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The map label for this gene is czcD [H]

Identifier: 21910107

GI number: 21910107

Start: 629537

End: 630412

Strand: Reverse

Name: czcD [H]

Synonym: SpyM3_0571

Alternate gene names: 21910107

Gene position: 630412-629537 (Counterclockwise)

Preceding gene: 21910119

Following gene: 21910084

Centisome position: 33.17

GC content: 33.9

Gene sequence:

>876_bases
ATGCCAGCAAGTAAAAAAGTCACCATTATTTTTATATTAAATCTTAGTTTTTCCCTCATTGAATTTATTTTTGGAACATT
ATTCTTTTCGGGTGCTATTTTAGCAGATGCTGTCCACGATTTTGGAGATGCCATTGCTATTGGTATCTCAGCTATCTTAG
AAAGAAAGGCTGTTAAAAAAGAGAGTCCAAATTTTTCACTAGGCTATAAGCGATTTAGCCTTTTAGGAGCGCTAACGACA
AATCTAATACTTATTAGCGGGTCATTATTAGTAATGATTGAAACGATACCAAAATTATGGCATCCTACTATTGTTAATTA
TGACGGTATGTTCGTTTTAGCTATTTTTGCAATTATAATCAATGGATTTGCTAGCTTCATCATTCACTCTAACCAGACAA
AAAATGAAGAAATATTAAGCCTTCACTTTTTAGAAGATATCCTTGGATGGTTAGCCATTATCATACTGTCACTGATCTTA
AAATGGAAACCTTGGTACATTCTTGATCCTTTATTATCAATTGCCATTGCTTCTTTTATATTATCTAAAGCTCTTCCAAA
GTTAGTAGCAACCGCTAACATTTTTTTAGATGGTGTTCCTGATTCGATAGACTATTGCGCTTTGCACCATGAACTCAGCC
AACTTCCTCATATAGTGTCTGTTAATCAGCTTAATGTTTGGTCGATGGATGGTATTGACCATAGAGCAACTATACATTGC
TGCTTGAGAAAATCCACCACTGAAAAACATTGCAAAAAATCTATTAGACTGATTTGTCAAAGGTACAATATAAACTCAGT
CACTGTGGAAATCGATACTTCTTTAAACGAACACCAACATCACTGTTCTTCTCTTTCTAGTATTGAAGTCAACTAA

Upstream 100 bases:

>100_bases
AGGTGCTCATTTTTGGTTATAGTAATTGTATTTTAACTTCTAGATAATAGAATAAAGAATTCTACTATACATATTACCAG
TATAACAAAAGGAGAAAATT

Downstream 100 bases:

>100_bases
TTGAAGTCAATTAATGTGCTATAAGTCTATTGAAAACTTATTAGGTGCAGTTATCTATAAATATTAAGAGCACCTAATAA
GCATACCCCTTTTTACAACA

Product: putative cation-efflux system membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDAIAIGISAILERKAVKKESPNFSLGYKRFSLLGALTT
NLILISGSLLVMIETIPKLWHPTIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHIVSVNQLNVWSMDGIDHRATIHC
CLRKSTTEKHCKKSIRLICQRYNINSVTVEIDTSLNEHQHHCSSLSSIEVN

Sequences:

>Translated_291_residues
MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDAIAIGISAILERKAVKKESPNFSLGYKRFSLLGALTT
NLILISGSLLVMIETIPKLWHPTIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHIVSVNQLNVWSMDGIDHRATIHC
CLRKSTTEKHCKKSIRLICQRYNINSVTVEIDTSLNEHQHHCSSLSSIEVN
>Mature_290_residues
PASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDAIAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTN
LILISGSLLVMIETIPKLWHPTIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLILK
WKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHIVSVNQLNVWSMDGIDHRATIHCC
LRKSTTEKHCKKSIRLICQRYNINSVTVEIDTSLNEHQHHCSSLSSIEVN

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI21359890, Length=314, Percent_Identity=22.2929936305732, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786966, Length=280, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32564488, Length=303, Percent_Identity=21.1221122112211, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210990, Length=294, Percent_Identity=22.108843537415, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17555794, Length=310, Percent_Identity=22.258064516129, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555796, Length=310, Percent_Identity=22.258064516129, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 32464; Mature: 32332

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDAIAIGISAILERKAVKK
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHPTIVNYDGMFVLAIFAIII
CCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
NGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLILKWKPWYILDPLLSIAIASFI
HHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHIVSVNQLNVWSMDGIDHRATIHC
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHH
CLRKSTTEKHCKKSIRLICQRYNINSVTVEIDTSLNEHQHHCSSLSSIEVN
HHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDAIAIGISAILERKAVKK
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHPTIVNYDGMFVLAIFAIII
CCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
NGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLILKWKPWYILDPLLSIAIASFI
HHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHIVSVNQLNVWSMDGIDHRATIHC
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHH
CLRKSTTEKHCKKSIRLICQRYNINSVTVEIDTSLNEHQHHCSSLSSIEVN
HHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA