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The map label for this gene is clpB5 [H]

Identifier: 218929997

GI number: 218929997

Start: 3289145

End: 3291820

Strand: Reverse

Name: clpB5 [H]

Synonym: YPO2946

Alternate gene names: 218929997

Gene position: 3291820-3289145 (Counterclockwise)

Preceding gene: 218930006

Following gene: 218929996

Centisome position: 70.74

GC content: 47.94

Gene sequence:

>2676_bases
GTGGCTATTACAAGGAAACATCTCTTCGGCAAGCTGGACGCCACTCTTTTCAAAGGTATTGAAAGCGCAACAACGATTTG
TAAATTACGCGGCAATCCTTACGTAGAGTTAGTTCACTGGTTGAATCAGCTTTGGCATCAGGAAGATAACGACCTTAAGC
AGATTATTCGGTATTTTGCGGTGGATGTGGATGCCTTTGAGCGTGAACTGGCTCAGGCACTTGCGAAGTTACCTGTTGGG
GCAACTAGCATTTCAGATTTTTCGTATCATATTGAGTTGGCCACGGAACGGGCTTGGATCTATGCCAGCCTGGAGTGTTT
AGATACCCGTATCCGCAGCGGACATCTGCTGCTTGCGCTATTAACCACAATGGAACTGCGGAGAGCTTTCTTTGCGATTG
CGCCAAGCATGGAAAAAATTCCATTAGAGCATTTAAGCAAAGATTTGAACTTCATTACGCAGGCATCACCAGAAGCGAAT
GAAGCCGCCAGTGATGGCAGCCCGTTGTACGATGGTGCTTTACCTGGCGAAGCCAGTAATGCCATTGGTGCAGCCAAAAG
TGGTGGCGCACTGGCTCAATACACCACAGACCTCACGGCATTAGCACGTGAAGGCAAGATAGATCCGGTATTGGGACGTA
ATCACGAAATCAACACAATGGTTGATATTCTCTTGCGCCGTCGGCAGAACAACCCATTACTTACCGGTGACGCAGGGGTG
GGTAAAACCGCCATTGTTGAAGGGCTAGCATTGGCTATTGCTGCTGGCTCAATGCCACCAGCATTAAGCCAGGTAAGCCT
GTTGTCATTAGATATTGTGGCGCTCTCAGCGGGTGCCAGCATGAAAGGTGAATTTGAAGCGCGCCTGAAGAGTGTCTTGG
ATGAAGCGATAGCGGCAGAAAAGCCCGTTATTTTGTTTATCGATGAAGTACACACACTTATTGGCGCGGGTGGCAATGCC
GGGACCGGCGATGCGGCGAACTTATTGAAACCTGCATTGGCGCGTGGCCAGTTACGTACCATTGGTGCGACAACGTGGAG
CGAGTTCAAGCGTCACATTGAGAAGGATCCGGCACTCACCCGTCGTTTCCAAGTACTTCAAGTTGATGAGCCCGATGAGA
ACACGGCGATCTCCATGTTACGGGGCCTGATACCTGCGCTAGAAAAGCACCACGGCGTGTGGATTATGGACGAAGCTTTA
CAGGCGGCAGTACGGTTGTCTCATCGTTATATCCCTGCGCGTCAGTTGCCGGATAAAGCGATAAGTCTGCTTGATACGGC
TTGTGCACGGATCGCTGTCGCGCAGTTTTCACAACCAATAGAGCTACAGCACTTAACCTTCCAGAGTGAGACGGCGCAAA
CTGAGCTGGTTTCCTTAGAGAAAGCGCGGCACTTTGGTAAAGCGCAGGATGCGCGTACTGAGCAGTTGAAAACATCCATT
GCTGAACATGGCGAGGCTGCGGATAAGCTTGATCAGCGTTGGCAGGCAGAACGCGAATTGGTATCAGCGATTACGACCAT
AAGAACCGCACTGTATGACTTGGTTTCTCAGCCAGAGCCTGATGAGGAAAAACGTCGGGCTTATCAAGCGCAATTAGTTC
AGTTGGAAGCGCAGCTTTCTCAGGTTCGCACTTCACTGCCGTTAGTGCAGACAGAAGTCAACGCTGAAGTGATTGCCAGT
ATCGTTGCGGATTGGACCGGCATTCCGGTTGGGCAAATGCTCAAAGACGATATTCGGGCGGTAATGGAGTTGCCACAGCG
CCTTGAAGCACGTGTTATTGGTCAGCCCCATGCATTGATGCAACTGGGTGAAAATATTATGACCGCACGCGCTGGCCTGT
CAGACCCAAGGAAACCATTGGGGGTCTTTATGTTAGTGGGGCCTTCAGGTGTGGGTAAAACAGAGACGGCCTTAGCGATC
GCCGAGAGCATGTATGGTGGTGAACAGAATATGATCACTATCAATATGAGCGAATATCAGGAATCGCATACCGTTTCCTC
TTTAAAAGGTTCTCCACCGGGATATGTTGGATACGGTGAAGGCGGTGTGTTAACGGAAGCTGTGCGCCGTAAGCCATATA
GTGTTGTGTTGTTAGATGAAATCGAAAAAGCGCACTCTGATGTACATGAGTTATTCTTCCAAGTGTTTGATAAAGGCCAA
ATGGAAGATGGTGAAGGGCGTTTTATCGATTTTAAAAATACTATCTTGTTGTTAACCAGTAATGTGGGCAGCGAGTTACT
GAGTAACTTATTAGCTGATCCAGATACTGCACCGGATCAGGATGGAATATTAAGTGCGTTGCAACCTGAATTGCTGAAAG
TTTTCCCCGCAGCATTTTTAGGGCGAGTTACGGTTATTCCTTATCTTCCGTTACAGCAAGATGCATTGCAGCATATTGTA
CGGTTGCATTTAGATCGGATTGGCGCTCGTTTATACTCGCAGCATCAATTGACACTGAAATACAGTGATGAAGTGGTTGA
AGATGTTGTTAGCCGCTGTGCGGTCTCAGAGACCGGTGCGCGTATGCTGATCCGTTACATTGAACAAAATATTACGCCAA
AAATAGGTAAATATATTTTAGGTGATAGTGATGTGAAGCCTGAGCAAATTATTTTCGTTCATAAAAATGAAAATGGATTC
GTGATCGCTTTACAGTGTAAAGATGACGAAAACTAA

