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The map label for this gene is acpS

Identifier: 220904414

GI number: 220904414

Start: 1346358

End: 1346732

Strand: Reverse

Name: acpS

Synonym: Ddes_1144

Alternate gene names: 220904414

Gene position: 1346732-1346358 (Counterclockwise)

Preceding gene: 220904422

Following gene: 220904413

Centisome position: 46.87

GC content: 57.6

Gene sequence:

>375_bases
ATGATTGTCGGCTTGGGTGTTGATATTGTTGAGCTTGCGCGCATAGAAAAAAGCCTCACACGCTTCGGACGCCGCTTTGC
CGAAAAAGTTCTCAGCCCCGAAGAGATGGCCGCAATGCCCACTCTGACCGTCAATTACATAGCCGGGCGTTTTGCGGTCA
AGGAGGCCGCCGTGAAAGCATTGGGAACGGGTTTCAGCCAGGGGATCGGTCCCACTCTTGTGGAAACAGTAGCAACTTCC
GGCGGCAAACCGCAACTGCGCCTGCATGGGGCCGCCCTGCAATGCGCCCGGGATCTGGGCGTGACCTCTTGCCATGTATC
GATCAGCCATGACCGCTCATCTGCCGTGGCCGTGGTAGTTCTGGAGGCGTTATAA

Upstream 100 bases:

>100_bases
CCGAATGGCCGCATATACGACATTTTTTTTCATTGGGCAACCAGCCCTTTAGGGGGTATTCCCCTGAAATATACTTTTTT
TCACAACGGAGCGATGACGC

Downstream 100 bases:

>100_bases
TGCCCGCTCCTGCCTGCCCCCCACCCTTTTTCCCTCCCCTGCCCCTGCCTGAAGAAATGCGTGCCTGGGACAAGGGCGCG
GCAGACCTCGGCCTGCCCGA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MIVGLGVDIVELARIEKSLTRFGRRFAEKVLSPEEMAAMPTLTVNYIAGRFAVKEAAVKALGTGFSQGIGPTLVETVATS
GGKPQLRLHGAALQCARDLGVTSCHVSISHDRSSAVAVVVLEAL

Sequences:

>Translated_124_residues
MIVGLGVDIVELARIEKSLTRFGRRFAEKVLSPEEMAAMPTLTVNYIAGRFAVKEAAVKALGTGFSQGIGPTLVETVATS
GGKPQLRLHGAALQCARDLGVTSCHVSISHDRSSAVAVVVLEAL
>Mature_124_residues
MIVGLGVDIVELARIEKSLTRFGRRFAEKVLSPEEMAAMPTLTVNYIAGRFAVKEAAVKALGTGFSQGIGPTLVETVATS
GGKPQLRLHGAALQCARDLGVTSCHVSISHDRSSAVAVVVLEAL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=47.5806451612903, Blast_Score=107, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325025, Length=122, Percent_Identity=39.344262295082, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_DESDA (B8IZX1)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479726.1
- GeneID:   7284826
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1144
- HOGENOM:   HBG734479
- ProtClustDB:   PRK14657
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 12988; Mature: 12988

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLGVDIVELARIEKSLTRFGRRFAEKVLSPEEMAAMPTLTVNYIAGRFAVKEAAVKA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LGTGFSQGIGPTLVETVATSGGKPQLRLHGAALQCARDLGVTSCHVSISHDRSSAVAVVV
HHCCCCCCCCHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEEEECCCCCCEEEEEE
LEAL
EECC
>Mature Secondary Structure
MIVGLGVDIVELARIEKSLTRFGRRFAEKVLSPEEMAAMPTLTVNYIAGRFAVKEAAVKA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LGTGFSQGIGPTLVETVATSGGKPQLRLHGAALQCARDLGVTSCHVSISHDRSSAVAVVV
HHCCCCCCCCHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEEEECCCCCCEEEEEE
LEAL
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA