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The map label for this gene is pta [H]

Identifier: 218929653

GI number: 218929653

Start: 2881104

End: 2883257

Strand: Direct

Name: pta [H]

Synonym: YPO2567

Alternate gene names: 218929653

Gene position: 2881104-2883257 (Clockwise)

Preceding gene: 218929652

Following gene: 218929655

Centisome position: 61.91

GC content: 52.69

Gene sequence:

>2154_bases
GTGTCCCGTACAATAATGTTGATCCCAACAGGCACCAGCGTTGGTTTAACCAGCGTCAGCTTAGGTGTCATCCGTTCCAT
GGAGCAAAAAGGGGTAAGCTTGAGCGTATTCAAGCCTATCGCCCAGCCACGTGCGGGTAATGATGCTCCTGACCAAACCA
CGACCATCATCCGGGCGAACTCCAGCATCACTGCTGCTGAGCCGCTGAACATGAACTACGTGGAAACCTTGCTGAGTTCT
AACCAGCAAGATGTCTTGATGGAAGAAATTGTTGCCCGTTATCACGAAAATACCAAAGACGCAGAAGTGGTTCTGGTTGA
AGGTCTGGTGCCTACACGCAAACATCAGTTTGCCAATGCACTGAACTATGAAATCGCTAAAACGCTGAACGCTGAAATCG
TCTTTGTTATTGCCCTTGGTAATGACTCGCCAGATCAGTTGAAAGAGCGTATCGAACTGGCCCGCTCCAGTTTTGGTGGC
AGCAAGAACAAAAACATCACTGGCGTTATCATCAATAAACTGAATGCCCCGGTTGATGAACAAGGCCGTACCCGCCCTGA
CCTGTCTGAAATCTTTGATGACTCCACCAAGGCCAGTGTTGCGAACATCGATCCAAGCCAGCTATTCGCTAACAGCCCGA
TCCCTGTTCTGGGTTGTGTACCGTGGAGCTTCGAGCTGATCGCCACCCGTGCCATTGATATGGCCAAGCACCTGAATGCC
CGCATTATTAACGAAGGCGATATTAAAACGCGTCGAGTTAAATCCGTGACATTCTGTGCGCGCAGCATCCCGCATATGCT
AGAGCACTTCCGTCCGGGTTCTCTGCTAGTGACCTCAGCAGACCGCCCTGATGTGTTGGTGTCTGCCTGTTTGGCGGCGA
TGAACGGTGTGGAAATCGGTGCCATCCTGCTGACGGGAGGTTATGCCATTGATGATCGTATCAATAATTTGTGTGAACGT
GCCTTCCAAACTGGCTTGCCAGTATTTATGGTTGATACCAACACCTGGCAGACCTCTCTGAGCCTGCAAAGCTTTAATCT
GGAAGTCCCAGCAGATGACCATGAGCGTGTTGAGAAGTTGCAAAACTACGTTGCCAGCCATATCAGCAGCGAGTGGATCG
ACTCCCTGACCGCCGCCTCTGAGCGCCCACGTCGCTTGTCTCCACCGGCCTTCCGTTATGAGCTGACTGAGTTGGCCCGT
AAAGCTGGCAAACGTATCGTACTGCCAGAAGGCGATGAGCCGCGCACCATTAAAGCCGCGTCTATCTGTGCTGAACGTGG
TATCGCCACTTGTGTCCTGTTGGGTAACCCGGAAGAGATCCAACGCGTTGCCACATCTCAAGGTGTTGAGTTGGGTAAAG
GCGTTGAAATTATCGACCCTGTTGCGGTACGTGAGCAATATGTTCCACGCTTGGTTGAGCTGCGTAAGAGCAAAGGCATG
ACCGAAGTGGTTGCCCGTGAACAGTTGGAAGACAACGTGGTTCTTGGCACCCTGATGCTGGAGAAAGGGGAAGTTGACGG
TCTGGTTTCTGGTGCAGTACATACCACCGCGAACACCATCCGCCCACCACTACAGTTAATCAAAACTGCACCGGGCAGTT
CGCTGGTCTCCTCTGTGTTCTTCATGCTGCTGCCTGACCAGGTTCTGGTGTACGGCGACTGCGCGATCAACCCAGATCCA
ACGGCGGAGCAACTGTCTGAGATTGCTATCCAATCGGCTGATTCTGCGGCAGCCTTTGGTATCGAACCTCGTGTGGCGAT
GATCTCGTACTCCACCGGTAACTCCGGTGCCGGTAGCGATGTCGAAAAAGTGCGTGAAGCGACTCGTCTCGCCCAAGAAA
AACGCCCAGATCTGATCATCGATGGCCCGTTACAGTATGATGCGGCAATCATGGCGGATGTGGCTAAATCTAAAGCGCCT
AACTCACCGGTAGCAGGTAGAGCGACCGTGTTCATCTTCCCAGACCTGAACACCGGTAACACCACCTATAAAGCCGTGCA
ACGTTCTGCCGACCTGATCTCTATCGGGCCGATGTTGCAAGGGATGCGCAAGCCGGTGAATGATTTGTCCCGTGGTGCGC
TGGTAGACGATATTGTCTATACCGTGGCGCTGACGGCGATCCAATCAGCTCAGGCTGATTCAGCCGCGTCTTAA

Upstream 100 bases:

>100_bases
TCATTTTAAGGTTAACGACCCGTAAATGATTCGGGTGAGTGAACGTAGCTAACCCCCTGCAACGCCAAGGATAAAGGGGA
TACCTTAAAGAGGCTTAGCC

Downstream 100 bases:

>100_bases
TCTTTGGGTTCGCATGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAACAGGCAGATCGTAAAGACGCCGTAAATACAT
CCATGTAGGCTCGAGCCGCG

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 717; Mature: 716

Protein sequence:

>717_residues
MSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRANSSITAAEPLNMNYVETLLSS
NQQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANALNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGG
SKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNA
RIINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAIDDRINNLCER
AFQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKLQNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELAR
KAGKRIVLPEGDEPRTIKAASICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGM
TEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAINPDP
TAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS

Sequences:

>Translated_717_residues
MSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRANSSITAAEPLNMNYVETLLSS
NQQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANALNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGG
SKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNA
RIINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAIDDRINNLCER
AFQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKLQNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELAR
KAGKRIVLPEGDEPRTIKAASICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGM
TEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAINPDP
TAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS
>Mature_716_residues
SRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRANSSITAAEPLNMNYVETLLSSN
QQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANALNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGGS
KNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNAR
IINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAIDDRINNLCERA
FQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKLQNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELARK
AGKRIVLPEGDEPRTIKAASICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGMT
EVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLVYGDCAINPDPT
AEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPN
SPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=712, Percent_Identity=87.3595505617977, Blast_Score=1290, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=317, Percent_Identity=38.801261829653, Blast_Score=225, Evalue=7e-60,
Organism=Escherichia coli, GI1788806, Length=346, Percent_Identity=30.9248554913295, Blast_Score=166, Evalue=7e-42,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77403; Mature: 77272

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRAN
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCEEEEEEC
SSITAAEPLNMNYVETLLSSNQQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANA
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
LNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGGSKNKNITGVIINKLNAPVDE
HHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
QGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNA
CCCCCCCHHHHHCCCCCCEECCCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
RIINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
AILLTGGYAIDDRINNLCERAFQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKL
EEEEECCEEHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHH
QNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELARKAGKRIVLPEGDEPRTIKAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEHHH
SICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
TEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
HHHHHHHHHCCCEEEEEEEEECCCCCHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCH
VEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRAGNDAPDQTTTIIRAN
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCEEEEEEC
SSITAAEPLNMNYVETLLSSNQQDVLMEEIVARYHENTKDAEVVLVEGLVPTRKHQFANA
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
LNYEIAKTLNAEIVFVIALGNDSPDQLKERIELARSSFGGSKNKNITGVIINKLNAPVDE
HHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
QGRTRPDLSEIFDDSTKASVANIDPSQLFANSPIPVLGCVPWSFELIATRAIDMAKHLNA
CCCCCCCHHHHHCCCCCCEECCCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
RIINEGDIKTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIG
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
AILLTGGYAIDDRINNLCERAFQTGLPVFMVDTNTWQTSLSLQSFNLEVPADDHERVEKL
EEEEECCEEHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHH
QNYVASHISSEWIDSLTAASERPRRLSPPAFRYELTELARKAGKRIVLPEGDEPRTIKAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCEEHHH
SICAERGIATCVLLGNPEEIQRVATSQGVELGKGVEIIDPVAVREQYVPRLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
TEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
HHHHHHHHHCCCEEEEEEEEECCCCCHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCH
VEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSAQADSAAS
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]