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The map label for this gene is clpP [H]

Identifier: 21910248

GI number: 21910248

Start: 768690

End: 769496

Strand: Direct

Name: clpP [H]

Synonym: SpyM3_0712

Alternate gene names: 21910248

Gene position: 768690-769496 (Clockwise)

Preceding gene: 21910247

Following gene: 21910249

Centisome position: 40.45

GC content: 39.65

Gene sequence:

>807_bases
ATGAAGAAGTTGAAACTTAATGGCCCAGTCGTCAGCGAGGGGGACAAGTGGTACTACGATTGGTGGGAAAAACCTTGTAT
TACTGCTAAACAAGTACATGACTTTTTAGACAGTGCGGGTGGAGAAGACATCCAAGTCAGACTAAATTCCGGTGGCGGAG
AGGTTTTTGTAGGTAGTGAAATTTACTCTGCTTTAAAGGATTATCCAGGCAATGTTGAAGTTGTTATCACAGGACTAGCT
GCAAGCATTGCTAGCATCATCATGTTAGCTGGTGATGTTATCAAAGCATCACCGATGGCTCAAATTATGATCCATAACGC
TTCTTGGGGTAGCTATGGAGATTACAGACAGTTAAAACATGACAGCGAAGTTGTTGAAAATGCGAGTATCTCGCTAGCTG
GAATGTACGCTCAAAAAACAGGCAAACAAGAGACTGAAATCAGAGAGTTGCTAGATGCAGAAACATGGTTTACAGCAAAT
AGTGCTAAAGAGATTGGTCTTATTGATGACATTTTATACAATGAGATGCCATCGCTTGTAGCTGGTATTGATATGGTCCC
TAAGGATAAAATCGAGGAATTTAAAAACATGGTTGCTCACGAAAAAGCTCAAACCAATCAGCAAAATGATGACTTTGAAG
CTCGTGTCAAAGCTATTGTAGAGCCAATGATTAACGATTTTAAAAATCGGCCAGTGTCAGAACTTAAAGTATCTATTGAC
GCTGATGAATTAACCGAAGTTATAGGCGATGCGGTGACTGAGATTAAAGAAAAATCCTCATCCCCATTTGCAAAATTTAT
TTTTTAG

Upstream 100 bases:

>100_bases
AGAGAGGAAATTGGTCTTCCTGAGTTGCCAGACGGCTTAGGAAAAGTTCTTTATATGACCAAGAACTATGAATCTGTTCT
GGAGAGAGGAGGTGAAGTAG

Downstream 100 bases:

>100_bases
ACATTAAGGAGAACACATGGCAATTAACTTAAAAGAATTACCAAAATACCGCGAAGCTGTTGCCGAACTGAGCGCAAAAA
TCTCAGCAGGTGCAACACCA

Product: hypothetical protein

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKKLKLNGPVVSEGDKWYYDWWEKPCITAKQVHDFLDSAGGEDIQVRLNSGGGEVFVGSEIYSALKDYPGNVEVVITGLA
ASIASIIMLAGDVIKASPMAQIMIHNASWGSYGDYRQLKHDSEVVENASISLAGMYAQKTGKQETEIRELLDAETWFTAN
SAKEIGLIDDILYNEMPSLVAGIDMVPKDKIEEFKNMVAHEKAQTNQQNDDFEARVKAIVEPMINDFKNRPVSELKVSID
ADELTEVIGDAVTEIKEKSSSPFAKFIF

Sequences:

>Translated_268_residues
MKKLKLNGPVVSEGDKWYYDWWEKPCITAKQVHDFLDSAGGEDIQVRLNSGGGEVFVGSEIYSALKDYPGNVEVVITGLA
ASIASIIMLAGDVIKASPMAQIMIHNASWGSYGDYRQLKHDSEVVENASISLAGMYAQKTGKQETEIRELLDAETWFTAN
SAKEIGLIDDILYNEMPSLVAGIDMVPKDKIEEFKNMVAHEKAQTNQQNDDFEARVKAIVEPMINDFKNRPVSELKVSID
ADELTEVIGDAVTEIKEKSSSPFAKFIF
>Mature_268_residues
MKKLKLNGPVVSEGDKWYYDWWEKPCITAKQVHDFLDSAGGEDIQVRLNSGGGEVFVGSEIYSALKDYPGNVEVVITGLA
ASIASIIMLAGDVIKASPMAQIMIHNASWGSYGDYRQLKHDSEVVENASISLAGMYAQKTGKQETEIRELLDAETWFTAN
SAKEIGLIDDILYNEMPSLVAGIDMVPKDKIEEFKNMVAHEKAQTNQQNDDFEARVKAIVEPMINDFKNRPVSELKVSID
ADELTEVIGDAVTEIKEKSSSPFAKFIF

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=149, Percent_Identity=31.5436241610738, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 29689; Mature: 29689

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKLNGPVVSEGDKWYYDWWEKPCITAKQVHDFLDSAGGEDIQVRLNSGGGEVFVGSE
CCCEECCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECHH
IYSALKDYPGNVEVVITGLAASIASIIMLAGDVIKASPMAQIMIHNASWGSYGDYRQLKH
HHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
DSEVVENASISLAGMYAQKTGKQETEIRELLDAETWFTANSAKEIGLIDDILYNEMPSLV
HHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AGIDMVPKDKIEEFKNMVAHEKAQTNQQNDDFEARVKAIVEPMINDFKNRPVSELKVSID
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECC
ADELTEVIGDAVTEIKEKSSSPFAKFIF
HHHHHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MKKLKLNGPVVSEGDKWYYDWWEKPCITAKQVHDFLDSAGGEDIQVRLNSGGGEVFVGSE
CCCEECCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECHH
IYSALKDYPGNVEVVITGLAASIASIIMLAGDVIKASPMAQIMIHNASWGSYGDYRQLKH
HHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHH
DSEVVENASISLAGMYAQKTGKQETEIRELLDAETWFTANSAKEIGLIDDILYNEMPSLV
HHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
AGIDMVPKDKIEEFKNMVAHEKAQTNQQNDDFEARVKAIVEPMINDFKNRPVSELKVSID
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECC
ADELTEVIGDAVTEIKEKSSSPFAKFIF
HHHHHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]