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The map label for this gene is yehU [C]

Identifier: 21910281

GI number: 21910281

Start: 797725

End: 799374

Strand: Direct

Name: yehU [C]

Synonym: SpyM3_0745

Alternate gene names: 21910281

Gene position: 797725-799374 (Clockwise)

Preceding gene: 21910280

Following gene: 21910282

Centisome position: 41.97

GC content: 35.7

Gene sequence:

>1650_bases
ATGCGAGGTGAACAGGTGGAAGAACATTTTAAAAAACAATTACAAGATGATATTTCTAGACATTTTTCGTACCAATCGTT
AATGTTATCATTGTTGCTAATTGGTCTTTTTATTATTTTTTCATTAGCGCCACAACAATTAGGCCTCTATCGTGATATCA
ATGCCACTGCAACCCGTTATCACCGTTTGATTAGCAAACAAGAAGCCTTGCTGGATGAATTAGGGAAAAATAGCTTACTA
CCTTTTTTAAATAAAAACCTCAGCACTGCTGATTTAAGCAAGCACTATTTTCATTTGCGCCATAGCAGCCAAACGTCACC
AGAACTTTTACTATTTTCACCTAGTCAAGGCCTTTTATTTGCTAGTAACCCACATTTAGGAAATGTTTTTAGTAAATCTG
TTTATATTCAAGAAGTCTTGAGAGCAGCTCATCCTCCAAAAACCTTGTTTAAAGTTGCTATGGATAGTGAAGATGGTCAC
TACTTGATGATCATTAAGCCAATGATTGATCAAAACCAACTAAAGGGATATGCTTTTTTAGTGATGAGTGGCAAAGATTT
TCTTCATCCTACAAAAACATTGACGTCAGAGTTGGTCATTGCTGATAAGCTGGACAACACGTTTACGTTTTCCAATCGTG
AGTTTATAGCATCTAGTCTAGATAAGATCAATAGCCAGTATTTACACCATTATTTTGTTTTTCAAGATAATCGAGCCTTT
ATCACAAGAAAGGTTGCCTTACAAGGAGGTCTTTGGCTTTACATGTATAGGCCCTTGATTCCAATGGTATCGGTGATGTT
ATTTTCACTTATTTCATCAGCTGTTATCTTTGTGATTTTGCAACGTAAATCAAGTGGTTTAGCTAACCGAATTGCAGCTA
AAAATTCAAGAGCAATCAATCAAATGGTTAGAGATATGAGTGCGATCTCTCGGCAAGAAAAAAGACGTATTGACCTTGAG
AGTCAAGATGAATTTCAATATTTATCTGATCAAATCAATCAAATGGTAGAGCGATTGCAACAGTTACATGATAAAACGTT
AGATTTGGAAACTCAAAAATTATTATTTGAAAAACGGATGTTAGAAGCTCAATTCAATCCGCATTTCCTCTACAATACGC
TAGAAACCATTTTGATTACGAGCCATTATGATTCTGCCCTAACAGAAAAAATTGTTATCCAATTGACAAAATTGTTGCGG
TATAGTCTCACGGATTCTAGCAAACCTGTCTTGCTCAAAGATGATTTAAGTGTCATCGAGTCTTATTTAGTGATTAATCA
GGTGCGGTTTGAAGAATTGCAATATAGCATTAACCTATCCTCAGACCTTGATAGTCTTGCAGTGCCTAAATTGTTCTTGT
TACCTTTGATAGAAAATGCCATCAAATATGGCTTGAAAGAACGACACGATGTCAAGATTAACATTGCCTGTTATTATCAA
GATGACCACATTATTTTTTCTGTGCGAGATAATGGTTCGGGAATTGATGCTCATCACCAAAAAGTGATTCGAGAGCAATT
GGAAGCTGGAGAGTCACACCATGGGTTAATTAACTCTTATCGTCGGCTTAAGTATCATTTTTCAGAAGTATCCTTGGTTT
TTGATCAAGGTGATAAACAGTTTAATGTTAGCTACCATGTTAAGGAGTAG

Upstream 100 bases:

>100_bases
TTCTTGTTTTGCTTACCTTTTTCCTTTTAAGATGATGAGACTTGTTTTGATGAAAAATGTAGTAGCATTAAGAAATTTGT
TATAATGAAAGGAGCTTAAG

Downstream 100 bases:

>100_bases
TCTATGTACAAATTAGTCATTATTGAAGATGAACATATTATTAGGAAATGGTTGCGATACGCTATTGATTATAAAGCTTT
AGATATTTTGGTCATTGGCG

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSSDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

Sequences:

>Translated_549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSSDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>Mature_549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSSDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

Specific function: Probable member of the two-component regulatory system SE_0166/SE_0165. May activate SE_0165 by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=149, Percent_Identity=32.8859060402685, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788723, Length=216, Percent_Identity=30.0925925925926, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR010559 [H]

Pfam domain/function: PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63501; Mature: 63501

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
HRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLF
HHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCCEEEECCCCCEEE
ASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFL
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCEEEEEECCCCCCCCCCEEEE
VMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
EECCCCCCCCHHHHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHEEEEEEEECCCEE
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAIN
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
QMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIE
HHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SYLVINQVRFEELQYSINLSSDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCE
FNVSYHVKE
EEEEEEECC
>Mature Secondary Structure
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
HRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLF
HHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCCEEEECCCCCEEE
ASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFL
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCCCEEEEEECCCCCCCCCCEEEE
VMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
EECCCCCCCCHHHHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHEEEEEEEECCCEE
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAIN
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
QMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIE
HHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SYLVINQVRFEELQYSINLSSDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
HHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCE
FNVSYHVKE
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]