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The map label for this gene is mreC [H]

Identifier: 218930677

GI number: 218930677

Start: 4088544

End: 4089539

Strand: Direct

Name: mreC [H]

Synonym: YPO3666

Alternate gene names: 218930677

Gene position: 4088544-4089539 (Clockwise)

Preceding gene: 218930676

Following gene: 218930678

Centisome position: 87.86

GC content: 50.9

Gene sequence:

>996_bases
ATGAAGCCGATTTTTAGTCGGGGTCCATCCCTGCAACTGCGACTCTTCTTTGCCATTATTGCGGCCATTGTACTGGTTAT
TGCTGATAGCCGGTTGGGTACGTTCGTTAAAATACGGACTTACATGGACACCGCAGTTAGCCCTTTCTATTTTCTGGCCA
ATGGGCCACGTAAAATTCTCGACAACGTTTCTGATACGCTAGCCACTCGCGAACAACTGGAGTTGGAGAATCGTGCGTTA
CGCCAAGAGCTGTTACTGAAAAATACCGATCTTCAATTACTGGGGCAGTTTAAACAGGAAAACAACCGCTTACGGGAATT
ATTGGGTTCTCCTCTGCGTCAGGATGAGCAAAAAATGGTGACTCAGGTCATGTCCAGCGGGACAGACCCTTATAGTGATC
ATGTTGTGATTGATAAAGGCTCGAACAGCGGCGTTTATGAGGGCCAACCGGTCATTAGTGATCGCGGTGTCGTCGGCCAG
GTTGTTGCAGTGAGTAAATTTACCAGCCGCGTATTATTGATTTGCGATGCTTCCCATGCACTGCCTATTCAGGTGCTGCG
TAATGATATTCGGGTGATTGCTGCCGGTAGCGGGTGTAGCGATGATTTATTATTGGAGCATTTACCCAGTAATACAGATA
TTCGTGTAGGCGATGTGCTGGTAACGTCGGGCTTGGGTGGGCGCTTCCCTGAAGGCTATCCCGTTGCCGTTGTCTCTTCG
GTCAAAGTCGACAACCAGCGCGCTTATACGGTTATTCAAGCTCGGCCCACCGCAGATTTACAACGCTTACGTTATTTACT
GCTATTGTGGGGCGCTGATCGTAATGGTGATATGCCAATGCCACCGGATGAGGTACGCCGGGTCGCCAATGAACGTCTGG
CACCAATGATGTCTCAGGTGTTGCCTTCTGCTGATGCTATGGGGCCGCCTGCGCCTGCCGCATCTACGCCCGCGGGTGCC
ACACCAGGAGTTGTCACACCAGGAGTTTCGCCGTGA

Upstream 100 bases:

>100_bases
GCGAATGAATAACGCTAACACTGCTGTAATTTCAAGTGACAAGGTATTTTACTTACCCGATTTAGTGTCTCCTCTTGTTG
TCGAGGAATACGCATAATTT

Downstream 100 bases:

>100_bases
ATCGTTACAGTAGTCATGGTCGCTGGGTTATCTGGCTATCCTTCCTGATTGCGATGGTGCTGCAAATTATGCCGTGGCCT
GAACAGATCTATATGTTTCG

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKPIFSRGPSLQLRLFFAIIAAIVLVIADSRLGTFVKIRTYMDTAVSPFYFLANGPRKILDNVSDTLATREQLELENRAL
RQELLLKNTDLQLLGQFKQENNRLRELLGSPLRQDEQKMVTQVMSSGTDPYSDHVVIDKGSNSGVYEGQPVISDRGVVGQ
VVAVSKFTSRVLLICDASHALPIQVLRNDIRVIAAGSGCSDDLLLEHLPSNTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKVDNQRAYTVIQARPTADLQRLRYLLLLWGADRNGDMPMPPDEVRRVANERLAPMMSQVLPSADAMGPPAPAASTPAGA
TPGVVTPGVSP

Sequences:

>Translated_331_residues
MKPIFSRGPSLQLRLFFAIIAAIVLVIADSRLGTFVKIRTYMDTAVSPFYFLANGPRKILDNVSDTLATREQLELENRAL
RQELLLKNTDLQLLGQFKQENNRLRELLGSPLRQDEQKMVTQVMSSGTDPYSDHVVIDKGSNSGVYEGQPVISDRGVVGQ
VVAVSKFTSRVLLICDASHALPIQVLRNDIRVIAAGSGCSDDLLLEHLPSNTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKVDNQRAYTVIQARPTADLQRLRYLLLLWGADRNGDMPMPPDEVRRVANERLAPMMSQVLPSADAMGPPAPAASTPAGA
TPGVVTPGVSP
>Mature_331_residues
MKPIFSRGPSLQLRLFFAIIAAIVLVIADSRLGTFVKIRTYMDTAVSPFYFLANGPRKILDNVSDTLATREQLELENRAL
RQELLLKNTDLQLLGQFKQENNRLRELLGSPLRQDEQKMVTQVMSSGTDPYSDHVVIDKGSNSGVYEGQPVISDRGVVGQ
VVAVSKFTSRVLLICDASHALPIQVLRNDIRVIAAGSGCSDDLLLEHLPSNTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKVDNQRAYTVIQARPTADLQRLRYLLLLWGADRNGDMPMPPDEVRRVANERLAPMMSQVLPSADAMGPPAPAASTPAGA
TPGVVTPGVSP

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=316, Percent_Identity=81.3291139240506, Blast_Score=479, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 35924; Mature: 35924

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFSRGPSLQLRLFFAIIAAIVLVIADSRLGTFVKIRTYMDTAVSPFYFLANGPRKIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCEEEECCCHHHHH
DNVSDTLATREQLELENRALRQELLLKNTDLQLLGQFKQENNRLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TQVMSSGTDPYSDHVVIDKGSNSGVYEGQPVISDRGVVGQVVAVSKFTSRVLLICDASHA
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCC
LPIQVLRNDIRVIAAGSGCSDDLLLEHLPSNTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
CHHHHHHCCEEEEEECCCCCHHHHHHHCCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKVDNQRAYTVIQARPTADLQRLRYLLLLWGADRNGDMPMPPDEVRRVANERLAPMMSQV
EEECCCEEEEEEEECCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSADAMGPPAPAASTPAGATPGVVTPGVSP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPIFSRGPSLQLRLFFAIIAAIVLVIADSRLGTFVKIRTYMDTAVSPFYFLANGPRKIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCEEEECCCHHHHH
DNVSDTLATREQLELENRALRQELLLKNTDLQLLGQFKQENNRLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TQVMSSGTDPYSDHVVIDKGSNSGVYEGQPVISDRGVVGQVVAVSKFTSRVLLICDASHA
HHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCC
LPIQVLRNDIRVIAAGSGCSDDLLLEHLPSNTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
CHHHHHHCCEEEEEECCCCCHHHHHHHCCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKVDNQRAYTVIQARPTADLQRLRYLLLLWGADRNGDMPMPPDEVRRVANERLAPMMSQV
EEECCCEEEEEEEECCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSADAMGPPAPAASTPAGATPGVVTPGVSP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2687239; 9278503; 3049542 [H]