Upstream 100 bases:

>100_bases
TTAGTCTTAGCCGCAGAAATAGTTCATGGTGCATCAAGCATTATTTCATGAACAATTTAAACTACACATGAACGCCGTTA
AAAAGACCAGGATAAAAAAC

Downstream 100 bases:

>100_bases
AGATATCACGTTTAAGCGGGTATCGATCCTATAGACTTTTATCTCAGTAATACTTATTGCAGATGGACATGCTAAAGGAT
GAAAAGGAATTTGCTATTTC

Product: Clp ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFAVDVDAFERELAQALAKLPVG
ATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEAN
EAASDGSPLYDGALPGEASNAIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAEKPVILFIDEVHTLIGAGGNA
GTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEAL
QAAVRLSHRYIPARQLPDKAISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLSQVRTSLPLVQTEVNAEVIAS
IVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAI
AESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFLGRVTVIPYLPLQQDALQHIV
RLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGARMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGF
VIALQCKDDEN

Sequences:

>Translated_891_residues
MAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFAVDVDAFERELAQALAKLPVG
ATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEAN
EAASDGSPLYDGALPGEASNAIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAEKPVILFIDEVHTLIGAGGNA
GTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEAL
QAAVRLSHRYIPARQLPDKAISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLSQVRTSLPLVQTEVNAEVIAS
IVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAI
AESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFLGRVTVIPYLPLQQDALQHIV
RLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGARMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGF
VIALQCKDDEN
>Mature_890_residues
AITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFAVDVDAFERELAQALAKLPVGA
TSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEANE
AASDGSPLYDGALPGEASNAIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGVG
KTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAEKPVILFIDEVHTLIGAGGNAG
TGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEALQ
AAVRLSHRYIPARQLPDKAISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSIA
EHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLSQVRTSLPLVQTEVNAEVIASI
VADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAIA
ESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQM
EDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFLGRVTVIPYLPLQQDALQHIVR
LHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGARMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGFV
IALQCKDDEN

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=34.5637583892617, Blast_Score=159, Evalue=9e-39,
Organism=Escherichia coli, GI1788943, Length=726, Percent_Identity=41.4600550964187, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1787109, Length=321, Percent_Identity=39.8753894080997, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320464, Length=688, Percent_Identity=41.4244186046512, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6323002, Length=702, Percent_Identity=36.039886039886, Blast_Score=431, Evalue=1e-121,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97759; Mature: 97628

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFA
CCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VDVDAFERELAQALAKLPVGATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLAL
HCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCEEEEEHHHHHHHHHCCCHHHHHH
LTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEANEAASDGSPLYDGALPGEASN
HHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCC
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAE
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCC
KPVILFIDEVHTLIGAGGNAGTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALT
CCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCHHHH
RRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEALQAAVRLSHRYIPARQLPDKA
HHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHCCHHH
ISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QVRTSLPLVQTEVNAEVIASIVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALM
HHHHHCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAIAESMYGGEQNMITINMSEYQ
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHH
ESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
HHHHHHHCCCCCCCEEECCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCC
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFL
CCCCCCCEEEECCEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GRVTVIPYLPLQQDALQHIVRLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGA
CHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHH
RMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGFVIALQCKDDEN
HHHHHHHHHCCCHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCC
>Mature Secondary Structure 
AITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFA
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
VDVDAFERELAQALAKLPVGATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLAL
HCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCEEEEEHHHHHHHHHCCCHHHHHH
LTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEANEAASDGSPLYDGALPGEASN
HHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCC
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAE
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCC
KPVILFIDEVHTLIGAGGNAGTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALT
CCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCHHHH
RRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEALQAAVRLSHRYIPARQLPDKA
HHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHCCHHH
ISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QVRTSLPLVQTEVNAEVIASIVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALM
HHHHHCCHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAIAESMYGGEQNMITINMSEYQ
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHH
ESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
HHHHHHHCCCCCCCEEECCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCC
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFL
CCCCCCCEEEECCEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GRVTVIPYLPLQQDALQHIVRLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGA
CHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHH
RMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGFVIALQCKDDEN
HHHHHHHHHCCCHHHHHEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10986262 [H]