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The map label for this gene is sixA [H]

Identifier: 218929820

GI number: 218929820

Start: 3080950

End: 3081441

Strand: Direct

Name: sixA [H]

Synonym: YPO2748

Alternate gene names: 218929820

Gene position: 3080950-3081441 (Clockwise)

Preceding gene: 218929819

Following gene: 218929822

Centisome position: 66.2

GC content: 51.22

Gene sequence:

>492_bases
ATGCAAGTTTTCATTATGCGTCACGGTGACGCGGCACTTGATGCCGCTAGTGATGCGCAAAGGCCTCTAACTCTGTGTGG
TCAGGATGAATCACGTCAGATAGCAAGCTGGCTAAGTGAGCAGTCAGTGGATATCGATCAGATTCTGGTTAGCCCTTATT
TACGTGCCAGACAAACATTGGAAGTGGTGCGTGAGGTTATGGCGCTACCGGCAGAACCTGAAGTGATGCCCGAATTAACC
CCCGGTGGGGATGCCGCCTTCATTTGTTCTTATCTGCAAGCGTTGGCGAAAGAAGATTGCGCAGCAGTGTTAGTGATTTC
GCACTTGCCACTGGTCGGGTATTTGGTCGCCGAGCTTTGCCCAGGGCAATGCCCTCCGATGTTTGCTACTTCAGCCATCG
CCTGTATTGATCTCAATGGTAAGAGCGAAAAGGGTACGCTTGATTGGCAGGTGAGCCCTTCACAATTGTTGGCGAAGGCG
TGTCATGGATAA

Upstream 100 bases:

>100_bases
TATCGTTATGAAGTTTCTTTGCTTGCGGGCAAGGGTTTCGGCGGTACAGCACGCAAAGCGTTTCTGTATAGCGTTATTTG
GTTAACAAAAACGGTGCAAT

Downstream 100 bases:

>100_bases
GGCTCACCATGGGCTGTCATGACCAAGCCACCAGCCACTAAAATATAGCCTCCATCAACGTCTAACTGGCGCGGCATTCT
TGCCGCGCTTTCGCTTATTG

Product: phosphohistidine phosphatase

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MQVFIMRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAEPEVMPELT
PGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKA
CHG

Sequences:

>Translated_163_residues
MQVFIMRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAEPEVMPELT
PGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKA
CHG
>Mature_163_residues
MQVFIMRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTLEVVREVMALPAEPEVMPELT
PGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELCPGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKA
CHG

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=161, Percent_Identity=64.5962732919255, Blast_Score=207, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 17509; Mature: 17509

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVFIMRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTL
CEEEEEECCCCHHCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EVVREVMALPAEPEVMPELTPGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELC
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG
CCCCCCCHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MQVFIMRHGDAALDAASDAQRPLTLCGQDESRQIASWLSEQSVDIDQILVSPYLRARQTL
CEEEEEECCCCHHCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EVVREVMALPAEPEVMPELTPGGDAAFICSYLQALAKEDCAAVLVISHLPLVGYLVAELC
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PGQCPPMFATSAIACIDLNGKSEKGTLDWQVSPSQLLAKACHG
CCCCCCCHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]