Click here to switch to the map view.

The map label for this gene is cheB [H]

Identifier: 220904645

GI number: 220904645

Start: 1649052

End: 1650122

Strand: Direct

Name: cheB [H]

Synonym: Ddes_1377

Alternate gene names: 220904645

Gene position: 1649052-1650122 (Clockwise)

Preceding gene: 220904644

Following gene: 220904646

Centisome position: 57.39

GC content: 58.36

Gene sequence:

>1071_bases
ATGATCCGTGTTCTTGTAGTCGACGATTCCACTTTTATGCGAAATGCCATTACCGCCCTGCTGGAACAGGATCCGGAAAT
CAAGGTTGCCGGTACTGCCAAAGATGGATTGGAAGCCCTGAAAAAAGCCGAAGAACTAGATGCGGACGTCATGACCCTGG
ATGTGGAAATGCCGCGTCTTGACGGCCTGGGGACCCTCCAGCGGCTTATGAAGGCCACCCCCATGCCGGTACTCATGATC
AGCTCTCTGACCGAAAGTGGCGCAGAAAGCACCTTAAAAGCTATGGAGTACGGCGCACTGGACTTTATTCCCAAAAATAT
GAGCAATGATCGTGATGCCTTCGGCGCGGAACTGCGGCGCAAGGTCACGGCTCTGGCACGCCGCAAAACGATTATCCGTC
TCAAGTACCGCCGTATCAACAATATCCCCATGCCGGCCGCCACGCCGCGCACACAGCCGCAGCAGCCCGCCGATTATGTG
CAGACTCCCTGCCCCGGGCCGCGCGATCTGGTAGTTATCGGCGTGTCCACCGGGGGGCCGCCGGTGGTGCAAAAAATACT
TTCTGCCCTGCCTCCGGACATTCCGGCCTGCTTCCTGATTGCACAGCATATGCCCGCAGCCTTTACCGGCCCTTTTGCCA
AAAGGCTCGACAGCGTATGCCGCATAGACGTCACTGAAGCGCAGGACGGCGATCGTTTGAAGAACGGACACGCCTACGTC
TGTCCCGGCGGCAGGCACATAAGCGTCCGCATGCGCGGTCCCCTGCCCGAAGTGGCTGTGACCGAAGAGCCGCGCGACGC
CCTTTACAAGCCCACGGTCAACCTGCTTATGGAAAGTGCGGGCAAGCTTATGGGGCGCCGCACCCTGGGCGTCATGCTCA
CGGGCATGGGTTCGGACGGATGTGAGGGCGCAAGGGTTTTGAGAGAAAAAGGCGGCTGCCTCATTGCCCAGAATGAAGCC
TCTTGTGTAGTGTACGGCATGCCCAAGGCAGTAGTGGACGCCAAGCTTGCAAACCAGATTCTCGACGCCGACGACATAGC
CCAGGCCATCATGACGATAATCAGAGGCTGA

Upstream 100 bases:

>100_bases
AATTTTTGCAAGCCATTTTTTATTTGTAAAAAAATAAGGCCTGACGTAGCATGACGTTGTCCCTTGGAGGCATAAAATCT
TTGCGGAGCGAGCAGCCTGT

Downstream 100 bases:

>100_bases
CCAGCAGCGCAGCAGGAAACGACACTATGGAACATACGCTCAATACGTCTTCGCCCATTCTGGAAGCATTGCAGTCCAAC
GACAGCACGACTATCCGCAA

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIRVLVVDDSTFMRNAITALLEQDPEIKVAGTAKDGLEALKKAEELDADVMTLDVEMPRLDGLGTLQRLMKATPMPVLMI
SSLTESGAESTLKAMEYGALDFIPKNMSNDRDAFGAELRRKVTALARRKTIIRLKYRRINNIPMPAATPRTQPQQPADYV
QTPCPGPRDLVVIGVSTGGPPVVQKILSALPPDIPACFLIAQHMPAAFTGPFAKRLDSVCRIDVTEAQDGDRLKNGHAYV
CPGGRHISVRMRGPLPEVAVTEEPRDALYKPTVNLLMESAGKLMGRRTLGVMLTGMGSDGCEGARVLREKGGCLIAQNEA
SCVVYGMPKAVVDAKLANQILDADDIAQAIMTIIRG

Sequences:

>Translated_356_residues
MIRVLVVDDSTFMRNAITALLEQDPEIKVAGTAKDGLEALKKAEELDADVMTLDVEMPRLDGLGTLQRLMKATPMPVLMI
SSLTESGAESTLKAMEYGALDFIPKNMSNDRDAFGAELRRKVTALARRKTIIRLKYRRINNIPMPAATPRTQPQQPADYV
QTPCPGPRDLVVIGVSTGGPPVVQKILSALPPDIPACFLIAQHMPAAFTGPFAKRLDSVCRIDVTEAQDGDRLKNGHAYV
CPGGRHISVRMRGPLPEVAVTEEPRDALYKPTVNLLMESAGKLMGRRTLGVMLTGMGSDGCEGARVLREKGGCLIAQNEA
SCVVYGMPKAVVDAKLANQILDADDIAQAIMTIIRG
>Mature_356_residues
MIRVLVVDDSTFMRNAITALLEQDPEIKVAGTAKDGLEALKKAEELDADVMTLDVEMPRLDGLGTLQRLMKATPMPVLMI
SSLTESGAESTLKAMEYGALDFIPKNMSNDRDAFGAELRRKVTALARRKTIIRLKYRRINNIPMPAATPRTQPQQPADYV
QTPCPGPRDLVVIGVSTGGPPVVQKILSALPPDIPACFLIAQHMPAAFTGPFAKRLDSVCRIDVTEAQDGDRLKNGHAYV
CPGGRHISVRMRGPLPEVAVTEEPRDALYKPTVNLLMESAGKLMGRRTLGVMLTGMGSDGCEGARVLREKGGCLIAQNEA
SCVVYGMPKAVVDAKLANQILDADDIAQAIMTIIRG

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=353, Percent_Identity=38.8101983002833, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38487; Mature: 38487

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00120 LIPASE_SER ; PS50122 CHEB ; PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLVVDDSTFMRNAITALLEQDPEIKVAGTAKDGLEALKKAEELDADVMTLDVEMPRL
CEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCC
DGLGTLQRLMKATPMPVLMISSLTESGAESTLKAMEYGALDFIPKNMSNDRDAFGAELRR
CCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHH
KVTALARRKTIIRLKYRRINNIPMPAATPRTQPQQPADYVQTPCPGPRDLVVIGVSTGGP
HHHHHHHHHHHEEEEEHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCH
PVVQKILSALPPDIPACFLIAQHMPAAFTGPFAKRLDSVCRIDVTEAQDGDRLKNGHAYV
HHHHHHHHHCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHEEEECCCCCCCCCCCCCEEE
CPGGRHISVRMRGPLPEVAVTEEPRDALYKPTVNLLMESAGKLMGRRTLGVMLTGMGSDG
CCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
CEGARVLREKGGCLIAQNEASCVVYGMPKAVVDAKLANQILDADDIAQAIMTIIRG
CHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRVLVVDDSTFMRNAITALLEQDPEIKVAGTAKDGLEALKKAEELDADVMTLDVEMPRL
CEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCC
DGLGTLQRLMKATPMPVLMISSLTESGAESTLKAMEYGALDFIPKNMSNDRDAFGAELRR
CCHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHH
KVTALARRKTIIRLKYRRINNIPMPAATPRTQPQQPADYVQTPCPGPRDLVVIGVSTGGP
HHHHHHHHHHHEEEEEHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCH
PVVQKILSALPPDIPACFLIAQHMPAAFTGPFAKRLDSVCRIDVTEAQDGDRLKNGHAYV
HHHHHHHHHCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHEEEECCCCCCCCCCCCCEEE
CPGGRHISVRMRGPLPEVAVTEEPRDALYKPTVNLLMESAGKLMGRRTLGVMLTGMGSDG
CCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
CEGARVLREKGGCLIAQNEASCVVYGMPKAVVDAKLANQILDADDIAQAIMTIIRG
CHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA