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The map label for this gene is dmsA [H]

Identifier: 218930014

GI number: 218930014

Start: 3312842

End: 3315268

Strand: Direct

Name: dmsA [H]

Synonym: YPO2965

Alternate gene names: 218930014

Gene position: 3312842-3315268 (Clockwise)

Preceding gene: 218930012

Following gene: 218930015

Centisome position: 71.19

GC content: 47.26

Gene sequence:

>2427_bases
ATGAATAACAATAAAACACCGCTCACCGGCTCACTGAGTCGTCGTGAATTTATTCAAACATCCGCCGTAGTGACCGGGGC
TGCGGCAATTGCCGGTTCAATCGCCCTCCCATTCTCCGTCCATGCTGCGGCTTCAGAACATGCCCCCACGGCGGCTGAAG
AGAGCATTAAATACAGTGCTTGCCTGGTTAACTGTGGCAGCCGCTGCCCGCTAAAAGTTCATGTTAAAAACGGTGAAATA
ATTAAAATTGCTAATGAAGCCATTTATGATGATTCCACCTTTGGCTTACACCAAATTCGCCCCTGCTTACGTGGCCGTTC
AGTACGATGGAAAACCTATAATCCGGATCGGGTTAAATATCCAATGTTACGAGTGGGTAAACGCGGTGAAGGTAAATTCA
AGCGTATCAGTTGGGATGAAGCCACAACTATCGTTGCGGATAATCTGAAAAAAACGATTGTTCAATACGGCAACGAAGCA
ATTTATTATCAATATGGCACTGGTTCAACAGGGGCTAATTTACAAGGCCGCAATGCCTGTAAACGTATGTTGAGTTTGAT
CGGCGGTTATCTTGATCAGCACGGTACTTATTCTACCGCCCAAATCAATACTGTCATGCCTTATGTCTACGGCAACTTAG
ATGAAACGCTGCTGGACGAAATTAAAAATTCTGATCTGGTGGTGATGTTTGGTCACAATCTGGCAGAAACACGGATGTCA
GGCGGTGGGCAATATATTGAAACGGTTCAGGCGTTGGGTCAAAGCCGAGCCAAAGTCATTATTATTGACCCACGCATGAC
CGACAGTGTGACCACCCTTAACGCCGAATGGATCCCGATATTCCCAGGGACCGATGCGGCACTGGTCGCCGCGCTGGGGC
ATGTTTTAATTAAAGAGAATCTGACTGACGAACGTTTCCTGCAACAATATTGTGTCGGTTGGGATGCCACCACATTGCCC
TCATCGGCCCCAGCTAACGGATCGTATAAAGATTATATTTTAGGTCTGGGTGCTGACGAAACCGAAAAAACACCAGAATG
GGCCAGTGAGATCACCGGTATTTCACCAACACGTATTATTCAATTAGCCAGAGAACTGGGTAATGCCCGCGCAGCCTGGA
TTTCACAGGGTTGGGGAATTCAACGCACAGCGAACGGGGAGCAAGCGTCCCGCTCGATTATGATGCTCCCATTAATGACC
GGTAACATTGGCCGCGCCGGAACCAATACCGGTGCCTGGGGTGGCAACGTAAAATACCCGGTTCCTGGGTTCAGCATTCC
CAATCCAGTCAAAACGGCCATTCCTTGCTTTATGTGGACCGATGCTATTTTCCGCGGCACTGAAATGACCGCTAAAAATG
CCCATGTGAAAAATAAAGAAAAACTGGATACCAATATTAAGTTTCTCTGGAACTACGCCAGTAACGTTATAGCAAATCAG
CACTCTGATCTGAATAAAACCAATACTATTTTGCAAGATGAGTCATTGTGCGAATTTATTTTGGTCTGGGAAAACCATAT
GACCAATTCGGCGAAGTACGCAGATTTATTATTACCAGACGTCACGTCGGTTGAATCAAATGACCTGATTGATAACTCCT
ATGCCAGTGGTGCTTATCACTATGTCACCCGGATGCAAAATACCATTGAGCCGCTGTGGGAATGCCGCCCCTCATACGAT
GTATTAGCCGAGATCGCCACTAAATTAGGCGTGGGGGATGCCTTTACTGAAGGACATACCCAGCAAGAATGGATTGAAAT
CAGCTATAACAAAATGCGTGATAATAATCCGGCGCTGCCGCCTTTCAGTGATACCCATAACAAAGGCATTATTGACCGTA
TTTTTGCTGACAGTAGCCAATATATCGCGTTAAAAGATTTCCGCGATGACCCATTAAATAACCCGTTAAAAACCCCATCA
GGCAAGATTGAGATCTATTCAGAAGCACTGGCAACACTCGCACACGAGTGGCAGTTGACACCGGGTGACCGCATTACCGC
GGTAGCTGAATATTGTCCGACCCCTGAGGGTGTCAGTGATCAAGAAACCCTAAAGAGCTACCCTCTACAAATGACCGGTT
TCCATGTTAAAGGCCATACCCACTCAACCTATTACAATGTCGCGATGCTGCGCGAAGCGGTACCTCATCAATTCTGGATG
AACCCGATTGATGCACAGGCGCGTGGCATACAGCAAGGCGAGCGGGTCGAAATATTTAATAGCCGTGGCCGTATCCATAT
TGCGGTCAAAATTACTGAGCGGGTATTACCGGGGGTTATTGCTGTGCCACAAGGGGCATGGCGTAATCTCAACAAGGACG
GTATCGACGTGGGTGGCTGTATCAATACGTTGACGACACAACGCCCTTCGCCATTAGCGAAAGGTAATCCTCAACACACC
AACCTCGTTGAAGTAAAACGTGCATAA

