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The map label for this gene is oxaA [H]

Identifier: 220905229

GI number: 220905229

Start: 2372218

End: 2373864

Strand: Reverse

Name: oxaA [H]

Synonym: Ddes_1967

Alternate gene names: 220905229

Gene position: 2373864-2372218 (Counterclockwise)

Preceding gene: 220905230

Following gene: 220905228

Centisome position: 82.61

GC content: 58.77

Gene sequence:

>1647_bases
ATGCAAGACGGTAAAAATCTTCTCATTGCCATTGTTCTTTGTCTTATTGTCATTGTTGGCTGGGGCTATCTGGCCGAGTA
TATGGGCTGGGCCACCCGGCCTGCCCCGGTGGCGCAGCAAAGCCAGGACCAGCAGGCCGCCCATCCGCAGCCGCAGGCCC
AGACGCAGGCCGCGCCCGCACAGGCGAGCCTGCCCGTCTTTACGCCAGCGCCCGGGCGCGACCTTACTGTGGACACCCCT
CTTTACGAAGCCGTGGTCTACAGTGGCGGCGGCGCGCTGCGGTCGTTCAAGCTGAAAAAATACCAGGTAGGCCTTGCGGC
CGACTCGCCCCAGGTGAACATGGTTGATCCCAAGAGCGCCCAGGTGGCTCCTCTGGGGCTTGTCATCAACAGCCAGCCCT
CATGGAGTACGGGCCAGTGGTCTATGGACACCGGCGAGAACGGGCTTGCTCTTGAACAGGGCCAGCAGGGAACGCTGCGC
CTCGTGGGCGAAGTGGACAACCTGCGTGTGGTGCGCGAAATGACCTTCAGCGCCACCAACTATCTTATCCGCGAAAAAAT
CCGTGTGGTGAACCAGACCCAGCAGGCCCGCAGTGTGCGTGTGAGCTATACTGTGGCCGCTGATGCCAGCAATGCCGCCG
GCGACCGCTACGACGCCATGCGCGTGGCGTGGGACAACGACGGCAGCCTCAAGGAAGAAAGCTCGGCCAGTACCCTTGAA
AGCACCGGTGTGCAGGCTGTGGGTAAAATTTACTGGGCCGGGGCCATGAGCACGTATTTTCTTGCGGCCGTGCTGCCCGG
CGATGTGAATAACGTGACCGTCAAGGGCGTAATGCAGCAGAACGTGTACCGCACCGCCGTGGAAGAGCAGGAAACCCTGC
TCGGCCCCGGACAGGAAAAAGAGCTTTCTGTTTCCTACTGGGTTGGTCCCAAGGTGCGCTCCGAACTGCAGGCCGTTTCG
CCCCAGCTTGCCAAGAGCGTTGATCTGGGCTTTTTCCACATCATTGCCAAGGGCCTTCTGTGGCTGCTGGAATTTTTCCA
CAAGTATGTGCACAACTGGGGTCTGGCAATCATTCTGCTGACCGTGCTCATCAAGGCCGCCTTCTGGCCCCTGACGGCCA
AGAGCTACGCCTCTATGGAAAAGATGAAGAAGCTCCAGCCGCACATGATGGAGATTCGTGAAAAGTTCAAGGACAACAAG
GAACAGATGAACAAAGAGGTCATGGCCCTCTACAAGACCTATGGCGTCAACCCCGCCAGCGGCTGTGTGCCCATCCTCAT
CCAGTTGCCCGTATTCTTTGGCCTGTACCAGGCCCTGCTCACATCCATCGAGCTGCGTCATGCGCCCTTTATCACCTATC
TGCCCGGAACGGACATCCTGTGGCTGGCTGACCTGTCCACCAAGGATCCCCTGTACATTACGCCCGTGATCATGGGCCTG
ACCATGTTTTTGCAGCAGCGGATGAGCCCCCCGGCCACAGATCCCACGCAGCAGAAGATCATGATGTTTCTTCCCCTTAT
CTTTACGGCGCTTTTCCTGAACTTCCCTTCGGGTCTGGTGCTGTACTGGCTGGTCAACAACGTGCTTTCCATAGCCCAGC
AGCAGATGATGATCCGGAAGTTCAAGGCCAACGCCGCCGCGAAATAG

