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The map label for this gene is gltB [H]

Identifier: 218930569

GI number: 218930569

Start: 3967134

End: 3971600

Strand: Direct

Name: gltB [H]

Synonym: YPO3557

Alternate gene names: 218930569

Gene position: 3967134-3971600 (Clockwise)

Preceding gene: 218930563

Following gene: 218930570

Centisome position: 85.25

GC content: 52.47

Gene sequence:

>4467_bases
ATGTTGTATGATCAATCCCAAGAGAGGGACAACTGTGGTTTCGGCCTAATCGCCCATATAGAAGGCGAACCTAGCCATAA
GGTAGTGCGCACCGCAATACACGCACTGGCCCGTATGCAACACCGTGGCGCGATCCTTGCTGATGGCAAGACGGGCGATG
GTTGTGGCTTATTATTGCAAAAACCGGATCACTTTTTCCGGATGGTCGCTGAAGAACGCGGGTGGCGTTTGGCCAAAAAC
TATGCCGTAGGTATGATGTTTCTCAGTCAGGACGAAGAACTCGCCAAGGCAAGCCGCCGCATTGTAGAAGAAGAATTGCA
AAATGAAACGCTGTCGATTGTCGGCTGGCGTGAAGTGCCGACGAACCCAGATGTACTCGGTGAAATCGCTCTCTCCTCCC
TGCCCCGGATTGAACAAATTTTTGTGAACGCCCCTGCGGGCTGGCGTTCGCGTGATATGGAACGTCGCCTGTTTGTGGCA
CGCCGCCGTATTGAAAAGCGTATTTCAGATAAAGATTTCTACGCATGTAGCTTCTCGAATCTGGTGACAATCTATAAAGG
CTTATGTATGCCTGCGGATTTGCCACGCTTTTATCTTGATTTGGCTGACCTGCGCCTCGAATCGGCAATCTGTCTGTTCC
ATCAACGCTTCTCAACCAATACCGTCCCCCGCTGGCCGCTGGCTCAGCCGTTCCGCTATCTGGCACATAACGGCGAAATC
AACACCATCGCCGGTAACCGCCAATGGGCCAAGGCGCGTGCCTATAAATTTAAAACGCCATTAATTCCGGATTTACAGGA
TGCGGCCCCCTTCGTCAATGAGACCGGCTCTGACTCCAGTTCGCTGGATAACATGTTGGAACTGTTCCTCAGTGGCGGGA
TGGACTTGATCCGTGCAATGCGTCTGTTAGTGCCACCGGCCTGGCAGAACAACCCAGATATGGATACTGATCTGCGTGCC
TTCTTTGACTTCAACTCCATGCATATGGAACCGTGGGATGGCCCCGCTGGGATCGTGATGTCTGATGGTCGCTACGCGGC
CTGTAACCTTGACCGTAATGGCCTGCGCCCTGCGCGCTATGTCATCACCAAAGACAAACTGATTACCTGTGCCTCGGAAG
TCGGGATTTGGGATTACCAGCCCGATGAAGTGGTTGAAAAAGGCCGCGTGGGTCCTGGCGAACTCATGGTGATTGATACC
CGCAGCGGTAAAATCTTGCATTCCGCCGAAACAGACAACGATCTAAAAAGCCGCCACCCGTATAAAGAGTGGATGGAGAA
GAACGTTAAGCGTCTGGTGCCATTCGAAGACCTACCGGAAGAGCAGGTAGGGAGCCGTCAGTTAGATGATTCGCAGTTGG
AAACTTATCAGAAGCAGTTTGGTTACAGCAACGAAGAGCTGGATCAAATCATTCGCGTGCTGGGTGAAAACGGTCAGGAA
GCCACCGGGTCGATGGGCGATGACACGCCATTTGCCGTGCTCTCCAGCGGCCCGCGCATTATTTATGACTATTTCCGCCA
GCAATTTGCTCAGGTGACTAACCCCCCTATCGATCCACTGCGTGAAGCACACGTTATGTCACTGGCGACCAGTATTGGCC
GTGAGATGAACGTCTTCTGCGAAGCTGAGGGCCAGGCTCACCGCTTGAGCTTTAAATCGCCGATCTTGCTTTACTCTGAT
TTTCAGCAATTAACCACGCTGGAAGGGGAACATTACCGCGCTGACCGTTTAGATCTGACGTTCAATCCCGCAGAGAATGA
CTTGGAGCAAGCTGTACTGTCGCTGTGTGATGAAGCAGAGCGTAAAGTTCGTGATGGTGCCGTTATGTTGGTGCTATCAG
ACCGTGCCATTGCGCCTAACCGCTTGCCGGTGCCAGCCCCCATGGCTGTCGGTGCAATTCAAACGCGTTTGGTGGACAAA
AGCCTACGCTGTGACGCGAATATTATTGTCGAAACCGCCAGCGCACGTGATCCACACCACTTCGCGGTGCTGCTCGGTTT
TGGTGCGACAGCGATATACCCTTATCTGGCTTATGAGTCATTGGCCAAACTGGTTGATTCCCAAGCGATTGATAAAAAGT
ATCGCGATGTGATGCTCAATTATCGCAACGGTATCAATAAAGGGCTGTACAAGATCATGTCCAAAATGGGCATCTCGACG
GTGGCCTCTTACCGCTGTGCCAAGCTGTTTGAAGCGGTTGGTTTGCATCGTGATTTGTCTGATCTCTGTTTCCAGGGTGT
TGTCAGCCGTATCGGCGGGGCCAGCTTCAGTGATTTCCAACAGGATTTACAGAATCTGTCCAAACGCGCCTGGCTGAAAC
GTAAGCCTCTGGATCAAGGCGGCTTGCTGAAATTTGTCCACAACGGCGAATACCACGCCTACAACCCAGATGTGGTCAGT
ACCTTACAAAAAGCCGTTCATAGCGGTGAATACAGCGATTATCAGGCGTACGCCAAGCTGGTTAATGAGCGCCCGATTGC
CACACTGCGCGATCTGTTAGCCATTAAACCGCAAGGCACTCCGATTCCGGTGGATCAAGTTGAACCGGCTGAATCTCTGT
TTAAACGTTTTGATACTGCTGCAATGTCTATCGGTGCCTTAAGCCCGGAAGCCCATGAATCACTGGCTATCGCCATGAAC
AGCTTGGGAGGTTTCTCTAATTCCGGCGAAGGGGGCGAAGATCCGGCCCGTTACGGCACCAATAAGGTGTCCCGTATCAA
GCAGGTGGCCTCTGGTCGTTTCGGTGTAACACCGGCATATTTGGTCAATGCGGATGTTATCCAGATTAAAGTGGCTCAAG
GAGCGAAACCCGGTGAAGGCGGCCAGTTACCGGGTGATAAAGTCACGCCGTATATCGCCAAACTGCGCTATTCCGTACCG
GGTGTGACCTTGATATCCCCGCCACCGCATCATGATATTTATTCAATCGAAGACTTGGCCCAGCTAATTTTCGATTTGAA
GCAGGTCAATCCGAAAGCCATGATTTCGGTGAAACTGGTCTCTGAACCGGGTGTCGGCACCATTGCGACCGGTGTCGCCA
AAGCTTACGCCGATTTAATTACTATTGCCGGTTACGATGGGGGGACCGGTGCCAGCCCGCTGTCTTCGGTGAAATATGCC
GGTTGCCCATGGGAACTGGGTCTGGTTGAAACACAACAAGCATTGGTGGCCAACGGCTTACGCCATAAGATCCGCCTGCA
AGTTGATGGCGGCCTGAAAACTGGCGTTGATATTGTTAAAGCCGCTATTTTGGGGGCGGAAAGCTTCGGTTTTGGTACCG
GCCCTATGGTGGCACTAGGGTGTAAATACTTACGCATTTGCCACCTGAATAACTGCGCGACCGGTGTGGCTACGCAAGAT
GAAAAATTGCGTCGTGACCATTATCACGGCTTACCGGAACGCGTAGTGAACTACTTCCACTTCATCGCCCGTGAAACCCG
TGAAACCCGTGAAATCATGGCCGAACTGGGCGTGAGTCAACTGGTTGATTTAATTGGCCGAACCGATATGTTGCTGGAAC
TGGATGGCATCTCAGCGAAGCAAAACAAACTGGATCTGTCGCCAATGCTGAAAACAGCAACGCCACATCCGGGCAAGGCG
CTGTATTGTACTGAAAGTAACCCGCCGTTCGATAAAGGCTTACTGAACAAAGAGTTGCTGTCTCAAGCTGAACCCTATAT
TGAAGCCAAACAAAGTAAGACGTTCTATTTTGATATTCGCAACACTGACCGCTCCGTCGGCGCAGCATTGTCGGGGGCGA
TTGCCACGAAACATGGCGATCAAGGGCTGGCAACTGATCCGATCAAAGCGTATTTCTCCGGGACTGCCGGTCAGAGTTTT
GGGGTGTGGAATGCCGGTGGCGTTGAGTTGATGCTGACTGGCGACGCGAATGACTACGTCGGTAAAGGGATGGCCGGTGG
CCGTATCGCGGTACGTCCGCCAGTCGGTTCCAACTTCCGCAGCCATGAAGCGAGCATCATTGGGAACACCTGCCTATACG
GTGCCACCGGCGGTAAATTGTTCGCCGCAGGCCGGGCGGGTGAACGCTTCGCGGTGCGTAACTCCGGGGCGATCACCGTC
GTTGAAGGTATCGGTGATAACGGCTGTGAATATATGACTGGCGGGATTGTCTGTGTTCTGGGCCGTACTGGGATTAACTT
TGGTGCCGGTATGACCGGTGGCTTCGCTTATGTTCTCGATGAAGACGGTGAATTCCGTAAACGTGTTAACCCTGAACTGG
TAGAAGTGCTGGATGTCGAGCAATTGGCTATCCATGAAGAACATCTGCGCGGGCTGATCACTGAACATGTTCAGTTGACT
GGCTCTAGCCGTGGCGAAGAGATTCTGGCTAACTGGCCAGAATGGGTGACCAAGTTTGCCTTGGTTAAACCGAAATCCAG
CGATGTGAAAGCACTGTTGGGCCACCGTAGCCGTTCCGCAGCTGAGCTGCGGGTTCAAGCGCAGTAA

