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The map label for this gene is yhcP [H]

Identifier: 218930695

GI number: 218930695

Start: 4120160

End: 4122115

Strand: Direct

Name: yhcP [H]

Synonym: YPO3686

Alternate gene names: 218930695

Gene position: 4120160-4122115 (Clockwise)

Preceding gene: 218930694

Following gene: 218930696

Centisome position: 88.53

GC content: 50.31

Gene sequence:

>1956_bases
ATGACCCACCCAAGCTTTATTCGCCTGCGGTTTGCGTTCAAGCTGAGTTTTGCCATTGTGGCGGCATTATTTCTTGGCTT
TCATCTGCAATTGGAAACACCGCGTTGGTCAGTGCTTACTGCCGCTATTGTTTCCGCCGGGCCTGCCTTCGCTGCAGGTG
GCGAACCTTTCTCTGGTGCGATTCGCCACCGAGGTTGGTTACGGATTATCGGCACCTTTATCGGCTGTATTGGGGGGCTG
GTCATTATTGTGCTGACCATCAGAGCGCCAGTATTAACGTTGATGCTGTGTTGCCTATGGGCTGGGATCTGTACGTGGAT
TTCATCACTGGTACGGGTAGAAAATTCGTATGCGTTCGGTTTGGCCGGTTATACCGCGTTAATCATCATTGTCACCACCG
GTGAAACGCCACTACTGACGCCGCAATTTGCGGTTGAGCGCTGTAGCGAAATTGTCCTCGGGATCGTCTGTGCGGTGATG
GCAGATCTGCTGTTTTCACCCCGCTCGATCAAACAGGATATTGATCGATTGGTCGACAAGGTGTTAGTGGATCAGTACCG
GCTCTTACAACTCTGCATTCAGCCAGCAGAAAAAAGTGAGATTGATCGCGCTTGGAATGAATTGGTTAAAAATACCACGT
CACTCAATGGGATGCGCAGCTATCTGATGATGGAGTCTTCCCGTTGGCAGCGGTGTAATCGCCGTTTGCAGGTGTTACAT
ACCGAGTCTTTGGCGCTGATCACGCAGGCGTGTGAAACCTATCTGGTGATGAGCAATCACCCAGAGGTGATCAGTGCTGA
ACTGAAAACTATGCTGAGCGAACCCGCTCAAACTCCTGCAGAGATCCACCAGCAGATGAAAAAACTGCGTCAGTTTATTG
CTGCCAGCCACAGTGAGGCGATCCCGCACACCATCAGCAGTTGGGTTGGGGCAGCGACTCGCTATTTATTACTGTCGAAA
GGGATCCAGACCAACAGCAGCATCAATCAGGTCGAAGAGGATATTTTGGCGGGTGATGCGCCGGTTAAGCCCATTTCTGC
CGAAGGCCATCATGCGATGATCAATGGCTTGCGTACCGGTATTGCCACGGCGATTGGTGGCCTGTTCTGGCTGTGGACCG
GCTGGACATCCGGCGCGGGGTGTATGGTGATGATTGCAGTGGTCACTTCGCTGGCGATGCGAACACCGAATCCACGGAGG
ATGGCGCTCGATTTTCTGGTCGGCGTGATTATCGCACTGCCCATCGGGGCGCTTTACTTTATGTTTATTATCCCGTCGAC
CCAGCAAAGTATGCTGTTGCTCTGTATCAGCTTGGGGGTGCTGGCATTTATTATCGGCATCGAAGTACAAAAACGGCGCT
TGGGTTCACTGGGAACGCTGGCTAGCACCATAAATATTATCGTGCTAAGTAATCCAATGATATTTAATGTCCGCCAGTTT
CTCGATAGCGCATTAGGTCAAATTGTAGGCTGCTTTGTCTCTTTAATTGTCCTGCTGTTGATCCGTGACAACGCGAAGGA
CAGAACGGGCAGAACCTTACTCAACCGTTTTGTTTACAGTGCGGTCTCGGCCCTAACCACCAATAAAACCAAGCGCGGCG
AAAATCATCTACCCGCGCTGTATCAGCAACTGAACCAGTTATTGATGATGTTCCCGGCCGATATTGATAAATATCGTCTG
GCATTAACGCTGATTATTGCTCACCAGCGGTTAAACAGGACTGAAATCCCGGTGAATGCGGAGTTGAGCGCTTTTCATAA
ACAGATCCGCTCTACCGCAGAGCGAGTGATTACTGTCAACAATGACCAGAAACGGCGTTATTATTTTGCCCGGTTATTGC
AGGAACTGGATCAATATCAACAGAAATTGGTGGATTATCAGGCTGCTGATGCGGTTATCCGCCCGGTTAAGCGGTTGACT
GAGATGTTGCGTAAATATCAGAGTGCGCTGATTTAA

Upstream 100 bases:

>100_bases
ACCACGGCCACGGTGGTGATCACCGGGCCGAATGATCGTGATCCTCATCAGGCATCGCCCATGACCAAGTTGATGCATCG
TCTACGTGAGTTTGGCTAAT

Downstream 100 bases:

>100_bases
CCGATAACCTACGGACATAAGGTGTTCTCATCACCTCATCAAGGGCTATAATAAGTTTGGTACCAGACTGCTGACAAACC
CCGATAATTCGATCTTAAAT

Product: p-hydroxybenzoic acid efflux subunit AaeB

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MTHPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGAIRHRGWLRIIGTFIGCIGGL
VIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFGLAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVM
ADLLFSPRSIKQDIDRLVDKVLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLH
TESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEAIPHTISSWVGAATRYLLLSK
GIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTGIATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRR
MALDFLVGVIIALPIGALYFMFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQF
LDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPALYQQLNQLLMMFPADIDKYRL
ALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVNNDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLT
EMLRKYQSALI

Sequences:

>Translated_651_residues
MTHPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGAIRHRGWLRIIGTFIGCIGGL
VIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFGLAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVM
ADLLFSPRSIKQDIDRLVDKVLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLH
TESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEAIPHTISSWVGAATRYLLLSK
GIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTGIATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRR
MALDFLVGVIIALPIGALYFMFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQF
LDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPALYQQLNQLLMMFPADIDKYRL
ALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVNNDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLT
EMLRKYQSALI
>Mature_650_residues
THPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGAIRHRGWLRIIGTFIGCIGGLV
IIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFGLAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVMA
DLLFSPRSIKQDIDRLVDKVLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLHT
ESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEAIPHTISSWVGAATRYLLLSKG
IQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTGIATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRRM
ALDFLVGVIIALPIGALYFMFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQFL
DSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPALYQQLNQLLMMFPADIDKYRLA
LTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVNNDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLTE
MLRKYQSALI

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=642, Percent_Identity=64.6417445482866, Blast_Score=850, Evalue=0.0,
Organism=Escherichia coli, GI1787933, Length=570, Percent_Identity=22.6315789473684, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 72438; Mature: 72307

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGA
CCCCHHEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHH
IRHRGWLRIIGTFIGCIGGLVIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
LAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVMADLLFSPRSIKQDIDRLVDK
HHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEA
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
IPHTISSWVGAATRYLLLSKGIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
IATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRRMALDFLVGVIIALPIGALYF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCHHHHHHHH
LDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YQQLNQLLMMFPADIDKYRLALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECC
NDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLTEMLRKYQSALI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGA
CCCHHEEHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHH
IRHRGWLRIIGTFIGCIGGLVIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFG
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
LAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVMADLLFSPRSIKQDIDRLVDK
HHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEA
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
IPHTISSWVGAATRYLLLSKGIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
IATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRRMALDFLVGVIIALPIGALYF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQF
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCCHHHHHHHH
LDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YQQLNQLLMMFPADIDKYRLALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECC
NDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLTEMLRKYQSALI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA