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The map label for this gene is hemN [H]

Identifier: 21910209

GI number: 21910209

Start: 739369

End: 740595

Strand: Direct

Name: hemN [H]

Synonym: SpyM3_0673

Alternate gene names: 21910209

Gene position: 739369-740595 (Clockwise)

Preceding gene: 21910208

Following gene: 21910210

Centisome position: 38.9

GC content: 37.82

Gene sequence:

>1227_bases
TTGTCAGCTCGTAAAATACTTTTCCAAGCCATGAAGAATCAAGGGAAATGGTTTATTCATAGAAACATTTTATCATCAAA
GTGGTATAATAAGACCATGTCAAAAAAACCTACTTCAGCCTATGTGCACGTTCCTTTTTGCACACAAATTTGTTATTATT
GCGATTTTTCAAAAGTCTTTATCCAAAATCAACCTGTTGATGCTTATTTGAAAGCCTTGATTCAAGAATTTGACTCTTAT
GGCATTCGAGACCTAAAAACCCTTTATATTGGAGGAGGTACGCCTACAGCTATCACTGCTAAACAGTTGGAGTATCTCCT
AAATCACCTTGAACGAAACCTCAATTTAGATGATCTTGAAGAATTCACAATTGAGGCAAATCCTGGTGATTTGACGCCAG
AAAAAATTGCGGTGCTTCAGAGGTCAGCTGTCAATCGGATTTCCTTGGGGGTGCAGACCTTTAATAACAAGCAATTAAAG
CAGATTGGCCGTAGCCATAATGAAGAACAAATTTATAGCACCATCACTAATTTAAAAGCTGCAGGCTTTCACAATATTTC
CATTGATTTAATTTATGCCTTGCCAGGTCAAACCTTAGATCAAGTCAAGGAAAATGTTGCTAAAGCTTTGGCACTTGATA
TTCCCCACCTTAGTCTTTATAGCCTTATTTTGGAACATCACACTGTTTTTATGAACAAAATGCGACGTGGTAAACTTAAC
TTACCAACGGAAGACTTGGAAGCAGAAATGTTTGAGTATATTATTTCAGAAATGGAAGCTAATGGCTTTGAACATTATGA
AATCTCCAATTTTACCAAACCTGGTTTTGAAAGTCGTCATAACTTGATGTATTGGGATAATGTGGAATATTTTGGATGTG
GTGCAGGGGCTTCAGGTTACCTTAATGGCATTCGTTATCAAAATCGGGTGCCCATCCAGCATTATCTTAAAGCGGTTGAA
GCAGGAAACGCTAGACTAAATGAAGAAGTGCTGCGCAAAGAGGAAATGATGGAAGAGGAACTCTTTTTGGGCTTACGTAA
AAAGACAGGAGTCTCCATCCAGCGGTTCCAAGAAAAATTTGGTATTTCTTTTGAGGAGCGTTATGGAAATATTGTTAGGG
AGCTTCAAAACCAAGGACTGCTTGTCAAAGATGACGCTTTTGTCAGAATGACTAAAAAGGGTCTTTTCTTAGGTGATTCT
GTTGCTGAGCGGTTTATATTAGATTAG

Upstream 100 bases:

>100_bases
TTATGGTCAGTCAAGAATCAAGCAAGCTTTTTTACCAAGAACAAGAGTTTGTTTTGCTAGCTAAGGGTTGCAAGCCAGGA
AACGAAAATGATTCTGACGT

Downstream 100 bases:

>100_bases
GAGAGTATTATGGGATTAAGTTATCAGGAGGAGTTGACACTTCCTTTTGAATTATGTGATGTCAAGTCAGATATAAAGTT
GCCCCTTTTATTAGACTATT

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSARKILFQAMKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHVPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSY
GIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLK
QIGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLN
LPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVE
AGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDS
VAERFILD

Sequences:

>Translated_408_residues
MSARKILFQAMKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHVPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSY
GIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLK
QIGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLN
LPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVE
AGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDS
VAERFILD
>Mature_407_residues
SARKILFQAMKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHVPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSYG
IRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQ
IGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNL
PTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEA
GNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSV
AERFILD

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=280, Percent_Identity=31.0714285714286, Blast_Score=158, Evalue=8e-39,
Organism=Escherichia coli, GI1789325, Length=269, Percent_Identity=35.6877323420074, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87082341, Length=384, Percent_Identity=24.7395833333333, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 46988; Mature: 46857

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARKILFQAMKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHVPFCTQICYYCDFSKVF
CCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCHHHH
IQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLE
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
EFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKA
HEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHH
AGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLN
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGY
CCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEECCCCEEECCCCCCHH
LNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKF
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GISFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
CCCHHHHHHHHHHHHHHCCEEEECCHHEEEHHCCCEECHHHHHHHCCC
>Mature Secondary Structure 
SARKILFQAMKNQGKWFIHRNILSSKWYNKTMSKKPTSAYVHVPFCTQICYYCDFSKVF
CHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCHHHH
IQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLE
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
EFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKA
HEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHH
AGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLN
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
LPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGY
CCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCEEEECCCCEEECCCCCCHH
LNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKF
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GISFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
CCCHHHHHHHHHHHHHHCCEEEECCHHEEEHHCCCEECHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]