Upstream 100 bases:

>100_bases
CCGCAAAGCACGCGTCTGTCAGCCCACACTGTCTGATATCAATATGTCCTTTACGAGCTGGTTTGTGAGAGTCTCACAGA
GCCTGGGGAGGTTCACTGAT

Downstream 100 bases:

>100_bases
GGAGTTGATATGAGTCAGAACGTTTATCAGTTTATCGACTTACAGCGCGTCGATCCGCCTAAAAAACCGCTGAAGATCCG
TAAAATTGAATTTGTTGAAA

Product: glutamate synthase subunit alpha

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1488; Mature: 1488

Protein sequence:

>1488_residues
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDHFFRMVAEERGWRLAKN
YAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVA
RRRIEKRISDKDFYACSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGKILHSAETDNDLKSRHPYKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQE
ATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAERKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDK
SLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGIST
VASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQGGLLKFVHNGEYHAYNPDVVS
TLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFHFIARETRETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKA
LYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGDQGLATDPIKAYFSGTAGQSF
GVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITV
VEGIGDNGCEYMTGGIVCVLGRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLT
GSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ

Sequences:

>Translated_1488_residues
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDHFFRMVAEERGWRLAKN
YAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVA
RRRIEKRISDKDFYACSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGKILHSAETDNDLKSRHPYKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQE
ATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAERKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDK
SLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGIST
VASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQGGLLKFVHNGEYHAYNPDVVS
TLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFHFIARETRETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKA
LYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGDQGLATDPIKAYFSGTAGQSF
GVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITV
VEGIGDNGCEYMTGGIVCVLGRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLT
GSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
>Mature_1488_residues
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDHFFRMVAEERGWRLAKN
YAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVA
RRRIEKRISDKDFYACSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGKILHSAETDNDLKSRHPYKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQE
ATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAERKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDK
SLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGIST
VASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQGGLLKFVHNGEYHAYNPDVVS
TLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFHFIARETRETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKA
LYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGDQGLATDPIKAYFSGTAGQSF
GVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITV
VEGIGDNGCEYMTGGIVCVLGRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLT
GSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1489, Percent_Identity=87.5083948959033, Blast_Score=2702, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1531, Percent_Identity=41.9986936642717, Blast_Score=1088, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1535, Percent_Identity=42.3452768729642, Blast_Score=1149, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1500, Percent_Identity=43.4666666666667, Blast_Score=1143, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1500, Percent_Identity=43.4666666666667, Blast_Score=1143, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=372, Percent_Identity=44.8924731182796, Blast_Score=291, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24665543, Length=372, Percent_Identity=44.8924731182796, Blast_Score=291, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 163682; Mature: 163682

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDHFFRMVAEERGWRLAKNYAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVP
CCHHHHHHHHHHCCCEEEHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVARRRIEKRISDKDFYACSFSN
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHH
LVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCE
NTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAM
EEEECCCHHHHHHHEEECCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
RLLVPPAWQNNPDMDTDLRAFFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARY
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCE
VITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGKILHSAETDNDLKSRHP
EEECCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCHHHHCCC
YKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQE
HHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
ATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFC
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EAEGQAHRLSFKSPILLYSDFQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAE
ECCCCEEEEECCCCEEEEHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHH
RKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDKSLRCDANIIVETASARDPHH
HHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCE
FAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGIST
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
VASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GLLKFVHNGEYHAYNPDVVSTLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
PIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMNSLGGFSNSGEGGEDPARYGT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
NKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
HHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEECCC
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLI
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVK
EEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
AAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRRDHYHGLPERVVNYFH
HHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
FIARETRETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKA
HHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCE
LYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGD
EEECCCCCCHHHHHCCHHHHHHCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHEECCCC
QGLATDPIKAYFSGTAGQSFGVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFR
CCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCEEEECCCCCCCCC
SHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVEGIGDNGCEYMTGGIVCVL
CCCHHEECCEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCEEEEE
GRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLT
ECCCCCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
CCCCCCHHHHCCHHHHHHHHEECCCCCCHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MLYDQSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDHFFRMVAEERGWRLAKNYAVGMMFLSQDEELAKASRRIVEEELQNETLSIVGWREVP
CCHHHHHHHHHHCCCEEEHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TNPDVLGEIALSSLPRIEQIFVNAPAGWRSRDMERRLFVARRRIEKRISDKDFYACSFSN
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHH
LVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCE
NTIAGNRQWAKARAYKFKTPLIPDLQDAAPFVNETGSDSSSLDNMLELFLSGGMDLIRAM
EEEECCCHHHHHHHEEECCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
RLLVPPAWQNNPDMDTDLRAFFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARY
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCE
VITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGKILHSAETDNDLKSRHP
EEECCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCHHHHCCC
YKEWMEKNVKRLVPFEDLPEEQVGSRQLDDSQLETYQKQFGYSNEELDQIIRVLGENGQE
HHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
ATGSMGDDTPFAVLSSGPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFC
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EAEGQAHRLSFKSPILLYSDFQQLTTLEGEHYRADRLDLTFNPAENDLEQAVLSLCDEAE
ECCCCEEEEECCCCEEEEHHHHHHHHCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHH
RKVRDGAVMLVLSDRAIAPNRLPVPAPMAVGAIQTRLVDKSLRCDANIIVETASARDPHH
HHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCE
FAVLLGFGATAIYPYLAYESLAKLVDSQAIDKKYRDVMLNYRNGINKGLYKIMSKMGIST
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
VASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDFQQDLQNLSKRAWLKRKPLDQG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GLLKFVHNGEYHAYNPDVVSTLQKAVHSGEYSDYQAYAKLVNERPIATLRDLLAIKPQGT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
PIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMNSLGGFSNSGEGGEDPARYGT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
NKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
HHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEECCC
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLI
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVK
EEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
AAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRRDHYHGLPERVVNYFH
HHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
FIARETRETREIMAELGVSQLVDLIGRTDMLLELDGISAKQNKLDLSPMLKTATPHPGKA
HHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCE
LYCTESNPPFDKGLLNKELLSQAEPYIEAKQSKTFYFDIRNTDRSVGAALSGAIATKHGD
EEECCCCCCHHHHHCCHHHHHHCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHEECCCC
QGLATDPIKAYFSGTAGQSFGVWNAGGVELMLTGDANDYVGKGMAGGRIAVRPPVGSNFR
CCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCEEEECCCCCCCCC
SHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVEGIGDNGCEYMTGGIVCVL
CCCHHEECCEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCEEEEE
GRTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQLT
ECCCCCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
GSSRGEEILANWPEWVTKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
CCCCCCHHHHCCHHHHHHHHEECCCCCCHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 1673677; 2643092 [H]