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The map label for this gene is sbcB [H]

Identifier: 218928697

GI number: 218928697

Start: 1773897

End: 1775327

Strand: Reverse

Name: sbcB [H]

Synonym: YPO1558

Alternate gene names: 218928697

Gene position: 1775327-1773897 (Counterclockwise)

Preceding gene: 218928702

Following gene: 218928694

Centisome position: 38.15

GC content: 49.13

Gene sequence:

>1431_bases
ATGTCAGATAAAAATAAGCAACCAACATTTTACGTCCACGATTATGAAACCTTCGGCCAGCGGCCAGCCTTGGATAGACC
TGCGCAATTTGCCGGGGTACGTACCGATCTGGATTTCAATCTCGTCGAAGAGCCATTGGTCATTTACTGCAAGCCCGCAG
ATGATTATCTGCCACAGCCCGAAGCGGTGATGATAACCGGTATTACCCCCCAACATGCTTTAGCCAACGGGGTCAATGAA
GCTGAGTTTTCCCGCCAAATACACCAGGCCTTTTCGGTACCCGGCACCTGTATCCTCGGCTACAACAATATTCGTTTTGA
TGATGAAGTCAGTCGCAACATTTTCTATCGTAATTTTTATGATCCTTATGCCTACAGTTGGCAGGGGGGAAATTCCCGTT
GGGATCTGTTGGATGTGATGCGCGCCTGCTATGCCCTGCGCCCAGAAGGTATTGTTTGGCCCGAAAATGATGATGGCCTG
CCCAGCTTTAAACTGGAACATTTGACCAAAGCCAATGGCGTCGAACATTTACAGGCACATGATGCGATGTCCGATGTCTA
CGCCACCATTGCAATGGCAAAATTGGTGAAACAGGCCCAACCCCGTCTGTTTGATTATCTGTATCAGCACCGCAGTAAGC
ATAAGATCAATGCGTTGATTGATATCGCGGAGATGACACCACTGGTTCATGTGTCTGGCATGTTTGGTGCCGCACGGGGC
AACACCAGTTGGGTGGCACCGCTGGCCTGGCACCCCGAGAATAAAAATGCGGTAATTATGTGTGATCTGGCCGGGGATAT
GTCCCCATTACTGGAGTTGGACAGCGATACATTGCGCGAACGTCTGTATACCCGCCGTGACAAGCTCCAAGCCCAAGAGT
CGGCAATCCCTATCAAACTGGTACATATCAATAAATGTCCGGTATTGGCTCCCGCGAAAACCCTGCTGCCCGAGAATGCT
GATCGCTTGGGGATTGATCGCCAGCGTTGTTTGCAAAATCTACAACTGCTGCGGCAAAACCCACAGGTGCGTGAAAAAGT
GGTCGCGCTGTTTGCACAAGCTGAGCCATTCGCGGTTACCGATGATGTGGATACACAGTTGTATAACGGCTTTTTCAGTG
ATGCTGATCGCGCCACCATAAAGATTATCCAGCAAACTGAGTCACAAAATCTGCCAGCACTGGATTTGACATTTCAGGAC
CCACGGTTGGAGGCCCTGTTATTCCGCTTCCGCGCCCGTAACTACCCGAATACCTTGAATGACAGTGAACAACAGCGTTG
GTTACAGCATCGCCGTGAAGCGCTTAGCCCTGAACGGGTACAAGATTATGTTTTGCAACTGGAACAATTTTATAACCAGT
ATGAAGACGATAAAGAGAAACTTGCGCTGCTAAAAGCGTTGTTTGAATATGCCAAGGGATTAGTGAGTTAA

Upstream 100 bases:

>100_bases
ATGATATTCTAGCGTCAACGTCATCCGTCGCTGCGGGTTGCCTTCTGCAAGCAGATCCCACCCGAATATGACCACGATAA
ATGAAGGGTTAAACCGAATA

Downstream 100 bases:

>100_bases
TATTTGCAGATAAAACGCCGCCAGAGAGCTGAGATTATTGGGCTGCCTGTGCGGCAGTGAACGTTATACCCCGCGCAGGG
AGTGAAGCGTTGACTTTCTA

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNE
AEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGL
PSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARG
NTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENA
DRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQD
PRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS

Sequences:

>Translated_476_residues
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNE
AEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGL
PSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARG
NTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENA
DRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQD
PRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
>Mature_475_residues
SDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNEA
EFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLP
SFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARGN
TSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENAD
RLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDP
RLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=475, Percent_Identity=73.0526315789474, Blast_Score=741, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54622; Mature: 54491

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQP
CCCCCCCCEEEEECHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
EAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCEEEECCC
DPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAH
CCCCEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHCCHHHHHHH
DAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
NTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKL
CCCEEEEEEECCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
VHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVT
EEECCCCCCCCHHHHCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEC
DDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLN
CCCHHHHHHHHHCCCCHHHHHHEEHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCC
DSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQP
CCCCCCCEEEEECHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
EAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFY
CEEEEECCCHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHCEEEECCC
DPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAH
CCCCEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHCCHHHHHHH
DAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARG
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
NTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKL
CCCEEEEEEECCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEE
VHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVT
EEECCCCCCCCHHHHCCCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEC
DDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLN
CCCHHHHHHHHHCCCCHHHHHHEEHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCC
DSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]