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The map label for this gene is pheC [H]

Identifier: 218930361

GI number: 218930361

Start: 3730412

End: 3731182

Strand: Direct

Name: pheC [H]

Synonym: YPO3343

Alternate gene names: 218930361

Gene position: 3730412-3731182 (Clockwise)

Preceding gene: 218930360

Following gene: 218930362

Centisome position: 80.16

GC content: 43.32

Gene sequence:

>771_bases
ATGCAGATGAAAAAATTATCTTTGGGAATAATGGTATTGGCATTAATCAGTAGCCAACACGTATTAGCAAAAAATTGGCA
GGAAATTAAGCAAAGTGGTGAGCTGCGTATTGGGGTGCCAGGTGACTATGCGCCTTTAGCTTTCCATGATAAACAGGGCC
AATTGATCGGCTACGATGTTGATATGGCAAACGCCTTTGGTGAAGACCTTAAATTGAAGGTTAATTTTGTTTCGACCAGT
TGGCCAACTCTTTCAGACGATTTGGCGGCAGATAAATTTGATATTGCCATGGGGGGCGTCACAGCAACGCCCGGCAGAGA
AGCGCAATTTGCTTTATCCCACGCCGTCGTGAAAAATGGGAAAATTGCGCTGACCCATTGCCAGAAAGTCAATAAATTCC
CCACGCTTGATGCGATTGATCGTCAAAACGTCAAAGTTATTGTCAACCCTGGCGGTACCAACCAATCGTTTGTTGATGCA
AATATTAAGCAAGCGCAAATCATCCGAACCAAAGATAACGTTGCTAACCTGCAAGGTATACGTAATAAAAGTGCAGATAT
TATGTTCACTGACTTAATCGAAGGCGATTATTATCAGAGCAAAGAACCTGGCGTATTTTGTGTCGCCACCCCAGAGGTTT
TAGCCGGAACGGGCAGCTACAAAGTTTATATGATGGCTAAGGATAATCAGCCGTTGTTAGAAGAAGTTAACCAGTGGCTG
GCCGGGAAGACCAAAACCTTATTAGCACAAAAGTGGAATATTTCTGAGTAG

Upstream 100 bases:

>100_bases
GAAAGTTTGACCGGGGAATATATTCCTCATTCCTGAGCAATATACAGTAGGATAATTTACCCTGATTGACCTTAATGGGC
TCTTATAAAAAATAACAGGA

Downstream 100 bases:

>100_bases
CCAGTAAGAGGCGATGGCCGTTTATTACAGCACTCTTCGCTTAGTAAACGGTCTGCCCGATATCATCTTCAATAGTCACC
ACAAAAAAACAGAAAAATAC

Product: putative extracellular solute-binding protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQMKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANAFGEDLKLKVNFVSTS
WPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDA
NIKQAQIIRTKDNVANLQGIRNKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWL
AGKTKTLLAQKWNISE

Sequences:

>Translated_256_residues
MQMKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANAFGEDLKLKVNFVSTS
WPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDA
NIKQAQIIRTKDNVANLQGIRNKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWL
AGKTKTLLAQKWNISE
>Mature_256_residues
MQMKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANAFGEDLKLKVNFVSTS
WPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDA
NIKQAQIIRTKDNVANLQGIRNKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWL
AGKTKTLLAQKWNISE

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=255, Percent_Identity=24.7058823529412, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28116; Mature: 28116

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCEEEEEC
DMANAFGEDLKLKVNFVSTSWPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNG
HHHHHCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHCCC
KIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANIKQAQIIRTKDNVANLQGI
CEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCEEEEEECCCCHHHHHHC
RNKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWL
CCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCHHHHHHHHHH
AGKTKTLLAQKWNISE
CCCHHEEEEECCCCCC
>Mature Secondary Structure
MQMKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDV
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCEEEEEC
DMANAFGEDLKLKVNFVSTSWPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNG
HHHHHCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHCCC
KIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANIKQAQIIRTKDNVANLQGI
CEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCEEEEEECCCCHHHHHHC
RNKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWL
CCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCHHHHHHHHHH
AGKTKTLLAQKWNISE
CCCHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]