Upstream 100 bases:

>100_bases
CCAGTTCTATACCCAAGTCATTGGCATTGTTGCTAACACCACGACAACGTCAAGTAAAAAAGGGATGTCCTGCTCTTTTA
TTTCCGCAAGGATAATGTTG

Downstream 100 bases:

>100_bases
GGAGCTGAATAATGAAGCAATATGGTTTTTTTGTTGACTCCACCAAGTGCACGGGGTGTAAAACCTGCCAAGTCAGTTGT
AAGGACGAAAAGAATCTGGA

Product: putative dimethyl sulfoxide reductase chain A protein

Products: NA

Alternate protein names: DMSO reductase [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MNNNKTPLTGSLSRREFIQTSAVVTGAAAIAGSIALPFSVHAAASEHAPTAAEESIKYSACLVNCGSRCPLKVHVKNGEI
IKIANEAIYDDSTFGLHQIRPCLRGRSVRWKTYNPDRVKYPMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEA
IYYQYGTGSTGANLQGRNACKRMLSLIGGYLDQHGTYSTAQINTVMPYVYGNLDETLLDEIKNSDLVVMFGHNLAETRMS
GGGQYIETVQALGQSRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKENLTDERFLQQYCVGWDATTLP
SSAPANGSYKDYILGLGADETEKTPEWASEITGISPTRIIQLARELGNARAAWISQGWGIQRTANGEQASRSIMMLPLMT
GNIGRAGTNTGAWGGNVKYPVPGFSIPNPVKTAIPCFMWTDAIFRGTEMTAKNAHVKNKEKLDTNIKFLWNYASNVIANQ
HSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDNSYASGAYHYVTRMQNTIEPLWECRPSYD
VLAEIATKLGVGDAFTEGHTQQEWIEISYNKMRDNNPALPPFSDTHNKGIIDRIFADSSQYIALKDFRDDPLNNPLKTPS
GKIEIYSEALATLAHEWQLTPGDRITAVAEYCPTPEGVSDQETLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWM
NPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPGVIAVPQGAWRNLNKDGIDVGGCINTLTTQRPSPLAKGNPQHT
NLVEVKRA

Sequences:

>Translated_808_residues
MNNNKTPLTGSLSRREFIQTSAVVTGAAAIAGSIALPFSVHAAASEHAPTAAEESIKYSACLVNCGSRCPLKVHVKNGEI
IKIANEAIYDDSTFGLHQIRPCLRGRSVRWKTYNPDRVKYPMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEA
IYYQYGTGSTGANLQGRNACKRMLSLIGGYLDQHGTYSTAQINTVMPYVYGNLDETLLDEIKNSDLVVMFGHNLAETRMS
GGGQYIETVQALGQSRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKENLTDERFLQQYCVGWDATTLP
SSAPANGSYKDYILGLGADETEKTPEWASEITGISPTRIIQLARELGNARAAWISQGWGIQRTANGEQASRSIMMLPLMT
GNIGRAGTNTGAWGGNVKYPVPGFSIPNPVKTAIPCFMWTDAIFRGTEMTAKNAHVKNKEKLDTNIKFLWNYASNVIANQ
HSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDNSYASGAYHYVTRMQNTIEPLWECRPSYD
VLAEIATKLGVGDAFTEGHTQQEWIEISYNKMRDNNPALPPFSDTHNKGIIDRIFADSSQYIALKDFRDDPLNNPLKTPS
GKIEIYSEALATLAHEWQLTPGDRITAVAEYCPTPEGVSDQETLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWM
NPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPGVIAVPQGAWRNLNKDGIDVGGCINTLTTQRPSPLAKGNPQHT
NLVEVKRA
>Mature_808_residues
MNNNKTPLTGSLSRREFIQTSAVVTGAAAIAGSIALPFSVHAAASEHAPTAAEESIKYSACLVNCGSRCPLKVHVKNGEI
IKIANEAIYDDSTFGLHQIRPCLRGRSVRWKTYNPDRVKYPMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEA
IYYQYGTGSTGANLQGRNACKRMLSLIGGYLDQHGTYSTAQINTVMPYVYGNLDETLLDEIKNSDLVVMFGHNLAETRMS
GGGQYIETVQALGQSRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKENLTDERFLQQYCVGWDATTLP
SSAPANGSYKDYILGLGADETEKTPEWASEITGISPTRIIQLARELGNARAAWISQGWGIQRTANGEQASRSIMMLPLMT
GNIGRAGTNTGAWGGNVKYPVPGFSIPNPVKTAIPCFMWTDAIFRGTEMTAKNAHVKNKEKLDTNIKFLWNYASNVIANQ
HSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDNSYASGAYHYVTRMQNTIEPLWECRPSYD
VLAEIATKLGVGDAFTEGHTQQEWIEISYNKMRDNNPALPPFSDTHNKGIIDRIFADSSQYIALKDFRDDPLNNPLKTPS
GKIEIYSEALATLAHEWQLTPGDRITAVAEYCPTPEGVSDQETLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWM
NPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPGVIAVPQGAWRNLNKDGIDVGGCINTLTTQRPSPLAKGNPQHT
NLVEVKRA

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=805, Percent_Identity=52.2981366459627, Blast_Score=827, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=810, Percent_Identity=51.2345679012346, Blast_Score=809, Evalue=0.0,
Organism=Escherichia coli, GI171474008, Length=806, Percent_Identity=49.8759305210918, Blast_Score=781, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=757, Percent_Identity=30.779392338177, Blast_Score=276, Evalue=4e-75,
Organism=Escherichia coli, GI87081994, Length=864, Percent_Identity=28.7037037037037, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1787231, Length=757, Percent_Identity=27.2126816380449, Blast_Score=251, Evalue=2e-67,
Organism=Escherichia coli, GI3868721, Length=781, Percent_Identity=24.1997439180538, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788534, Length=425, Percent_Identity=23.7647058823529, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011888
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 89247; Mature: 89247

