEWELGRPWEASEAFERWSPSAFVGRWRTPTLISHGEKDFRVTVTQGFAAFTALQRRGVPSRLMVFPDEGH
WVLKPRNAKVFHDEVLGWIGRWLESPAPQASAPR
>Mature_674_residues
MLTAALVALALASVPRPFTVDDLLALERAGDAAVSPDGASVAYTVATSSAGGEKLVSALHLVPAAGGAARRLTFGEERVT
SPAFSPDGRRIAFLSNRKGGTQAWVLDLQGGEARRVTDLPGGVSELRFTPDGAALVVASDVDPACGADAACNRKADAAAE
VRPHLTDRLLFRHWNEWRERVRTHLVRVPLDGGPAVDLTPGDRDAPPVQRGSGDDLAFSPDGKTLYYVAVSDPVEATSTN
GDVYAVPLAGGTPRRVTTAPGWDGSPRPSPDGKRLAWLAQPRAGYEADRFHVMVAAADGSGARDLTAGFDRSAADLEWAR
GGKALRFTAESEGVHAVYEVDLAGKVTELYRGRNLARVSWSRDGARLAALVDGLAAPPEVAVLEPGARGPQPRLLTGFGA
KGLTGVALGEVRPLAATGKDGQALHGWMVLPPGHRDGQRHPAVVLVHGGPQGAWNDAWSFRWNPMLYAARGWTVVLPNPR
GSTGFGQAYTDAVRGNWGGTPYDDIMRLTDAAVATGAADGDRMCAAGASYGGYMVNWINGQTDRFRCLVAHAGNFDLRMA
YYDTEELWFPEWELGRPWEASEAFERWSPSAFVGRWRTPTLISHGEKDFRVTVTQGFAAFTALQRRGVPSRLMVFPDEGH
WVLKPRNAKVFHDEVLGWIGRWLESPAPQASAPR

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=445, Percent_Identity=25.1685393258427, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144537, Length=230, Percent_Identity=30, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144540, Length=230, Percent_Identity=30, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17552908, Length=216, Percent_Identity=28.7037037037037, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25149159, Length=235, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144543, Length=91, Percent_Identity=40.6593406593407, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24582257, Length=248, Percent_Identity=26.2096774193548, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 72179; Mature: 72179

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAALVALALASVPRPFTVDDLLALERAGDAAVSPDGASVAYTVATSSAGGEKLVSALH
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHH
LVPAAGGAARRLTFGEERVTSPAFSPDGRRIAFLSNRKGGTQAWVLDLQGGEARRVTDLP
HHCCCCCCEEEEECCHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEECCC
GGVSELRFTPDGAALVVASDVDPACGADAACNRKADAAAEVRPHLTDRLLFRHWNEWRER
CCHHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHH
VRTHLVRVPLDGGPAVDLTPGDRDAPPVQRGSGDDLAFSPDGKTLYYVAVSDPVEATSTN
HHHEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCC
GDVYAVPLAGGTPRRVTTAPGWDGSPRPSPDGKRLAWLAQPRAGYEADRFHVMVAAADGS
CCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCC
GARDLTAGFDRSAADLEWARGGKALRFTAESEGVHAVYEVDLAGKVTELYRGRNLARVSW
CCCCHHCCCCCCCCCCHHHCCCCEEEEEECCCCEEEEEEEECCCHHHHHHCCCCEEEEEE
SRDGARLAALVDGLAAPPEVAVLEPGARGPQPRLLTGFGAKGLTGVALGEVRPLAATGKD
CCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCEEEECCCCEEEECCCC
GQALHGWMVLPPGHRDGQRHPAVVLVHGGPQGAWNDAWSFRWNPMLYAARGWTVVLPNPR
CCEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCEEEEECCCEEEECCCC
GSTGFGQAYTDAVRGNWGGTPYDDIMRLTDAAVATGAADGDRMCAAGASYGGYMVNWING
CCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECC
QTDRFRCLVAHAGNFDLRMAYYDTEELWFPEWELGRPWEASEAFERWSPSAFVGRWRTPT
CCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCH
LISHGEKDFRVTVTQGFAAFTALQRRGVPSRLMVFPDEGHWVLKPRNAKVFHDEVLGWIG
HHHCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCEEHHHHHHHHHH
RWLESPAPQASAPR
HHHCCCCCCCCCCC
>Mature Secondary Structure
MLTAALVALALASVPRPFTVDDLLALERAGDAAVSPDGASVAYTVATSSAGGEKLVSALH
CHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHH
LVPAAGGAARRLTFGEERVTSPAFSPDGRRIAFLSNRKGGTQAWVLDLQGGEARRVTDLP
HHCCCCCCEEEEECCHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEECCC
GGVSELRFTPDGAALVVASDVDPACGADAACNRKADAAAEVRPHLTDRLLFRHWNEWRER
CCHHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHH
VRTHLVRVPLDGGPAVDLTPGDRDAPPVQRGSGDDLAFSPDGKTLYYVAVSDPVEATSTN
HHHEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCC
GDVYAVPLAGGTPRRVTTAPGWDGSPRPSPDGKRLAWLAQPRAGYEADRFHVMVAAADGS
CCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCC
GARDLTAGFDRSAADLEWARGGKALRFTAESEGVHAVYEVDLAGKVTELYRGRNLARVSW
CCCCHHCCCCCCCCCCHHHCCCCEEEEEECCCCEEEEEEEECCCHHHHHHCCCCEEEEEE
SRDGARLAALVDGLAAPPEVAVLEPGARGPQPRLLTGFGAKGLTGVALGEVRPLAATGKD
CCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCCEEEECCCCEEEECCCC
GQALHGWMVLPPGHRDGQRHPAVVLVHGGPQGAWNDAWSFRWNPMLYAARGWTVVLPNPR
CCEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCEEEEECCCEEEECCCC
GSTGFGQAYTDAVRGNWGGTPYDDIMRLTDAAVATGAADGDRMCAAGASYGGYMVNWING
CCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECC
QTDRFRCLVAHAGNFDLRMAYYDTEELWFPEWELGRPWEASEAFERWSPSAFVGRWRTPT
CCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCH
LISHGEKDFRVTVTQGFAAFTALQRRGVPSRLMVFPDEGHWVLKPRNAKVFHDEVLGWIG
HHHCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCEEHHHHHHHHHH
RWLESPAPQASAPR
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]