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The map label for this gene is trkH [H]

Identifier: 218930767

GI number: 218930767

Start: 4224353

End: 4225804

Strand: Reverse

Name: trkH [H]

Synonym: YPO3762

Alternate gene names: 218930767

Gene position: 4225804-4224353 (Counterclockwise)

Preceding gene: 218930768

Following gene: 218930766

Centisome position: 90.8

GC content: 46.56

Gene sequence:

>1452_bases
ATGCATTTTCGTGCCATAACCCGTATTGTTGGTCTGCTGGTCATCTTATTCTCCGGAACAATGTTTATTCCCGGGCTGGT
GGCTTTGATCTATCGTGATGGTGCTGGCCGTGCCTTCAGTGAAACTTTTTTTGTTGCTGTGTCTATCGGGCTTTTGCTTT
GGTTACCGAATAGAAAGCAGAAGCATGAGTTAAAACCTCGCGAGGGTTTTCTCATCGTCGTATTATTTTGGACGGTGTTG
GGTAGTGTCGGGGCATTACCTTTTTTATTCTCAGAGCGGCCTAATCTTTCATTAACTGATGCATTCTTTGAATCATTCTC
AGGGTTAACTACCACAGGGGCAACTACCTTAGTGGGGTTGGATTCACTTCCCAAAGCAATTCTATTCTATCGACAAATGC
TGCAATGGCTTGGTGGGATGGGGATCATCGTACTCGCTGTGGCTATTTTGCCAATTTTGGGCGTCGGGGGGATGCAGCTC
TATCGTGCAGAAATGCCTGGTCCGCTGAAAGATAATAAAATGCGGCCCCGCATTGCTGAAACGGCTAAAACGCTCTGGCT
CATCTATGTACTACTGACTATCGCTTGTGCGCTTGCCCTTTGGGGAGCAGGGATGTCGGTATTTGATGCTATTTCTCATA
GTTTTTCGACAATAGCTATCGGTGGTTTTTCAACCCATGATGCCAGCATTGGGTACTTTAACAGCCCAACGATCAACACA
ATTATTGGCATATTCTTGCTGATTTCTGGCTGTAATTTTGGTTTACACTTTGCGGTACTCAGTGGCAGAAGCTTGAAAGT
CTATTGGCGTGATCCCGAATTCCGTATGTTTATCTTTGTACAATTGACGCTAGTTATCGTTTGTACCTTAGTGCTCTGGC
AACATAGTGTATATAAGTCCGGAATAGAAACCTTAAATCAGGCGTTCTTCCAAGTGGTTTCAATGGCTACTACGGCGGGC
TTCACGACCGACAGCATTGCGAAATGGCCGCTCTTCTTGCCCCTACTCTTATTATGTTCTGCTTTTATTGGTGGTTGTGC
GGGGTCTACCGGGGGCGGCCTAAAAGTTATTCGTATCCTATTACTCTACTTACAAGGTTCACGCGAGTTAAAACGGTTGG
TCCACCCTAATGCGGTTTACACCATTAAACTGGGGCGGCGTGCATTACCCGAGCGGATTCTTGAAGCGGTTTGGGGCTTT
TTCTCTGCTTATGCGCTGGTCTTCATTATCAGTATGTTAGCGATCGTCGCGACTGGGGTTGATGAATTTTCTGCCTTCGC
TGCTGTCACTGCGACGTTGAATAACCTCGGGCCCGGTTTGGGGGTAGTGGCTGATAACTTTACATCTATGAATCCCGCAG
CCAAATGGATATTGGTGATTACGATGTTATTTGGCCGGCTGGAAGTCTTCACTTTGCTAGTCCTTTTCACCCCAACATTT
TGGCGCGAGTAG

Upstream 100 bases:

>100_bases
AGTCGGGGATAAATTGCGTGATCTCAGTCGTGGTACATTGCAATTAACACCTATTTCGTAATAATCCCCATCCAAGTGAA
TTGCTAAGGAACGTGCCGGA

Downstream 100 bases:

