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The map label for this gene is malE [H]

Identifier: 218930720

GI number: 218930720

Start: 4147824

End: 4149035

Strand: Direct

Name: malE [H]

Synonym: YPO3714

Alternate gene names: 218930720

Gene position: 4147824-4149035 (Clockwise)

Preceding gene: 218930714

Following gene: 218930721

Centisome position: 89.13

GC content: 48.6

Gene sequence:

>1212_bases
ATGACTCGCAGCTTCACGAAATCCGGCATTGGTAAGACCGCACGTGTTTTGGCTCTTTCGGCGTTAACCACGCTGGTGCT
CTCTTCCTCTGCTTTTGCCAAAATTGAAGAAGGTAAACTGGTTATCTGGATCAATGGCGATAAAGGTTATAACGGATTGG
CAGAGGTCGGTAAGAAATTTGAGAAAGATACCGGCATCAAAGTGACCATCGAGCATCCAGATAAATTGGAAGAAAAATTC
CCACAAGTCGCCGCAACCGGTGATGGCCCGGACATTATCTTCTGGGCCCATGACCGTTTTGGTGGCTATGCACAATCAGG
TTTACTGGCTGAACTGACCCCATCGAAAGCCTTCCAGGAAAAATTGTTCCCATTCACTTGGGATGCCGTTCGCTTTAATG
GCAAGCTGATTGGTTACCCTGTTGCAGTCGAAGCGCTGTCACTGATTTACAACAAAGATCTGGTGAAAGAAGCACCAAAA
ACGTGGGAAGAGATCCCTGCACTGGATAAAACACTGCGTGCTAATGGCAAAAGCGCCATTATGTGGAACCTACAAGAACC
GTACTTCACTTGGCCCGTTATCGCCGCTGATGGCGGTTATGCATTCAAGTTTGAAAACGGGGTTTATGATGCGAAGAACG
TGGGCGTAAATAATGCGGGCGCCCAAGCTGGCCTACAATTTATTGTCGATCTCGTTAAGAATAAGCACATCAATGCCGAT
ACTGATTACTCCATCGCAGAAGCAGCCTTTAATAAAGGTGAAACCGCGATGACCATTAATGGCCCATGGGCATGGTCCAA
TATCGATAAGAGTAAAATTAATTACGGCGTAACCCTGCTGCCAACCTTCCATGGCCAGCCATCTAAACCCTTTGTCGGTG
TACTGACCGCCGGTATTAACGCAGCGAGTCCAAATAAAGAACTGGCAACGGAATTCCTGGAAAACTATCTGATCACCGAC
CAAGGCCTGGCTGAGGTCAACAAAGATAAACCACTGGGTGCCGTAGCGCTGAAATCATTCCAGGAGCAACTGGCAAAAGA
TCCGCGGATTGCAGCAACAATGGATAACGCCACCAACGGCGAAATCATGCCAAACATTCCGCAAATGGCAGCCTTCTGGT
ATGCCACCCGTAGTGCGGTACTGAACGCCATCACTGGGCGTCAAACCGTTGAAGCGGCACTGAACGATGCGGCAACCCGT
ATCACGAAGTAA

Upstream 100 bases:

>100_bases
CCTTCTACTTCGTGATTCATGGCGATAGCAGTCTGAAAATTCGCAGCTAATGGCTCACAAGAAAGTCGGTACCCACAAAA
TTGGATAAAAGGATTGGATT

Downstream 100 bases:

>100_bases
CTGTCTACTCTGAGAAAGGGGCACGGTTCGCCGTGCCTCGACAGAATTTGCCATAACGCGATCCAATGTTAAGCACAGCT
CAACGTTAAACACGACCCAA

Product: maltose ABC transporter periplasmic protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: MMBP; Maltodextrin-binding protein [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTRSFTKSGIGKTARVLALSALTTLVLSSSAFAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTIEHPDKLEEKF
PQVAATGDGPDIIFWAHDRFGGYAQSGLLAELTPSKAFQEKLFPFTWDAVRFNGKLIGYPVAVEALSLIYNKDLVKEAPK
TWEEIPALDKTLRANGKSAIMWNLQEPYFTWPVIAADGGYAFKFENGVYDAKNVGVNNAGAQAGLQFIVDLVKNKHINAD
TDYSIAEAAFNKGETAMTINGPWAWSNIDKSKINYGVTLLPTFHGQPSKPFVGVLTAGINAASPNKELATEFLENYLITD
QGLAEVNKDKPLGAVALKSFQEQLAKDPRIAATMDNATNGEIMPNIPQMAAFWYATRSAVLNAITGRQTVEAALNDAATR
ITK

Sequences:

