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The map label for this gene is degP [H]

Identifier: 220915212

GI number: 220915212

Start: 101522

End: 102946

Strand: Reverse

Name: degP [H]

Synonym: A2cp1_0091

Alternate gene names: 220915212

Gene position: 102946-101522 (Counterclockwise)

Preceding gene: 220915213

Following gene: 220915211

Centisome position: 2.05

GC content: 76.28

Gene sequence:

>1425_bases
GTGGTGAGGTCCCGCCGCAGCAGCAGCCGTAGCGCCGTTCGCGGCGCCGGGCGCGCCCTCGCGCTCGCCGCCGCGCTCGC
CGCCGGGCTCCCGGCGCCCGCCGCGGCCCGGCCCCCCGCCGCGCTCCCGCGCGCCGACGAGCGCCCCTCCGCGAACCGCC
GCACGCCGGTGGTGATCGCGGTGGAGAAGGTGCGCGGCGCGGTGGTGAACGTCTCCGCAGAGGAGCTGGTCCGCATCCGC
GTCCCCTCGCAGCCGCGCGGCGGCTCGATGGGCGACCTGCTGTTCGGCGACCTGTTCGAGCGGCCGCGCTACCGCAAGGG
CTACGCGACCACCTCGCTCGGCTCGGGCGTGATCGTGTCGCCCGACGGCTACGTGCTCACCAACAACCACGTGGTGGAGC
GCGGCGCCCGCTTCCGGGTGGGCCTGCTCGACGGCCGCGAGCTCATGGCGAAGGTGGTCGGCACCGACCCGTCGTCCGAC
CTGGCGGTGCTGAAGCTCGACACCCGCGAGAAGCTCCCCTACGTCACCACCGGCCGCTCCGACGACCTGCTCATCGGCGA
GACGGTGATCGCCATCGGCAACCCGTTCGGCCTCGCGCACACGGTCACCACCGGCGTGGTCTCGGCGGTGCACCGCAACT
TCAAGGCGGGCGAGCGGATGATGTTCGACTTCATCCAGACCGACGCCTCCATCAACCCCGGCAACTCCGGCGGGCCGCTG
CTCGACATCGACGGGCGGCTGGTGGGCGTGAACACCGCCATCCTGGGCGACCGCAGCGCCGGCATCGGCTTCGCGATCCC
CATCGACCGCGCGCGCCGCGTCGCCGAGGACCTGATCGCGCACGGCGAGGTGCGCGAGGGTTACCTGGGCGTCTCGGTGG
ACGACCTGCCTCGCAAGGACGGCACGGTGGACGGCGGGTCCGGCGGCGTGCGCGTCACCGGGGTGGACCCGGGCTCGCCC
GGCGAGCGCGCCGGCGTCCGCGCCGGCGACGTGGTGGAGGCGGTGGACGGGACCCCGCCCGGCAGCGCCGCGGAGCTCCT
GTTCCGCCTGCGCGACCTCCCCATCGGCCGCGCCGCGCGGCTCGACCTGTCGCGCCGCGGCGCGCGCGTCCAGGCGGCCG
TCACCGCGGTGGAGCTCACCCCGCAGCGCGCCGCCGAGCTGGTGCAGCGCCGCGTGGGGCTGCGCGTCTCCGAGGAGCGC
GTCTCCGGGGGCACGCTGGTGGTGGTGCGCAGCGTGACCGGCCGCTCGCCCGCCGCCGAGGCCGGGTTGCAGCCGGGCGA
CCTGGTGCGCGAGGTGAACTCGTCCGAGGTCTCCTCGGTGGCGGCGTTCCAGCGCGCCGCCGCCCGCGCCCGCCGCGGCG
GCCGGCTCGTGCTGCTCGTCCAGCGCGGCTACGCCGCCGACCGCATCGCCTTCGACTTCGACTAG

Upstream 100 bases:

>100_bases
CCGGATCTCGCCGATCAGGCGATGCCCATCGAGGCGTCGATGAGCGGCGTCGAGGAGCCGGACGATCTCGACGACGACGA
GCCCGAGGAGGACGTCGGAG

Downstream 100 bases:

>100_bases
ATCGTCCGGGAGGACCCGACCATGGCCGACGAGAAGCAGCCCGCGCCCATCGACTTCTACACGTTCGTGCTGTCGCTCGG
CTCCTCCGCGTTCGTCCACC

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MVRSRRSSSRSAVRGAGRALALAAALAAGLPAPAAARPPAALPRADERPSANRRTPVVIAVEKVRGAVVNVSAEELVRIR
VPSQPRGGSMGDLLFGDLFERPRYRKGYATTSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGRELMAKVVGTDPSSD
LAVLKLDTREKLPYVTTGRSDDLLIGETVIAIGNPFGLAHTVTTGVVSAVHRNFKAGERMMFDFIQTDASINPGNSGGPL
LDIDGRLVGVNTAILGDRSAGIGFAIPIDRARRVAEDLIAHGEVREGYLGVSVDDLPRKDGTVDGGSGGVRVTGVDPGSP
GERAGVRAGDVVEAVDGTPPGSAAELLFRLRDLPIGRAARLDLSRRGARVQAAVTAVELTPQRAAELVQRRVGLRVSEER
VSGGTLVVVRSVTGRSPAAEAGLQPGDLVREVNSSEVSSVAAFQRAAARARRGGRLVLLVQRGYAADRIAFDFD

Sequences:

>Translated_474_residues
MVRSRRSSSRSAVRGAGRALALAAALAAGLPAPAAARPPAALPRADERPSANRRTPVVIAVEKVRGAVVNVSAEELVRIR
VPSQPRGGSMGDLLFGDLFERPRYRKGYATTSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGRELMAKVVGTDPSSD
LAVLKLDTREKLPYVTTGRSDDLLIGETVIAIGNPFGLAHTVTTGVVSAVHRNFKAGERMMFDFIQTDASINPGNSGGPL
LDIDGRLVGVNTAILGDRSAGIGFAIPIDRARRVAEDLIAHGEVREGYLGVSVDDLPRKDGTVDGGSGGVRVTGVDPGSP
GERAGVRAGDVVEAVDGTPPGSAAELLFRLRDLPIGRAARLDLSRRGARVQAAVTAVELTPQRAAELVQRRVGLRVSEER
VSGGTLVVVRSVTGRSPAAEAGLQPGDLVREVNSSEVSSVAAFQRAAARARRGGRLVLLVQRGYAADRIAFDFD
>Mature_474_residues
MVRSRRSSSRSAVRGAGRALALAAALAAGLPAPAAARPPAALPRADERPSANRRTPVVIAVEKVRGAVVNVSAEELVRIR
VPSQPRGGSMGDLLFGDLFERPRYRKGYATTSLGSGVIVSPDGYVLTNNHVVERGARFRVGLLDGRELMAKVVGTDPSSD
LAVLKLDTREKLPYVTTGRSDDLLIGETVIAIGNPFGLAHTVTTGVVSAVHRNFKAGERMMFDFIQTDASINPGNSGGPL
LDIDGRLVGVNTAILGDRSAGIGFAIPIDRARRVAEDLIAHGEVREGYLGVSVDDLPRKDGTVDGGSGGVRVTGVDPGSP
GERAGVRAGDVVEAVDGTPPGSAAELLFRLRDLPIGRAARLDLSRRGARVQAAVTAVELTPQRAAELVQRRVGLRVSEER
VSGGTLVVVRSVTGRSPAAEAGLQPGDLVREVNSSEVSSVAAFQRAAARARRGGRLVLLVQRGYAADRIAFDFD

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=256, Percent_Identity=39.0625, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI22129776, Length=269, Percent_Identity=37.546468401487, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI7019477, Length=263, Percent_Identity=36.5019011406844, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308541, Length=263, Percent_Identity=37.2623574144487, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1789629, Length=443, Percent_Identity=38.1489841986456, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786356, Length=461, Percent_Identity=34.056399132321, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1789630, Length=292, Percent_Identity=36.3013698630137, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24646839, Length=265, Percent_Identity=34.7169811320755, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49734; Mature: 49734

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSRRSSSRSAVRGAGRALALAAALAAGLPAPAAARPPAALPRADERPSANRRTPVVIA
CCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VEKVRGAVVNVSAEELVRIRVPSQPRGGSMGDLLFGDLFERPRYRKGYATTSLGSGVIVS
EECCCCEEEEECHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
PDGYVLTNNHVVERGARFRVGLLDGRELMAKVVGTDPSSDLAVLKLDTREKLPYVTTGRS
CCCEEEECCHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCC
DDLLIGETVIAIGNPFGLAHTVTTGVVSAVHRNFKAGERMMFDFIQTDASINPGNSGGPL
CCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
LDIDGRLVGVNTAILGDRSAGIGFAIPIDRARRVAEDLIAHGEVREGYLGVSVDDLPRKD
EEECCEEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEECCHHCCCCCC
GTVDGGSGGVRVTGVDPGSPGERAGVRAGDVVEAVDGTPPGSAAELLFRLRDLPIGRAAR
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHC
LDLSRRGARVQAAVTAVELTPQRAAELVQRRVGLRVSEERVSGGTLVVVRSVTGRSPAAE
CCHHHCCCEEEEEEEEEEECHHHHHHHHHHHHCCEEEHHHCCCCEEEEEEECCCCCCHHH
AGLQPGDLVREVNSSEVSSVAAFQRAAARARRGGRLVLLVQRGYAADRIAFDFD
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECC
>Mature Secondary Structure
MVRSRRSSSRSAVRGAGRALALAAALAAGLPAPAAARPPAALPRADERPSANRRTPVVIA
CCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
VEKVRGAVVNVSAEELVRIRVPSQPRGGSMGDLLFGDLFERPRYRKGYATTSLGSGVIVS
EECCCCEEEEECHHHEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEC
PDGYVLTNNHVVERGARFRVGLLDGRELMAKVVGTDPSSDLAVLKLDTREKLPYVTTGRS
CCCEEEECCHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCC
DDLLIGETVIAIGNPFGLAHTVTTGVVSAVHRNFKAGERMMFDFIQTDASINPGNSGGPL
CCEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
LDIDGRLVGVNTAILGDRSAGIGFAIPIDRARRVAEDLIAHGEVREGYLGVSVDDLPRKD
EEECCEEEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEECCHHCCCCCC
GTVDGGSGGVRVTGVDPGSPGERAGVRAGDVVEAVDGTPPGSAAELLFRLRDLPIGRAAR
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHC
LDLSRRGARVQAAVTAVELTPQRAAELVQRRVGLRVSEERVSGGTLVVVRSVTGRSPAAE
CCHHHCCCEEEEEEEEEEECHHHHHHHHHHHHCCEEEHHHCCCCEEEEEEECCCCCCHHH
AGLQPGDLVREVNSSEVSSVAAFQRAAARARRGGRLVLLVQRGYAADRIAFDFD
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]