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The map label for this gene is hcaT [H]

Identifier: 218929963

GI number: 218929963

Start: 3246571

End: 3247728

Strand: Reverse

Name: hcaT [H]

Synonym: YPO2904

Alternate gene names: 218929963

Gene position: 3247728-3246571 (Counterclockwise)

Preceding gene: 218929964

Following gene: 218929961

Centisome position: 69.79

GC content: 50.17

Gene sequence:

>1158_bases
ATGGTATTGCAATCAACACGTTGGCTATCGCTCAGCTATTTCACCTATTTTTTTTCTTATGGCATTTTTTTGCCTTTTTG
GGGGCTCTGGTTAGAAGGTGAAGGTATCCCCCCGGAAACCATCGGTATTTTGCTCGGTGCTGGTTTACTCTCCCGCTTCC
TTGGCAGCCTCATTATTGCTCCGAGAGTAAAAGATCCTTCTCATCTGGTTACTGCAATCCGTATTTTGGCACTTCTGACG
TTAGCGTTTGCGGTCGGTTTTTGGTTTGGTAACGGCTGGGCTTGGTTGATGGTGGTTATCGCAGGTTTTAACCTGTTCTT
TGGCCCACTGGTACCATTGACGGATGCTTTGGCTGCGACGTGGCAAAAACAGATCACCATGGATTACGGCAAGGTCCGGT
TATGGGGGTCGCTGGCGTTTGTTATCGGCTCTGCGCTGACGGGAAAATTGGTATCCGTTTGGGGCCATCCCGCTATTCTC
TACAGCCTGCTGTTTGGTGTGACAGCGATGTTGCTGGGGGCATTGTTACGGCCTGGTGTGATGCCACGGGGTGAGGTTAA
ACATCGCAATGTTGCTGCAACGCCATGGAAGGTTCTATTATCCGAGCCGCAAGTTTGGCGCTTTTTGCTCTGTGTGACGT
TATTACAGGGTGCCCACGCGGCTTACTACAGTTTCAGTTCTATTTACTGGAAAGATGCCGGTTATTCCCCCGCAACCATC
GGCTATTTGTGGTCGCTGGGGGTTGTGGCCGAAATTCTGGTATTTGCGTTCAGTCACATCCTTTTCCGTCGATGGACAGC
CCGTAGCTTATTACTGCTCTCAGCGGTAAGTGGGATAATCCGCTGGAGCTTAATGGCTTCAACGACTGAATTGCCTTGGT
TGATTTTTATCCAAATTTTACATTGTGGTTCGTTTACTGTCTGCCATCTGGCCGCGATGCGTTTCATTTCGGCCCGCAGT
GGGGCGGATGTGATCCGTTTGCAATCAGTCTACTCGGCGCTAGCGATGGGCGGCGGTATTGCGGTGATGACAGTGATTTC
CGGCTTCTTATTTGAGAATTATCAGAGTGGGGTCTTTTGGGTTATGGCGCTCATTGTTATTCCGGCGCTGTTTATCCGGC
CACGAGTGGCCGCGAACCCAAATGAATTAGCCAGCTAA

Upstream 100 bases:

>100_bases
TTTTAACGTGAAGTTTGTCACAAAAAATCCAGTGTTGAGACGGTAAAGTTGCTAGCGGAGGAGGCCTCTGTCACAGTGAC
GGGCTGACCCCGGAGGAATC

Downstream 100 bases:

>100_bases
GGCAGTTCCAATATGCGGCATAACTGAATACTTTGCGGCTCAGTTAACGGAAATGATATCTGAATCAGCGGCGGCGCTGA
TTCAGTTGATTGCAAAACAT

Product: putative 3-phenylpropionic acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MVLQSTRWLSLSYFTYFFSYGIFLPFWGLWLEGEGIPPETIGILLGAGLLSRFLGSLIIAPRVKDPSHLVTAIRILALLT
LAFAVGFWFGNGWAWLMVVIAGFNLFFGPLVPLTDALAATWQKQITMDYGKVRLWGSLAFVIGSALTGKLVSVWGHPAIL
YSLLFGVTAMLLGALLRPGVMPRGEVKHRNVAATPWKVLLSEPQVWRFLLCVTLLQGAHAAYYSFSSIYWKDAGYSPATI
GYLWSLGVVAEILVFAFSHILFRRWTARSLLLLSAVSGIIRWSLMASTTELPWLIFIQILHCGSFTVCHLAAMRFISARS
GADVIRLQSVYSALAMGGGIAVMTVISGFLFENYQSGVFWVMALIVIPALFIRPRVAANPNELAS

Sequences:

>Translated_385_residues
MVLQSTRWLSLSYFTYFFSYGIFLPFWGLWLEGEGIPPETIGILLGAGLLSRFLGSLIIAPRVKDPSHLVTAIRILALLT
LAFAVGFWFGNGWAWLMVVIAGFNLFFGPLVPLTDALAATWQKQITMDYGKVRLWGSLAFVIGSALTGKLVSVWGHPAIL
YSLLFGVTAMLLGALLRPGVMPRGEVKHRNVAATPWKVLLSEPQVWRFLLCVTLLQGAHAAYYSFSSIYWKDAGYSPATI
GYLWSLGVVAEILVFAFSHILFRRWTARSLLLLSAVSGIIRWSLMASTTELPWLIFIQILHCGSFTVCHLAAMRFISARS
GADVIRLQSVYSALAMGGGIAVMTVISGFLFENYQSGVFWVMALIVIPALFIRPRVAANPNELAS
>Mature_385_residues
MVLQSTRWLSLSYFTYFFSYGIFLPFWGLWLEGEGIPPETIGILLGAGLLSRFLGSLIIAPRVKDPSHLVTAIRILALLT
LAFAVGFWFGNGWAWLMVVIAGFNLFFGPLVPLTDALAATWQKQITMDYGKVRLWGSLAFVIGSALTGKLVSVWGHPAIL
YSLLFGVTAMLLGALLRPGVMPRGEVKHRNVAATPWKVLLSEPQVWRFLLCVTLLQGAHAAYYSFSSIYWKDAGYSPATI
GYLWSLGVVAEILVFAFSHILFRRWTARSLLLLSAVSGIIRWSLMASTTELPWLIFIQILHCGSFTVCHLAAMRFISARS
GADVIRLQSVYSALAMGGGIAVMTVISGFLFENYQSGVFWVMALIVIPALFIRPRVAANPNELAS

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=377, Percent_Identity=66.57824933687, Blast_Score=496, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42464; Mature: 42464

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]