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The map label for this gene is coaA [H]

Identifier: 21910407

GI number: 21910407

Start: 928579

End: 929499

Strand: Direct

Name: coaA [H]

Synonym: SpyM3_0871

Alternate gene names: 21910407

Gene position: 928579-929499 (Clockwise)

Preceding gene: 21910400

Following gene: 161485743

Centisome position: 48.86

GC content: 31.6

Gene sequence:

>921_bases
ATGTCAAATAAATTTATCAACTTTGAAAAAATTTCTAGAGAGTCTTGGAAAACATTACATCAAAAAGCAAAAGCTCTCCT
CACACAAGAGGAACTTAAAAGTATTACTAGCTTAAATGATAACATCAGTATTAACGATGTCATTGATATCTACCTTCCAT
TAATTAATCTGATCCAGGTTTACAAAATTGCGCAAGAAAATCTTTCTTTTTCTAAAAGCCTTTTTCTAAAAAAAGACATT
CAATTAAGGCCTTTTATTATTGGAATTTCTGGTTCAGTAGCTGTTGGTAAATCAACAACTAGTCGTCTTTTACAACTTTT
ATTATCACGAACGCACCCCAATAGTCAAGTCGAACTGGTAACGACTGATGGTTTTTTATATCCTAATCAGTTTCTTATTG
AACAAGGACTGTTAAATCGTAAAGGATTTCCAGAATCTTATAACATGGAACTTCTCTTAGATTTTCTAGATTCCATCAAA
AATGGTCAAACGGCTTTTGCACCCGTCTATTCTCATGATATTTACGATATTATCCCAAATCAAAAACAATCATTTAATAA
CCCTGACTTCCTTATCGTCGAAGGTATTAATGTTTTTCAAAATCAACAAAACAATCGTTTATATATGAGTGATTACTTTG
ATTTTTCTATTTATATTGATGCAGACAGCAGTCACATCGAAACTTGGTACATTGAACGGTTTCTAAGCATTTTAAAATTA
GCAAAACGTGACCCTCATAATTATTATGCCCAATATGCACAATTACCTCGATCTGAGGCTATAGCATTTGCGCGCAACGT
TTGGAAAACCGTTAATTTAGAAAATCTTGAAAAATTCATTGAACCTACACGTAATCGTGCTGAATTAATTTTACATAAAA
GTGCTGATCATAAAATTGATGAAATTTACCTCAAAAAGTGA

Upstream 100 bases:

>100_bases
AGTTAATTGTATTAATTTTCGTGTAAATACTAACGAAAAATTATTTATTTTTTAACTAAAATGGTATAATGTAAGCACTG
TCAAATGATTAGGAGCTACC

Downstream 100 bases:

>100_bases
TAAAGGGTTGCCAAACGCATATATTTTCTATATAATAATGTAGTTAGATTAATTTGGAGGTGAAAACATTGGCAAATATT
AAATCAGCTATTAAACGCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSNKFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDI
QLRPFIIGISGSVAVGKSTTSRLLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKL
AKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKIDEIYLKK

Sequences:

>Translated_306_residues
MSNKFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDI
QLRPFIIGISGSVAVGKSTTSRLLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKL
AKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKIDEIYLKK
>Mature_305_residues
SNKFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQ
LRPFIIGISGSVAVGKSTTSRLLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIKN
GQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKLA
KRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKIDEIYLKK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=302, Percent_Identity=45.6953642384106, Blast_Score=264, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35609; Mature: 35478

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDIYLPLINLIQV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSRLLQLLLSRTHPNSQVELV
HHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCEEECCHHHHHHHHHHHHCCCCCCEEEEE
TTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIKNGQTAFAPVYSHDIYDIIPN
EECCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHCCHHHCCCC
QKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKL
CCCCCCCCCEEEEECCHHHCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHH
AKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKID
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCH
EIYLKK
HEEECC
>Mature Secondary Structure 
SNKFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISINDVIDIYLPLINLIQV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
YKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSRLLQLLLSRTHPNSQVELV
HHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCEEECCHHHHHHHHHHHHCCCCCCEEEEE
TTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIKNGQTAFAPVYSHDIYDIIPN
EECCEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHCCHHHCCCC
QKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIYIDADSSHIETWYIERFLSILKL
CCCCCCCCCEEEEECCHHHCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHH
AKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENLEKFIEPTRNRAELILHKSADHKID
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCH
EIYLKK
HEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]