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The map label for this gene is 220905224

Identifier: 220905224

GI number: 220905224

Start: 2365214

End: 2366695

Strand: Reverse

Name: 220905224

Synonym: Ddes_1962

Alternate gene names: NA

Gene position: 2366695-2365214 (Counterclockwise)

Preceding gene: 220905225

Following gene: 220905223

Centisome position: 82.36

GC content: 62.69

Gene sequence:

>1482_bases
ATGAAGTCCGTGCACAAAAAATTTTGCGCGAACCGACATGGCGGCAAAGGGCATGACAGCAAGAGGCGGGATGACGTCTG
CCGGAGCCGCACAAACCGGCATGCCAGCGAAGCTGTTGCCGGTTGTGAGCTGACAGCGTGGTCCGCAATGGAAAGCCTGC
CTGCCGGGCAAACCGCGGCGGATGCTCCTGCCGCACTTTCTGCCTTGCCTCCTCCCATAGCCGCCGGTGCATCCCCGGAC
GCAGCCGGCGAAGATCCCATTGCCGCGGCCACGCAGGAATTTTGTGTGGACCATCAGCATGCAGGTTTGCGGCTTGATCA
GGCTCTGGAACATCTTTTGCCGCATATGGGCTTGCGTGGGCGCAGGCGCTGCGCTGAAAATGGTGGCGTATCGGTAAACG
GCCGCGCCGCAAAAGCTTCGCGCCGCATGCGCCAGGGGGATGTGGTGCGCCTGCACAATGCGGAAGCACGAAAAAAAAAG
GTGGCCTTGGGCCGCGAGGTTTCCGGCACGGCGTTTTCTTGCGGCTCTGCTGTTGCCGCCTGCGGGCTGCGTATGCTCGG
CAGGCAGGGAGAGTATTGTTTTTTCAGTAAGCCCGCGCGTATGCACAGCGCCTCTCTGGCGGGTATTTCCGGTGTGAGTG
TGGAGGCTCTGGCTCCGGCCCTTGCCGTGCGGTGGACTGAAAAAAGCGGCAGCGGCAATGAGTTCGATCTGGCAGCGCTC
ACTTTGATGCAACGTCTGGATTTCGGCACTTCAGGCCTTTTGTGCGCGGCGCTTTCGACCTCCGCCGCTGAAGATTTTCG
TGCCGCAGAAGCGGCCGGGCTGTGTGAAAAACGCTATGTGGCCCTGCTTTCGGGCGTGCTTTCCGGCCCTGTTGTGGCAC
GGCAGGAGCTGGACGTCAGCAAAAGGCGCAAGAGCCGTGTGCTGCCCGCACTCGCGCACCATACGCGCTGGACGGAGTTT
TGGCCCCTGCATGTCTGGAGGCCCGGCGACGTGTCTGTACAGGCCCTGCAGGCGTTGCTTGGGCCTGCAGGGGGCGGAGC
GCCTGAAAACGATGCCCCTGTTGTCACGCCGGAAGCAGGGGGGCTGCCGGTTCCCGCCGCCGGGCTCACGCTGGCGGCCT
GCCGCATACGCAGGGGGGCGCGCCATCAGATACGCGCGCATGCGGCTGGTCTGGGACATCCTCTGTGGGGGGACAGCCTG
TATGCGGAGCCGGAAGAACATGTGGCGGCCAGTGGCGGCCTTGCCGTAGCTCTGCCTTTGACGTTCTCCAGTGGCAATAC
CGAAGATGCCAATATGCCGAGTCTTCGTGTTTTTTCTCCTTTGTGTGATGGCGCAGGATTTTTTTTGCATCATGGCGGCC
TGCGCCTGCCCGGTGCGGCAGTGACAGACGATCTCCCCTGGCTTCTGCCCTCTGGCTGCATGAAGGCCGCAAGGGACTGG
CTGGCCGGAATTTTGACCGGCAGGGAGCCTTCGGGGACATAG

Upstream 100 bases:

>100_bases
TCGCCCCCTGGTGTATGAGAACGATCCGCAGCATCATGATCCGGTACTGACAGCGCGCGCGCTTTTTGAGCTTTTGCCCG
GCAATGCTGCGGAGATATGA

Downstream 100 bases:

>100_bases
GAGTTGAGTGTTTAAACAGTTTTTTTTCTATAAAAATAATACATCCAATATGTTGAAATTAAAGGTGATATATTTATAGA
AAATAAAAGTTTTATTTGTC

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA Pseudouridine Synthase Family Protein; Pseudouridylate Synthase