>100_bases
TTCTGCATAAGGAACATTACTATGAAAATACTAATACTTTACTCCAGCCGAGACGGCCAAACGAAAACTATAGCTTCTTA
TATAGCTAAGCAATTAACAG

Product: potassium transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSETFFVAVSIGLLLWLPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWLGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAISHSFSTIAIGGFSTHDASIGYFNSPTINT
IIGIFLLISGCNFGLHFAVLSGRSLKVYWRDPEFRMFIFVQLTLVIVCTLVLWQHSVYKSGIETLNQAFFQVVSMATTAG
FTTDSIAKWPLFLPLLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGRRALPERILEAVWGF
FSAYALVFIISMLAIVATGVDEFSAFAAVTATLNNLGPGLGVVADNFTSMNPAAKWILVITMLFGRLEVFTLLVLFTPTF
WRE

Sequences:

>Translated_483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSETFFVAVSIGLLLWLPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWLGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAISHSFSTIAIGGFSTHDASIGYFNSPTINT
IIGIFLLISGCNFGLHFAVLSGRSLKVYWRDPEFRMFIFVQLTLVIVCTLVLWQHSVYKSGIETLNQAFFQVVSMATTAG
FTTDSIAKWPLFLPLLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGRRALPERILEAVWGF
FSAYALVFIISMLAIVATGVDEFSAFAAVTATLNNLGPGLGVVADNFTSMNPAAKWILVITMLFGRLEVFTLLVLFTPTF
WRE
>Mature_483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSETFFVAVSIGLLLWLPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWLGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAISHSFSTIAIGGFSTHDASIGYFNSPTINT
IIGIFLLISGCNFGLHFAVLSGRSLKVYWRDPEFRMFIFVQLTLVIVCTLVLWQHSVYKSGIETLNQAFFQVVSMATTAG
FTTDSIAKWPLFLPLLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGRRALPERILEAVWGF
FSAYALVFIISMLAIVATGVDEFSAFAAVTATLNNLGPGLGVVADNFTSMNPAAKWILVITMLFGRLEVFTLLVLFTPTF
WRE

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=88.6128364389234, Blast_Score=826, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=41.701244813278, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52967; Mature: 52967

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSETFFVAVSIGLLLWLPNRKQ
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KHELKPREGFLIVVLFWTVLGSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
DSLPKAILFYRQMLQWLGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWGAGMSVFDAISHSFSTIAIGGFSTHDASIGYFNSPTINT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
IIGIFLLISGCNFGLHFAVLSGRSLKVYWRDPEFRMFIFVQLTLVIVCTLVLWQHSVYKS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
GIETLNQAFFQVVSMATTAGFTTDSIAKWPLFLPLLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLYLQGSRELKRLVHPNAVYTIKLGRRALPERILEAVWGFFSAYALVFIISMLAIVATGV
HHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DEFSAFAAVTATLNNLGPGLGVVADNFTSMNPAAKWILVITMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC
>Mature Secondary Structure
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSETFFVAVSIGLLLWLPNRKQ
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KHELKPREGFLIVVLFWTVLGSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
DSLPKAILFYRQMLQWLGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWGAGMSVFDAISHSFSTIAIGGFSTHDASIGYFNSPTINT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHH
IIGIFLLISGCNFGLHFAVLSGRSLKVYWRDPEFRMFIFVQLTLVIVCTLVLWQHSVYKS
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
GIETLNQAFFQVVSMATTAGFTTDSIAKWPLFLPLLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLYLQGSRELKRLVHPNAVYTIKLGRRALPERILEAVWGFFSAYALVFIISMLAIVATGV
HHHHCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DEFSAFAAVTATLNNLGPGLGVVADNFTSMNPAAKWILVITMLFGRLEVFTLLVLFTPTF
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]