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The map label for this gene is mreA [H]

Identifier: 21910422

GI number: 21910422

Start: 942949

End: 943881

Strand: Reverse

Name: mreA [H]

Synonym: SpyM3_0886

Alternate gene names: 21910422

Gene position: 943881-942949 (Counterclockwise)

Preceding gene: 161485742

Following gene: 21910421

Centisome position: 49.66

GC content: 34.08

Gene sequence:

>933_bases
ATGGAAATTGAATATATCAAAAATTATCGTGATATTAACCAAGAAGATGATACAGTCTTGGTATTGGGATATTTTGATGG
ATTACACCGTGGCCATAAAGCCTTATTTGACAAAGCAAGAGAGGTTGCAAATAAAGAAGGGTTAAAAGTAGTCGTTTTTA
CGTTTACAGAGTCTCCGAAATTGGCTTTTTCGCGTTTTTCTCCTGAGTTATTGCTTCATATTACTTATCCAAAGAAGCGT
TATGAAAAATTTGCCGATTACGGTGTAAATAAATTATATTTGGTTGATTTTACTTCTAAATTCTCTAAGGTCTCATCTGA
TCATTTTATAACTCATTATATTAAAAACCTGAAAGCAAAGCATATTGTTGTCGGTTTTGACTATAAGTTTGGGCATAATT
GTACAGATAGTGATTATTTAGCCAGAAATTTTGAAGGACAAGTTTATACCATTGAGGAAATAAAAGAAGATCATCGAAAA
ATTTCTGCTACATGGATAAGGAAGCTTATTCAAGAAGGTAATGTAGTTAAAGCAAACCACTTGTTAGGCTATGACTTATC
GACAAGGGGAAGAGTCGTTCACGGGGATGCGCGTGGCCGTACTATTGGTTTCCCAACAGCCAATCTAACTCCAATTGACA
ACACATACTTACCAGCTGATGGAGTCTATGTTACAAATGTTATTGTTGCTAATAAAATCTATCGCTCTATGACGAGTTTA
GGTAAAAATGTGACATTTGGGGGGAAAGAGTTGCGTCTAGAAGTTAACATTTTTGACTTTGACGAAGAGATCTATGGAGA
AATTATTGAGATTGTTTGGTTAGATAAGATTCGAGACATGGAAAAATTCGAGGGAATCGAAGATTTGACTGATAGATTGG
AATATGATAAACGAACAGCATTAAATTGGAAAAAAGATAGCAAATTATCTTAA

Upstream 100 bases:

>100_bases
CATGGCGAAAAAGTAATTGCTATTTTAGAAAAAAGAGATCAAGAATACAAACCCAAAAAAGTTCTTATTTAAATAGTTTG
AGTAAGTAGAATGGATAATT

Downstream 100 bases:

>100_bases
ATTTTTGTATAATAAGGTAAGTAAATTTGATAGAGGAAAAATATGGTTACCTTATTTTTATCACCTAGCTGTACCAGTTG
TCGTAAAGCAAGGGCATGGT

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MEIEYIKNYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLARNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLTPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS

Sequences:

>Translated_310_residues
MEIEYIKNYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLARNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLTPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS
>Mature_310_residues
MEIEYIKNYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKR
YEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLARNFEGQVYTIEEIKEDHRK
ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLTPIDNTYLPADGVYVTNVIVANKIYRSMTSL
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=307, Percent_Identity=32.2475570032573, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 35979; Mature: 35979

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIEYIKNYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPK
CCCHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
LAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAK
HHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHCCCCHHHHHHHHCCCCC
HIVVGFDYKFGHNCTDSDYLARNFEGQVYTIEEIKEDHRKISATWIRKLIQEGNVVKANH
EEEEEEEECCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECE
LLGYDLSTRGRVVHGDARGRTIGFPTANLTPIDNTYLPADGVYVTNVIVANKIYRSMTSL
EEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
LNWKKDSKLS
CCCCCCCCCC
>Mature Secondary Structure
MEIEYIKNYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVANKEGLKVVVFTFTESPK
CCCHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
LAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFSKVSSDHFITHYIKNLKAK
HHHHHCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHCCCCHHHHHHHHCCCCC
HIVVGFDYKFGHNCTDSDYLARNFEGQVYTIEEIKEDHRKISATWIRKLIQEGNVVKANH
EEEEEEEECCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECE
LLGYDLSTRGRVVHGDARGRTIGFPTANLTPIDNTYLPADGVYVTNVIVANKIYRSMTSL
EEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
GKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDKIRDMEKFEGIEDLTDRLEYDKRTA
CCCEEECCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHC
LNWKKDSKLS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9454067; 9108293; 9384377 [H]