Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 218929978

GI number: 218929978

Start: 3269085

End: 3269564

Strand: Reverse

Name: tadA [H]

Synonym: YPO2923

Alternate gene names: 218929978

Gene position: 3269564-3269085 (Counterclockwise)

Preceding gene: 218929979

Following gene: 218929976

Centisome position: 70.26

GC content: 55.42

Gene sequence:

>480_bases
ATGCGCCATGCCTTAACGCTGGCGCTGCGAGCGCAGGAAGAGGGTGAAGTTCCGGTGGGGGCAGTGCTGGTCTTGGGGAA
TAAGGTGATTGGTGAAGGGTGGAACCGGCCAATTCGCGATAATGACCCAACTGCTCATGCGGAAATTATGGCGCTACGCC
AAGGTGGGCAGGCGGTACAGAATTATCGCCTGTTGGATGCCACCTTATATGTGACGCTGGAACCTTGCGTGATGTGCGCC
GGAGCCATGGTACACAGCCGGATCCGCCGGTTGGTTTATGGCGCAAATGATGTAAAAACTGGCGCCGCGGGGTCGCTGGT
AGATATTTTGCGCCACCCTGGGATGAACCACCAAATAGAGGTCAGTGCTGGCATACTGGCGATTGCGTGTTCCCATCAAT
TGAGTGCGTTCTTTCGCCAACGCCGTGAGCAGCAGAAAGCATTGAAACAAGCACAGCGGGCAGCAGAAGGTAAATTCTGA

Upstream 100 bases:

>100_bases
TGCCAGAGAGGTTAATGTGTCTGCTGATAATAGTTTGCCTGCTGATAATGGCTTGTCTTCTGAATGTGATTCTCCTGCTG
AATACAGCGATGAGTACTGG

Downstream 100 bases:

>100_bases
CGGTGGCCAGGTGATGCGCCGCCCAGCATGTTATGACGGGCGGCGGTTGGTGACTAAATCACGGTGTAATTAAGGTTGAA
CGACTGCCGACGAGTGACTG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCA
GAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF

Sequences:

>Translated_159_residues
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCA
GAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF
>Mature_159_residues
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCA
GAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=165, Percent_Identity=32.7272727272727, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI145693172, Length=156, Percent_Identity=71.7948717948718, Blast_Score=235, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17541138, Length=144, Percent_Identity=36.1111111111111, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=42.7083333333333, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=32.4137931034483, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17376; Mature: 17376

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQ
CCCCEEEEEECCCCCCCCEEEEEEECCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHH
NYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIE
HEEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEE
VSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALRQGGQAVQ
CCCCEEEEEECCCCCCCCEEEEEEECCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHH
NYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIE
HEEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEE
VSAGILAIACSHQLSAFFRQRREQQKALKQAQRAAEGKF
ECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]