>Translated_403_residues
MTRSFTKSGIGKTARVLALSALTTLVLSSSAFAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTIEHPDKLEEKF
PQVAATGDGPDIIFWAHDRFGGYAQSGLLAELTPSKAFQEKLFPFTWDAVRFNGKLIGYPVAVEALSLIYNKDLVKEAPK
TWEEIPALDKTLRANGKSAIMWNLQEPYFTWPVIAADGGYAFKFENGVYDAKNVGVNNAGAQAGLQFIVDLVKNKHINAD
TDYSIAEAAFNKGETAMTINGPWAWSNIDKSKINYGVTLLPTFHGQPSKPFVGVLTAGINAASPNKELATEFLENYLITD
QGLAEVNKDKPLGAVALKSFQEQLAKDPRIAATMDNATNGEIMPNIPQMAAFWYATRSAVLNAITGRQTVEAALNDAATR
ITK
>Mature_402_residues
TRSFTKSGIGKTARVLALSALTTLVLSSSAFAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTIEHPDKLEEKFP
QVAATGDGPDIIFWAHDRFGGYAQSGLLAELTPSKAFQEKLFPFTWDAVRFNGKLIGYPVAVEALSLIYNKDLVKEAPKT
WEEIPALDKTLRANGKSAIMWNLQEPYFTWPVIAADGGYAFKFENGVYDAKNVGVNNAGAQAGLQFIVDLVKNKHINADT
DYSIAEAAFNKGETAMTINGPWAWSNIDKSKINYGVTLLPTFHGQPSKPFVGVLTAGINAASPNKELATEFLENYLITDQ
GLAEVNKDKPLGAVALKSFQEQLAKDPRIAATMDNATNGEIMPNIPQMAAFWYATRSAVLNAITGRQTVEAALNDAATRI
TK

Specific function: Involved in the high-affinity maltose membrane transport system malEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides [H]

COG id: COG2182

COG function: function code G; Maltose-binding periplasmic proteins/domains

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790466, Length=390, Percent_Identity=84.6153846153846, Blast_Score=697, Evalue=0.0,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006060
- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 43829; Mature: 43698

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSFTKSGIGKTARVLALSALTTLVLSSSAFAKIEEGKLVIWINGDKGYNGLAEVGKKF
CCCCCCHHCCCHHHHHHHHHHHHHHHHCCCHHEEEECCEEEEEEECCCCCCHHHHHHHHH
EKDTGIKVTIEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAELTPSKAFQE
HCCCCCEEEECCCHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHCCEEEECCCCHHHHH
KLFPFTWDAVRFNGKLIGYPVAVEALSLIYNKDLVKEAPKTWEEIPALDKTLRANGKSAI
HCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
MWNLQEPYFTWPVIAADGGYAFKFENGVYDAKNVGVNNAGAQAGLQFIVDLVKNKHINAD
EEECCCCCEEEEEEEECCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TDYSIAEAAFNKGETAMTINGPWAWSNIDKSKINYGVTLLPTFHGQPSKPFVGVLTAGIN
CCCHHHHHHHCCCCEEEEECCCEEECCCCHHHCCCCEEEEEECCCCCCCCEEEEEECCCC
AASPNKELATEFLENYLITDQGLAEVNKDKPLGAVALKSFQEQLAKDPRIAATMDNATNG
CCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
EIMPNIPQMAAFWYATRSAVLNAITGRQTVEAALNDAATRITK
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRSFTKSGIGKTARVLALSALTTLVLSSSAFAKIEEGKLVIWINGDKGYNGLAEVGKKF
CCCCCHHCCCHHHHHHHHHHHHHHHHCCCHHEEEECCEEEEEEECCCCCCHHHHHHHHH
EKDTGIKVTIEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAELTPSKAFQE
HCCCCCEEEECCCHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHCCEEEECCCCHHHHH
KLFPFTWDAVRFNGKLIGYPVAVEALSLIYNKDLVKEAPKTWEEIPALDKTLRANGKSAI
HCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
MWNLQEPYFTWPVIAADGGYAFKFENGVYDAKNVGVNNAGAQAGLQFIVDLVKNKHINAD
EEECCCCCEEEEEEEECCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TDYSIAEAAFNKGETAMTINGPWAWSNIDKSKINYGVTLLPTFHGQPSKPFVGVLTAGIN
CCCHHHHHHHCCCCEEEEECCCEEECCCCHHHCCCCEEEEEECCCCCCCCEEEEEECCCC
AASPNKELATEFLENYLITDQGLAEVNKDKPLGAVALKSFQEQLAKDPRIAATMDNATNG
CCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
EIMPNIPQMAAFWYATRSAVLNAITGRQTVEAALNDAATRITK
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]