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The map label for this gene is fbaA [H]

Identifier: 218930956

GI number: 218930956

Start: 4457252

End: 4458112

Strand: Reverse

Name: fbaA [H]

Synonym: YPO3960

Alternate gene names: 218930956

Gene position: 4458112-4457252 (Counterclockwise)

Preceding gene: 218930957

Following gene: 218930955

Centisome position: 95.8

GC content: 51.45

Gene sequence:

>861_bases
ATGGCTTTGATTTCCCTTGCAAATGGCCTGGCTCATGCCAGGAAAAACGGTTACGCATTGGGTGCCTTTAACGTGCTCGA
TAGCCACTTTTTGCGCGCCCTGTTTGCCGCTGCAAAACAGGAACGATCGCCGTTTATCATCAATATTGCTGAAGTCCATT
TTAAGTACCTTTCGCTAGAATCATTGGTAGAAGCAGTGAAATTCGAAGCTGCACACCATGATATCCCGGTGGTGCTTAAT
CTCGACCACGGCCTGCACTTTGAAGCCGTGGTTCGCGCACTCAGGCTGGGTTTTAGCTCGGTAATGTTTGATGGTTCCAC
GCTTGAATATGAAGAAAACGTTCGCCAAACCCGTGAAGTTGTGAAGATGTGCCATGCCGTGGGTGTATCGGTAGAAGCTG
AACTGGGCGCTGTTGGCGGTGATGAAGGCGGCGCGCTTTATGGTGAAGCTGATAGCAATAAATTCACTGATCCCGCTATC
GCCCGGGACTTTGTTGACCGTACCGGTATCGATGCCTTAGCGGTCGCCATCGGCAACGCACACGGCAAGTATAAAGGTGA
ACCCAAGCTCGACTTCGCGCGTCTGGCCGCCATTCATCAGCAAACCGGCCTACCTCTGGTACTGCACGGTGGCTCTGGGA
TCAGCGATACCGATTTCCGGCGGGCTATCAGCCTTGGCATTCATAAAATCAATTTTTATACCGGCATGTCGCAGGCAGCG
CTGGCTGCCGTGGAACAGAAAATGACTCATCGACACGCTATTTATGACGAGTTCGCCGAGTTGTTCCTGGGGATCGAGGA
GGCTATTACTGATGTCGTAGCGCAACAAATGCGAATTTTCGGCAGTTCAGAGCAAATCTGA

Upstream 100 bases:

>100_bases
GAACGTTTTAATTCGATTATTGAAGACGAACCGGCTGAACTTGTGCTGTGTAATGAGTACTGCCGTTTCGTCTGAATTTG
CCAACACCAGGAGAACGACT

Downstream 100 bases:

>100_bases
GAGGATGCCATGATAGAACGCAACGGGATTATTGCCGCCGGTAATATGTTGGTCGACCATGTTCATCAAATTGAGCAATG
GCCGCAGCGTGGTTGGCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MALISLANGLAHARKNGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYLSLESLVEAVKFEAAHHDIPVVLN
LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPAI
ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDTDFRRAISLGIHKINFYTGMSQAA
LAAVEQKMTHRHAIYDEFAELFLGIEEAITDVVAQQMRIFGSSEQI

Sequences:

>Translated_286_residues
MALISLANGLAHARKNGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYLSLESLVEAVKFEAAHHDIPVVLN
LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPAI
ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDTDFRRAISLGIHKINFYTGMSQAA
LAAVEQKMTHRHAIYDEFAELFLGIEEAITDVVAQQMRIFGSSEQI
>Mature_285_residues
ALISLANGLAHARKNGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYLSLESLVEAVKFEAAHHDIPVVLNL
DHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPAIA
RDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDTDFRRAISLGIHKINFYTGMSQAAL
AAVEQKMTHRHAIYDEFAELFLGIEEAITDVVAQQMRIFGSSEQI

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=275, Percent_Identity=38.9090909090909, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1789526, Length=286, Percent_Identity=37.0629370629371, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1788072, Length=271, Percent_Identity=38.7453874538745, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789293, Length=279, Percent_Identity=24.7311827956989, Blast_Score=75, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322790, Length=287, Percent_Identity=28.2229965156794, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 31061; Mature: 30929

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLANGLAHARKNGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYLSLE
CCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SLVEAVKFEAAHHDIPVVLNLDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREV
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHH
VKMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPAIARDFVDRTGIDALAVAIGNA
HHHHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
HGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDTDFRRAISLGIHKINFYTGMSQAA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCHHHHH
LAAVEQKMTHRHAIYDEFAELFLGIEEAITDVVAQQMRIFGSSEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALISLANGLAHARKNGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYLSLE
CHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SLVEAVKFEAAHHDIPVVLNLDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREV
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHEECCCCCCHHHHHHHHHHH
VKMCHAVGVSVEAELGAVGGDEGGALYGEADSNKFTDPAIARDFVDRTGIDALAVAIGNA
HHHHHHHCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
HGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDTDFRRAISLGIHKINFYTGMSQAA
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCHHHHH
LAAVEQKMTHRHAIYDEFAELFLGIEEAITDVVAQQMRIFGSSEQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2457578; 1640835; 9353933; 9384377; 1556067 [H]