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MKSVHKKFCANRHGGKGHDSKRRDDVCRSRTNRHASEAVAGCELTAWSAMESLPAGQTAADAPAALSALPPPIAAGASPD
AAGEDPIAAATQEFCVDHQHAGLRLDQALEHLLPHMGLRGRRRCAENGGVSVNGRAAKASRRMRQGDVVRLHNAEARKKK
VALGREVSGTAFSCGSAVAACGLRMLGRQGEYCFFSKPARMHSASLAGISGVSVEALAPALAVRWTEKSGSGNEFDLAAL
TLMQRLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQELDVSKRRKSRVLPALAHHTRWTEF
WPLHVWRPGDVSVQALQALLGPAGGGAPENDAPVVTPEAGGLPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSL
YAEPEEHVAASGGLAVALPLTFSSGNTEDANMPSLRVFSPLCDGAGFFLHHGGLRLPGAAVTDDLPWLLPSGCMKAARDW
LAGILTGREPSGT

Sequences:

>Translated_493_residues
MKSVHKKFCANRHGGKGHDSKRRDDVCRSRTNRHASEAVAGCELTAWSAMESLPAGQTAADAPAALSALPPPIAAGASPD
AAGEDPIAAATQEFCVDHQHAGLRLDQALEHLLPHMGLRGRRRCAENGGVSVNGRAAKASRRMRQGDVVRLHNAEARKKK
VALGREVSGTAFSCGSAVAACGLRMLGRQGEYCFFSKPARMHSASLAGISGVSVEALAPALAVRWTEKSGSGNEFDLAAL
TLMQRLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQELDVSKRRKSRVLPALAHHTRWTEF
WPLHVWRPGDVSVQALQALLGPAGGGAPENDAPVVTPEAGGLPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSL
YAEPEEHVAASGGLAVALPLTFSSGNTEDANMPSLRVFSPLCDGAGFFLHHGGLRLPGAAVTDDLPWLLPSGCMKAARDW
LAGILTGREPSGT
>Mature_493_residues
MKSVHKKFCANRHGGKGHDSKRRDDVCRSRTNRHASEAVAGCELTAWSAMESLPAGQTAADAPAALSALPPPIAAGASPD
AAGEDPIAAATQEFCVDHQHAGLRLDQALEHLLPHMGLRGRRRCAENGGVSVNGRAAKASRRMRQGDVVRLHNAEARKKK
VALGREVSGTAFSCGSAVAACGLRMLGRQGEYCFFSKPARMHSASLAGISGVSVEALAPALAVRWTEKSGSGNEFDLAAL
TLMQRLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQELDVSKRRKSRVLPALAHHTRWTEF
WPLHVWRPGDVSVQALQALLGPAGGGAPENDAPVVTPEAGGLPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSL
YAEPEEHVAASGGLAVALPLTFSSGNTEDANMPSLRVFSPLCDGAGFFLHHGGLRLPGAAVTDDLPWLLPSGCMKAARDW
LAGILTGREPSGT

Specific function: Unknown

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51605; Mature: 51605

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVHKKFCANRHGGKGHDSKRRDDVCRSRTNRHASEAVAGCELTAWSAMESLPAGQTAA
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
DAPAALSALPPPIAAGASPDAAGEDPIAAATQEFCVDHQHAGLRLDQALEHLLPHMGLRG
CCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCH
RRRCAENGGVSVNGRAAKASRRMRQGDVVRLHNAEARKKKVALGREVSGTAFSCGSAVAA
HHHHHCCCCEEECCHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHH
CGLRMLGRQGEYCFFSKPARMHSASLAGISGVSVEALAPALAVRWTEKSGSGNEFDLAAL
HHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHCCHHEEEECCCCCCCCHHHHHH
TLMQRLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQELDVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
KRRKSRVLPALAHHTRWTEFWPLHVWRPGDVSVQALQALLGPAGGGAPENDAPVVTPEAG
HHHHHHHHHHHHHCCCCCEECEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCC
GLPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSLYAEPEEHVAASGGLAVALPL
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEE
TFSSGNTEDANMPSLRVFSPLCDGAGFFLHHGGLRLPGAAVTDDLPWLLPSGCMKAARDW
EECCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LAGILTGREPSGT
HHHHHCCCCCCCC
>Mature Secondary Structure
MKSVHKKFCANRHGGKGHDSKRRDDVCRSRTNRHASEAVAGCELTAWSAMESLPAGQTAA
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
DAPAALSALPPPIAAGASPDAAGEDPIAAATQEFCVDHQHAGLRLDQALEHLLPHMGLRG
CCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCH
RRRCAENGGVSVNGRAAKASRRMRQGDVVRLHNAEARKKKVALGREVSGTAFSCGSAVAA
HHHHHCCCCEEECCHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHH
CGLRMLGRQGEYCFFSKPARMHSASLAGISGVSVEALAPALAVRWTEKSGSGNEFDLAAL
HHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHCCHHEEEECCCCCCCCHHHHHH
TLMQRLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQELDVS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHH
KRRKSRVLPALAHHTRWTEFWPLHVWRPGDVSVQALQALLGPAGGGAPENDAPVVTPEAG
HHHHHHHHHHHHHCCCCCEECEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCC
GLPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSLYAEPEEHVAASGGLAVALPL
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEE
TFSSGNTEDANMPSLRVFSPLCDGAGFFLHHGGLRLPGAAVTDDLPWLLPSGCMKAARDW
EECCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LAGILTGREPSGT
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA