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The map label for this gene is fecD [C]

Identifier: 220904263

GI number: 220904263

Start: 1157491

End: 1158627

Strand: Reverse

Name: fecD [C]

Synonym: Ddes_0990

Alternate gene names: 220904263

Gene position: 1158627-1157491 (Counterclockwise)

Preceding gene: 220904264

Following gene: 220904262

Centisome position: 40.32

GC content: 60.69

Gene sequence:

>1137_bases
ATGCCCGGTAAGAAACCTTGCGGCGACGAAAACAACACCGCACAGTCTCACGCTTATTGTGGCAGCCCAGACGGACGCCT
CAGCAACAGCACAGAAAAACGTCACTGCTGCTCCCTGCCGTGGGACAGCCCTTTCATGCGGGCCTGCACAGCAACGGCAC
TGCTGGCCGCTGCCGTACTGCTGGGGCTGACGGGCATGAAGCTTGGGGCAGTCTCACGCTCCTGGGCCGACATATGTTCG
GCCCTGTTCAGTCCTTCAGGCGATGAATCCTTACGCTATTTTGTGCTCCACCTGCGGCTGCCCAAAGTTTGCGCCGCCCT
GACTGTGGGTGCATCGCTGGCTCTTGCCGGAACCATGTTGCAAAACGTGCTCAACAATCCGCTGGCTTCGTCCTTTACCC
TCGGCCTTTCACAGGGAGCCGCCTTCGGAGCCAGTTTTTCCATGATCATCCTGCCCGCCGCAGGCGGCCTGGCCGGCCTG
AGCATTGTAGCCATGGGCGCACTGGCCGGCTCCCTCGGCGCGTCTCTGCTTATACTGGCCTTCAGTATGGTGCGCGGCAT
GGGGCCGCAGGGGCTTATACTTGCGGGGGTGGCATTGTCGACCCTTTTCGGGGCCGCCACCATGTCGTTACAGTATTTCG
CCACTGACAGCCAGGTGGCGGCTACCGTATTCTGGAGCTTTGGCGACCTGAGCAGAGGAAGCTGGCGCGAGGTCGCGCTG
GTAGGGCTTGTGCTGCTGGCAGGTCTTGCCTTTTCCCTGCGTCACAACCTTGACTACGACACGCTGCGCTGGGGCGATGC
CCAGGCCACGGCCCTGGGTGTACCTGTTCTGCGCCTGCGCTGTGCAACCCTGTTCATGGCCTCGCTTATGGCCGCCTTTG
CCACCGCCTTTTACGGCGTCATCGGCTTTGTGGGCCTGGTGGCTCCTCACATGGTGCGCCTGACATTTCCCCATGCCGGA
CATTTTTTTCTGCTGGGCTGCTCTGCCCTGTTCGGCGCATGCTTTTTACTGGCGGCCGACCTTGTAGCCCAGACCATCAT
ATACCCTGCCCTGCTGCCCATAGGCATTGTCTGCGCTTTCACCGGAGTGCCCGTTTTTTTATGCATCCTTTTCAGGGGGG
CCAAAGCACATGCTTGA

Upstream 100 bases:

>100_bases
GAAATATTCATCCTTTTCAACGGTTACCCTCTTTATGAAGACATGGTGCGCGTCACCGGCAGGCCGGGCAGGCTGCAGTT
GACGGGGCAGGGGCTGGACT

Downstream 100 bases:

>100_bases
GGCCAAAAACCTTTCTCTTGTGGCGCGATCCGGCAGAACTATCCTTGACGGCGTATCCTTCCGTCTTGAGCCAGGACGCT
GCATGGCCCTCATCGGCCCC

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPGKKPCGDENNTAQSHAYCGSPDGRLSNSTEKRHCCSLPWDSPFMRACTATALLAAAVLLGLTGMKLGAVSRSWADICS
ALFSPSGDESLRYFVLHLRLPKVCAALTVGASLALAGTMLQNVLNNPLASSFTLGLSQGAAFGASFSMIILPAAGGLAGL
SIVAMGALAGSLGASLLILAFSMVRGMGPQGLILAGVALSTLFGAATMSLQYFATDSQVAATVFWSFGDLSRGSWREVAL
VGLVLLAGLAFSLRHNLDYDTLRWGDAQATALGVPVLRLRCATLFMASLMAAFATAFYGVIGFVGLVAPHMVRLTFPHAG
HFFLLGCSALFGACFLLAADLVAQTIIYPALLPIGIVCAFTGVPVFLCILFRGAKAHA

Sequences:

>Translated_378_residues
MPGKKPCGDENNTAQSHAYCGSPDGRLSNSTEKRHCCSLPWDSPFMRACTATALLAAAVLLGLTGMKLGAVSRSWADICS
ALFSPSGDESLRYFVLHLRLPKVCAALTVGASLALAGTMLQNVLNNPLASSFTLGLSQGAAFGASFSMIILPAAGGLAGL
SIVAMGALAGSLGASLLILAFSMVRGMGPQGLILAGVALSTLFGAATMSLQYFATDSQVAATVFWSFGDLSRGSWREVAL
VGLVLLAGLAFSLRHNLDYDTLRWGDAQATALGVPVLRLRCATLFMASLMAAFATAFYGVIGFVGLVAPHMVRLTFPHAG
HFFLLGCSALFGACFLLAADLVAQTIIYPALLPIGIVCAFTGVPVFLCILFRGAKAHA
>Mature_377_residues
PGKKPCGDENNTAQSHAYCGSPDGRLSNSTEKRHCCSLPWDSPFMRACTATALLAAAVLLGLTGMKLGAVSRSWADICSA
LFSPSGDESLRYFVLHLRLPKVCAALTVGASLALAGTMLQNVLNNPLASSFTLGLSQGAAFGASFSMIILPAAGGLAGLS
IVAMGALAGSLGASLLILAFSMVRGMGPQGLILAGVALSTLFGAATMSLQYFATDSQVAATVFWSFGDLSRGSWREVALV
GLVLLAGLAFSLRHNLDYDTLRWGDAQATALGVPVLRLRCATLFMASLMAAFATAFYGVIGFVGLVAPHMVRLTFPHAGH
FFLLGCSALFGACFLLAADLVAQTIIYPALLPIGIVCAFTGVPVFLCILFRGAKAHA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=310, Percent_Identity=33.8709677419355, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788004, Length=295, Percent_Identity=33.8983050847458, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786347, Length=366, Percent_Identity=30.6010928961749, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790741, Length=307, Percent_Identity=31.2703583061889, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=31.2121212121212, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786805, Length=292, Percent_Identity=34.5890410958904, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39208; Mature: 39076

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKKPCGDENNTAQSHAYCGSPDGRLSNSTEKRHCCSLPWDSPFMRACTATALLAAAVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LGLTGMKLGAVSRSWADICSALFSPSGDESLRYFVLHLRLPKVCAALTVGASLALAGTML
HHHCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVLNNPLASSFTLGLSQGAAFGASFSMIILPAAGGLAGLSIVAMGALAGSLGASLLILA
HHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSMVRGMGPQGLILAGVALSTLFGAATMSLQYFATDSQVAATVFWSFGDLSRGSWREVAL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHEEHHCCCCCCCHHHHHH
VGLVLLAGLAFSLRHNLDYDTLRWGDAQATALGVPVLRLRCATLFMASLMAAFATAFYGV
HHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFVGLVAPHMVRLTFPHAGHFFLLGCSALFGACFLLAADLVAQTIIYPALLPIGIVCAF
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGVPVFLCILFRGAKAHA
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PGKKPCGDENNTAQSHAYCGSPDGRLSNSTEKRHCCSLPWDSPFMRACTATALLAAAVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LGLTGMKLGAVSRSWADICSALFSPSGDESLRYFVLHLRLPKVCAALTVGASLALAGTML
HHHCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNVLNNPLASSFTLGLSQGAAFGASFSMIILPAAGGLAGLSIVAMGALAGSLGASLLILA
HHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FSMVRGMGPQGLILAGVALSTLFGAATMSLQYFATDSQVAATVFWSFGDLSRGSWREVAL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHEEHHCCCCCCCHHHHHH
VGLVLLAGLAFSLRHNLDYDTLRWGDAQATALGVPVLRLRCATLFMASLMAAFATAFYGV
HHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFVGLVAPHMVRLTFPHAGHFFLLGCSALFGACFLLAADLVAQTIIYPALLPIGIVCAF
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGVPVFLCILFRGAKAHA
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]