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNKTPLTGSLSRREFIQTSAVVTGAAAIAGSIALPFSVHAAASEHAPTAAEESIKYSA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCEEEECCCCCCCCCHHHHHCEEEE
CLVNCGSRCPLKVHVKNGEIIKIANEAIYDDSTFGLHQIRPCLRGRSVRWKTYNPDRVKY
EEEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEC
PMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEAIYYQYGTGSTGANLQGRNAC
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
KRMLSLIGGYLDQHGTYSTAQINTVMPYVYGNLDETLLDEIKNSDLVVMFGHNLAETRMS
HHHHHHHHHHHHCCCCCCEEEEEEECCHHCCCCCHHHHHHHCCCCEEEEECCCHHHHHHC
GGGQYIETVQALGQSRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKEN
CCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHCC
LTDERFLQQYCVGWDATTLPSSAPANGSYKDYILGLGADETEKTPEWASEITGISPTRII
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHH
QLARELGNARAAWISQGWGIQRTANGEQASRSIMMLPLMTGNIGRAGTNTGAWGGNVKYP
HHHHHHCCCCEEHHHCCCCCEECCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
VPGFSIPNPVKTAIPCFMWTDAIFRGTEMTAKNAHVKNKEKLDTNIKFLWNYASNVIANQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEHHHHHHHHCC
HSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDNSYASGAYH
CCCCCHHHCEECCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHH
YVTRMQNTIEPLWECRPSYDVLAEIATKLGVGDAFTEGHTQQEWIEISYNKMRDNNPALP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCHHEEEEHHHCCCCCCCCC
PFSDTHNKGIIDRIFADSSQYIALKDFRDDPLNNPLKTPSGKIEIYSEALATLAHEWQLT
CCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHEECC
PGDRITAVAEYCPTPEGVSDQETLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWM
CCCCHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCHHHCC
NPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPGVIAVPQGAWRNLNKDGIDVGGC
CCCCHHHHCCCCCCEEEEECCCCEEEEEEEEECHHCCCEEECCCHHHHCCCCCCCCCCHH
INTLTTQRPSPLAKGNPQHTNLVEVKRA
HHHHHCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MNNNKTPLTGSLSRREFIQTSAVVTGAAAIAGSIALPFSVHAAASEHAPTAAEESIKYSA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEECCEEEECCCCCCCCCHHHHHCEEEE
CLVNCGSRCPLKVHVKNGEIIKIANEAIYDDSTFGLHQIRPCLRGRSVRWKTYNPDRVKY
EEEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCEEC
PMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEAIYYQYGTGSTGANLQGRNAC
HHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
KRMLSLIGGYLDQHGTYSTAQINTVMPYVYGNLDETLLDEIKNSDLVVMFGHNLAETRMS
HHHHHHHHHHHHCCCCCCEEEEEEECCHHCCCCCHHHHHHHCCCCEEEEECCCHHHHHHC
GGGQYIETVQALGQSRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKEN
CCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHCC
LTDERFLQQYCVGWDATTLPSSAPANGSYKDYILGLGADETEKTPEWASEITGISPTRII
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCHHHHH
QLARELGNARAAWISQGWGIQRTANGEQASRSIMMLPLMTGNIGRAGTNTGAWGGNVKYP
HHHHHHCCCCEEHHHCCCCCEECCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
VPGFSIPNPVKTAIPCFMWTDAIFRGTEMTAKNAHVKNKEKLDTNIKFLWNYASNVIANQ
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEHHHHHHHHCC
HSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDNSYASGAYH
CCCCCHHHCEECCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHH
YVTRMQNTIEPLWECRPSYDVLAEIATKLGVGDAFTEGHTQQEWIEISYNKMRDNNPALP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCHHEEEEHHHCCCCCCCCC
PFSDTHNKGIIDRIFADSSQYIALKDFRDDPLNNPLKTPSGKIEIYSEALATLAHEWQLT
CCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHEECC
PGDRITAVAEYCPTPEGVSDQETLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWM
CCCCHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCHHHCC
NPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPGVIAVPQGAWRNLNKDGIDVGGC
CCCCHHHHCCCCCCEEEEECCCCEEEEEEEEECHHCCCEEECCCHHHHCCCCCCCCCCHH
INTLTTQRPSPLAKGNPQHTNLVEVKRA
HHHHHCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]