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The map label for this gene is hypB [H]

Identifier: 220904765

GI number: 220904765

Start: 1788933

End: 1789601

Strand: Reverse

Name: hypB [H]

Synonym: Ddes_1497

Alternate gene names: 220904765

Gene position: 1789601-1788933 (Counterclockwise)

Preceding gene: 220904766

Following gene: 220904763

Centisome position: 62.28

GC content: 56.05

Gene sequence:

>669_bases
ATGCAAATTCCCGTGGTTCGCAATGTGCTGGAAGCCAATGAAAAAATGGCGGCTCATGTGCGCAAGCGGCTGTCTGACAG
CGGGATTCTGACCCTGAATCTCATCAGTTCGCCCGGCGCGGGCAAGACCACGCTGCTGGAGCGCACGCTTACCGATCTGG
CGGGAGAGTTTCGCATGGCCGTGGTGGAAGGCGACCTGCAGACAGACAATGATGCGCGCCGCGTGGCCGCTACCGGGGCA
CAGGCCGTGCAGATCAATACCGATGGCGGCTGCCACCTTGACAGCAATATGATTCTGACAGCGCTGGATAGTCTTGATCT
TGAAGGCGTGGATATTCTTTTTATCGAAAATGTGGGCAATCTTGTCTGCCCTGTGGAATTTGACTGTGGTGAAGATGCCA
AGGTTGCCCTGCTGAGCGTTGCCGAAGGCGACGACAAGCCCGAGAAGTACCCGCTTCTTTTCAATCTGGCCCAGGCGCTC
GTGCTGAACAAGGTAGACCTGCTGCCCTATGTGGACTTTGATATGGGGCGGGCCCGTAATTTTGCCACCAAGCTCAACAA
GAAGCTGGATATTTTTGAAGTTTCCTGCCGCCATGGGCAGGGTCTTCAGGAGTGGTACGACTGGTTGCGCGCCATGCGGG
CTGCCAAAAAAGAAGGCCGTCCGCTTTAA

Upstream 100 bases:

>100_bases
TGGCACTTTTTTAACGATCTATATCATTCATCATCGCCTTCTCAACGTACCGATACTTCACATAAAAGACCCCATTGCCG
GGGCCTGCAAGGAGACTGGC

Downstream 100 bases:

>100_bases
AGGCCTCTGTACAGCGTTGACAGAACTTGCATGCCCGTCCCGGGAAAGTGCCGCACGGCTCTGTGCTGCATTTTTCCGGG
ACGGTTTTTTGCGGCACACA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MQIPVVRNVLEANEKMAAHVRKRLSDSGILTLNLISSPGAGKTTLLERTLTDLAGEFRMAVVEGDLQTDNDARRVAATGA
QAVQINTDGGCHLDSNMILTALDSLDLEGVDILFIENVGNLVCPVEFDCGEDAKVALLSVAEGDDKPEKYPLLFNLAQAL
VLNKVDLLPYVDFDMGRARNFATKLNKKLDIFEVSCRHGQGLQEWYDWLRAMRAAKKEGRPL

Sequences:

>Translated_222_residues
MQIPVVRNVLEANEKMAAHVRKRLSDSGILTLNLISSPGAGKTTLLERTLTDLAGEFRMAVVEGDLQTDNDARRVAATGA
QAVQINTDGGCHLDSNMILTALDSLDLEGVDILFIENVGNLVCPVEFDCGEDAKVALLSVAEGDDKPEKYPLLFNLAQAL
VLNKVDLLPYVDFDMGRARNFATKLNKKLDIFEVSCRHGQGLQEWYDWLRAMRAAKKEGRPL
>Mature_222_residues
MQIPVVRNVLEANEKMAAHVRKRLSDSGILTLNLISSPGAGKTTLLERTLTDLAGEFRMAVVEGDLQTDNDARRVAATGA
QAVQINTDGGCHLDSNMILTALDSLDLEGVDILFIENVGNLVCPVEFDCGEDAKVALLSVAEGDDKPEKYPLLFNLAQAL
VLNKVDLLPYVDFDMGRARNFATKLNKKLDIFEVSCRHGQGLQEWYDWLRAMRAAKKEGRPL

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=208, Percent_Identity=50.9615384615385, Blast_Score=212, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24412; Mature: 24412

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPVVRNVLEANEKMAAHVRKRLSDSGILTLNLISSPGAGKTTLLERTLTDLAGEFRMA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEE
VVEGDLQTDNDARRVAATGAQAVQINTDGGCHLDSNMILTALDSLDLEGVDILFIENVGN
EEECCCCCCCCHHHHHHCCCEEEEEECCCCCEECCCHHEEECCCCCCCCEEEEEEECCCC
LVCPVEFDCGEDAKVALLSVAEGDDKPEKYPLLFNLAQALVLNKVDLLPYVDFDMGRARN
EEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHH
FATKLNKKLDIFEVSCRHGQGLQEWYDWLRAMRAAKKEGRPL
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQIPVVRNVLEANEKMAAHVRKRLSDSGILTLNLISSPGAGKTTLLERTLTDLAGEFRMA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEE
VVEGDLQTDNDARRVAATGAQAVQINTDGGCHLDSNMILTALDSLDLEGVDILFIENVGN
EEECCCCCCCCHHHHHHCCCEEEEEECCCCCEECCCHHEEECCCCCCCCEEEEEEECCCC
LVCPVEFDCGEDAKVALLSVAEGDDKPEKYPLLFNLAQALVLNKVDLLPYVDFDMGRARN
EEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHH
FATKLNKKLDIFEVSCRHGQGLQEWYDWLRAMRAAKKEGRPL
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]