Upstream 100 bases:

>100_bases
TGGCCCGCTGTCACCCTTGGGGCGGTTCGGGTTATGACCCTGTTCCACCATCACGACGTCGCCGTGACGTTCCGCCATTG
TCCCAGGAGTGAGCGCCCTC

Downstream 100 bases:

>100_bases
CCGCAGCGACGGCTTGCGATACCTATTGGAACGAGGATGATTATGGAAGGGTTCAAGGAATTCCAGGGCAAAGACCTGGA
CAGCGCCATAGAGGAAGCCT

Product: YidC translocase/secretase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MQDGKNLLIAIVLCLIVIVGWGYLAEYMGWATRPAPVAQQSQDQQAAHPQPQAQTQAAPAQASLPVFTPAPGRDLTVDTP
LYEAVVYSGGGALRSFKLKKYQVGLAADSPQVNMVDPKSAQVAPLGLVINSQPSWSTGQWSMDTGENGLALEQGQQGTLR
LVGEVDNLRVVREMTFSATNYLIREKIRVVNQTQQARSVRVSYTVAADASNAAGDRYDAMRVAWDNDGSLKEESSASTLE
STGVQAVGKIYWAGAMSTYFLAAVLPGDVNNVTVKGVMQQNVYRTAVEEQETLLGPGQEKELSVSYWVGPKVRSELQAVS
PQLAKSVDLGFFHIIAKGLLWLLEFFHKYVHNWGLAIILLTVLIKAAFWPLTAKSYASMEKMKKLQPHMMEIREKFKDNK
EQMNKEVMALYKTYGVNPASGCVPILIQLPVFFGLYQALLTSIELRHAPFITYLPGTDILWLADLSTKDPLYITPVIMGL
TMFLQQRMSPPATDPTQQKIMMFLPLIFTALFLNFPSGLVLYWLVNNVLSIAQQQMMIRKFKANAAAK

Sequences:

>Translated_548_residues
MQDGKNLLIAIVLCLIVIVGWGYLAEYMGWATRPAPVAQQSQDQQAAHPQPQAQTQAAPAQASLPVFTPAPGRDLTVDTP
LYEAVVYSGGGALRSFKLKKYQVGLAADSPQVNMVDPKSAQVAPLGLVINSQPSWSTGQWSMDTGENGLALEQGQQGTLR
LVGEVDNLRVVREMTFSATNYLIREKIRVVNQTQQARSVRVSYTVAADASNAAGDRYDAMRVAWDNDGSLKEESSASTLE
STGVQAVGKIYWAGAMSTYFLAAVLPGDVNNVTVKGVMQQNVYRTAVEEQETLLGPGQEKELSVSYWVGPKVRSELQAVS
PQLAKSVDLGFFHIIAKGLLWLLEFFHKYVHNWGLAIILLTVLIKAAFWPLTAKSYASMEKMKKLQPHMMEIREKFKDNK
EQMNKEVMALYKTYGVNPASGCVPILIQLPVFFGLYQALLTSIELRHAPFITYLPGTDILWLADLSTKDPLYITPVIMGL
TMFLQQRMSPPATDPTQQKIMMFLPLIFTALFLNFPSGLVLYWLVNNVLSIAQQQMMIRKFKANAAAK
>Mature_548_residues
MQDGKNLLIAIVLCLIVIVGWGYLAEYMGWATRPAPVAQQSQDQQAAHPQPQAQTQAAPAQASLPVFTPAPGRDLTVDTP
LYEAVVYSGGGALRSFKLKKYQVGLAADSPQVNMVDPKSAQVAPLGLVINSQPSWSTGQWSMDTGENGLALEQGQQGTLR
LVGEVDNLRVVREMTFSATNYLIREKIRVVNQTQQARSVRVSYTVAADASNAAGDRYDAMRVAWDNDGSLKEESSASTLE
STGVQAVGKIYWAGAMSTYFLAAVLPGDVNNVTVKGVMQQNVYRTAVEEQETLLGPGQEKELSVSYWVGPKVRSELQAVS
PQLAKSVDLGFFHIIAKGLLWLLEFFHKYVHNWGLAIILLTVLIKAAFWPLTAKSYASMEKMKKLQPHMMEIREKFKDNK
EQMNKEVMALYKTYGVNPASGCVPILIQLPVFFGLYQALLTSIELRHAPFITYLPGTDILWLADLSTKDPLYITPVIMGL
TMFLQQRMSPPATDPTQQKIMMFLPLIFTALFLNFPSGLVLYWLVNNVLSIAQQQMMIRKFKANAAAK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=290, Percent_Identity=43.448275862069, Blast_Score=263, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24662345, Length=208, Percent_Identity=26.4423076923077, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356443, Length=208, Percent_Identity=26.4423076923077, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 60590; Mature: 60590

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDGKNLLIAIVLCLIVIVGWGYLAEYMGWATRPAPVAQQSQDQQAAHPQPQAQTQAAPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCC
QASLPVFTPAPGRDLTVDTPLYEAVVYSGGGALRSFKLKKYQVGLAADSPQVNMVDPKSA
CCCCCEECCCCCCCCEECCCHHHHHEECCCCHHHHEEEEEEEEEEECCCCCCEEECCCCC
QVAPLGLVINSQPSWSTGQWSMDTGENGLALEQGQQGTLRLVGEVDNLRVVREMTFSATN
CEEEEEEEEECCCCCCCCCEECCCCCCCCEECCCCCCCEEEEECHHHHHHHHHHHHHHHH
YLIREKIRVVNQTQQARSVRVSYTVAADASNAAGDRYDAMRVAWDNDGSLKEESSASTLE
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHH
STGVQAVGKIYWAGAMSTYFLAAVLPGDVNNVTVKGVMQQNVYRTAVEEQETLLGPGQEK
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
ELSVSYWVGPKVRSELQAVSPQLAKSVDLGFFHIIAKGLLWLLEFFHKYVHNWGLAIILL
CEEEEEECCHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TVLIKAAFWPLTAKSYASMEKMKKLQPHMMEIREKFKDNKEQMNKEVMALYKTYGVNPAS
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GCVPILIQLPVFFGLYQALLTSIELRHAPFITYLPGTDILWLADLSTKDPLYITPVIMGL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCEEEHHHHHHH
TMFLQQRMSPPATDPTQQKIMMFLPLIFTALFLNFPSGLVLYWLVNNVLSIAQQQMMIRK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FKANAAAK
HHHCCCCC
>Mature Secondary Structure
MQDGKNLLIAIVLCLIVIVGWGYLAEYMGWATRPAPVAQQSQDQQAAHPQPQAQTQAAPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCC
QASLPVFTPAPGRDLTVDTPLYEAVVYSGGGALRSFKLKKYQVGLAADSPQVNMVDPKSA
CCCCCEECCCCCCCCEECCCHHHHHEECCCCHHHHEEEEEEEEEEECCCCCCEEECCCCC
QVAPLGLVINSQPSWSTGQWSMDTGENGLALEQGQQGTLRLVGEVDNLRVVREMTFSATN
CEEEEEEEEECCCCCCCCCEECCCCCCCCEECCCCCCCEEEEECHHHHHHHHHHHHHHHH
YLIREKIRVVNQTQQARSVRVSYTVAADASNAAGDRYDAMRVAWDNDGSLKEESSASTLE
HHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHH
STGVQAVGKIYWAGAMSTYFLAAVLPGDVNNVTVKGVMQQNVYRTAVEEQETLLGPGQEK
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
ELSVSYWVGPKVRSELQAVSPQLAKSVDLGFFHIIAKGLLWLLEFFHKYVHNWGLAIILL
CEEEEEECCHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
TVLIKAAFWPLTAKSYASMEKMKKLQPHMMEIREKFKDNKEQMNKEVMALYKTYGVNPAS
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GCVPILIQLPVFFGLYQALLTSIELRHAPFITYLPGTDILWLADLSTKDPLYITPVIMGL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCEEEHHHHHHH
TMFLQQRMSPPATDPTQQKIMMFLPLIFTALFLNFPSGLVLYWLVNNVLSIAQQQMMIRK
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FKANAAAK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA