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The map label for this gene is fabA [H]

Identifier: 218928577

GI number: 218928577

Start: 1623371

End: 1623889

Strand: Reverse

Name: fabA [H]

Synonym: YPO1430

Alternate gene names: 218928577

Gene position: 1623889-1623371 (Counterclockwise)

Preceding gene: 218928578

Following gene: 218928575

Centisome position: 34.89

GC content: 47.4

Gene sequence:

>519_bases
ATGGTAGATAAACGCGAATCCTATACAAAAGAAGACCTTGAAGCATCCGGCCGTGGCGAGTTGTTTGGCGCTGGTGGGCC
ACCCTTACCCGCAGGCAATATGTTAATGATGGACCGTATTGTCAAAATGATAGAAGACGGTGGCAGCCATAATAAAGGTT
ATGTGGAAGCGGAACTGGATATCAATCCAGATCTATGGTTCTTCGGTTGCCATTTTATCGGTGATCCCGTCATGCCTGGC
TGTCTGGGCCTTGATGCCATGTGGCAGTTGGTTGGTTTCTATCTCGGCTGGCTCGGTGGCGAAGGCAAAGGCCGCGCACT
GGGTGTTGGTGAAGTTAAATTCACCGGCCAGGTGCTGCCAGATGCGAAAAAAGTGACATACCGTATTAATTTTAAACGCG
TGATTATGCGTAAATTAATTATGGGCGTTGCGGATGGTGAAGTCTTGGTTGATGGCAAAGTGATTTACACTGCCACTGAT
TTGAAAGTAGGTCTGTTTAAAGACACCAACGCTTTCTAA

Upstream 100 bases:

>100_bases
TACGCTGGCTAAACTGGTTCAACCAGGGCTAATCGGACTTGCTCAGCGTACAGCTGTACGCTATTCTGCGCACTTCACTA
ACATAAGGCTTACTGAGAAC

Downstream 100 bases:

>100_bases
TACGAATAAGTCAATGCATTGTAAAATAAGGCGAATATGATTAATCATGTCGCCTTATTGTTTTTACGTGATATACCACA
TGAGATTCAGGAGATAGCCT

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATD
LKVGLFKDTNAF

Sequences:

>Translated_172_residues
MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATD
LKVGLFKDTNAF
>Mature_172_residues
MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPG
CLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATD
LKVGLFKDTNAF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=172, Percent_Identity=87.2093023255814, Blast_Score=309, Evalue=5e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18810; Mature: 18810

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELD
CCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEE
INPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLP
CCCCEEEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCC
DAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF
CCEEEEEEECHHHHHHHHHHHCCCCCCEEECCEEEEEEECEEEEEECCCCCC
>Mature Secondary Structure
MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELD
CCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEE
INPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLP
CCCCEEEEEEEECCCCCCCCHHCHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCCC
DAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF
CCEEEEEEECHHHHHHHHHHHCCCCCCEEECCEEEEEEECEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA