Click here to switch to the map view.

The map label for this gene is cdh

Identifier: 218930981

GI number: 218930981

Start: 4490555

End: 4491331

Strand: Direct

Name: cdh

Synonym: YPO3986

Alternate gene names: 218930981

Gene position: 4490555-4491331 (Clockwise)

Preceding gene: 218930980

Following gene: 218930984

Centisome position: 96.49

GC content: 50.58

Gene sequence:

>777_bases
GTGTCACGCTCAATAAAATGGCGTAGATACTTACTGACATTGCTGATCTTGATCATACTGGCTGCAGGCCTGATTTATAA
ATTACGTTTCAGTAATGCGGATGCACTCTGGAAGATCATTAGCCAGCAATGTATTCCGCATATGACCACAGAAGATGATC
CGCGCCCTTGTGCCGAGGTGAATATACCCGCGGGCTTTGCGGTGCTTAAAGATAGGAATGGCCCGTTACAGTATTTGTTG
ATCCCCACCGTACCCATTAGCGGTATTGAAAGCCCGCAATTATTAACCGCCACCAGCCCGAACTATTTTGCCGACGCTTG
GCAGGCTCGCTATTTTATGGCTGAGAAGTACGGCGCGCCTATCGATGACACTGATATCTCATTAGCCATCAATTCGCAAT
ATGGGCGCACACAGGATCAATTGCACATTCATATCTCTTGTCTGAAGCCACAAGTAAAAACCGCACTGGCCGCCCATAGC
GCCGATTTCCAGCAACAATGGCAGCCGCTGCCTGGCGGCTTACTGGGACACGATTATTGGGTACGGCGCATCACAGCAAC
CGAATTGCAACAACCAGGGCCGTTTCATCTGTTAGCCGATGAAATGCCAGGGGCAAAAGAACAGATGGGCCGTTACGGTC
TGGCAATAACCGCACTACCCTCTGGGGATTTTTTACTGCTGGCCAACAAAGCAAGCCTGATAACCCAGGATCGCGCCTCA
GCAGAGGAGCTGCAAGATCACACCTGTCAGGTGCTACCTCACCTCCCGGTGCAATAA

Upstream 100 bases:

>100_bases
TAAAGACATTGAGGATAAGAATATTGAGGACCAAAACGTAGAAGACAAGAGTTTACCAACACGTGGAGAAAAGTAACTTA
TGATTATGAAAAAATCATCA

Downstream 100 bases:

>100_bases
CACATTATTTCTTTTGCTGTATTTTTCGCAGTAACGGGGCGCACTGATTCTCTTCACCTTCACCTTCACTGGGGAGATCA
GTGCCAGTAATGCCGCTGCC

Product: CDP-diacylglycerol pyrophosphatase

Products: NA

Alternate protein names: CDP-diacylglycerol phosphatidylhydrolase; CDP-diglyceride hydrolase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSRSIKWRRYLLTLLILIILAAGLIYKLRFSNADALWKIISQQCIPHMTTEDDPRPCAEVNIPAGFAVLKDRNGPLQYLL
IPTVPISGIESPQLLTATSPNYFADAWQARYFMAEKYGAPIDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTALAAHS
ADFQQQWQPLPGGLLGHDYWVRRITATELQQPGPFHLLADEMPGAKEQMGRYGLAITALPSGDFLLLANKASLITQDRAS
AEELQDHTCQVLPHLPVQ

Sequences:

>Translated_258_residues
MSRSIKWRRYLLTLLILIILAAGLIYKLRFSNADALWKIISQQCIPHMTTEDDPRPCAEVNIPAGFAVLKDRNGPLQYLL
IPTVPISGIESPQLLTATSPNYFADAWQARYFMAEKYGAPIDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTALAAHS
ADFQQQWQPLPGGLLGHDYWVRRITATELQQPGPFHLLADEMPGAKEQMGRYGLAITALPSGDFLLLANKASLITQDRAS
AEELQDHTCQVLPHLPVQ
>Mature_257_residues
SRSIKWRRYLLTLLILIILAAGLIYKLRFSNADALWKIISQQCIPHMTTEDDPRPCAEVNIPAGFAVLKDRNGPLQYLLI
PTVPISGIESPQLLTATSPNYFADAWQARYFMAEKYGAPIDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTALAAHSA
DFQQQWQPLPGGLLGHDYWVRRITATELQQPGPFHLLADEMPGAKEQMGRYGLAITALPSGDFLLLANKASLITQDRASA
EELQDHTCQVLPHLPVQ

Specific function: Phospholipid biosynthesis. [C]

COG id: COG2134

COG function: function code I; CDP-diacylglycerol pyrophosphatase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cdh family

Homologues:

Organism=Escherichia coli, GI1790352, Length=243, Percent_Identity=51.0288065843621, Blast_Score=266, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDH_YERPE (Q8ZA34)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AC0485
- RefSeq:   NP_671137.1
- RefSeq:   NP_994637.1
- RefSeq:   YP_002348856.1
- ProteinModelPortal:   Q8ZA34
- SMR:   Q8ZA34
- IntAct:   Q8ZA34
- GeneID:   1148790
- GeneID:   1176824
- GeneID:   2764894
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3986
- KEGG:   ypk:y3843
- KEGG:   ypm:YP_3349
- HOGENOM:   HBG565233
- OMA:   EIQDHEC
- ProtClustDB:   PRK05471
- BioCyc:   YPES187410:Y3843-MONOMER
- BioCyc:   YPES214092:YPO3986-MONOMER
- BRENDA:   3.6.1.26
- HAMAP:   MF_00319
- InterPro:   IPR003763
- PIRSF:   PIRSF001273

Pfam domain/function: PF02611 CDH

EC number: =3.6.1.26

Molecular weight: Translated: 28779; Mature: 28648

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18e05e24)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSIKWRRYLLTLLILIILAAGLIYKLRFSNADALWKIISQQCIPHMTTEDDPRPCAEV
CCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEE
NIPAGFAVLKDRNGPLQYLLIPTVPISGIESPQLLTATSPNYFADAWQARYFMAEKYGAP
ECCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
IDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTALAAHSADFQQQWQPLPGGLLGHDYW
CCCCCEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
VRRITATELQQPGPFHLLADEMPGAKEQMGRYGLAITALPSGDFLLLANKASLITQDRAS
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCEEEEEECCCCEEEEECCCHHHCCCCCC
AEELQDHTCQVLPHLPVQ
HHHHHHHHHHCCCCCCCH
>Mature Secondary Structure 
SRSIKWRRYLLTLLILIILAAGLIYKLRFSNADALWKIISQQCIPHMTTEDDPRPCAEV
CCCHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEE
NIPAGFAVLKDRNGPLQYLLIPTVPISGIESPQLLTATSPNYFADAWQARYFMAEKYGAP
ECCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
IDDTDISLAINSQYGRTQDQLHIHISCLKPQVKTALAAHSADFQQQWQPLPGGLLGHDYW
CCCCCEEEEEECCCCCCCCEEEEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHH
VRRITATELQQPGPFHLLADEMPGAKEQMGRYGLAITALPSGDFLLLANKASLITQDRAS
HHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCCEEEEEECCCCEEEEECCCHHHCCCCCC
AEELQDHTCQVLPHLPVQ
HHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430