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The map label for this gene is yeiR [H]

Identifier: 218928430

GI number: 218928430

Start: 1436476

End: 1437459

Strand: Reverse

Name: yeiR [H]

Synonym: YPO1277

Alternate gene names: 218928430

Gene position: 1437459-1436476 (Counterclockwise)

Preceding gene: 218928433

Following gene: 218928429

Centisome position: 30.89

GC content: 48.37

Gene sequence:

>984_bases
ATGACAAAGACCAATTTAATTACCGGATTTTTAGGTTGTGGCAAAACCACAACTATCCGGCACTTACTCGCACAGAAGCC
GGAACATGAAAAATGGGCGGTGCTGGTCAATGAATTTGGTGAGATTGGTATTGATGGCGCTCTGTTGGCGGATAGCGGTG
CTGTTTTAAAAGAGATCCCAGGGGGCTGTATGTGCTGTGTTAATGGGCTACCGATGCAAATTGGCCTGAACATGCTGTTG
CAGCAGGCAAAACCAGATCGCCTGCTCATTGAGCCAACCGGGCTGGGCCACCCGAAACAAATTCTGTCATTATTAACGTC
TGATATTTATCAGCCTTGGATTGACTTACGCGCCACACTTTGTCTGCTGGATGCCCGCCAACTGAGTGAACCCCGCTATA
CCGAAAATGAAAATTTCCGTGACCAACTGGCGGCGGCAGATATCATTGTGGTCAACAAGCAAGACACTTACCGCTCGGCC
GATAACGCGGTGTTACAACAATGGCAACAAAAGCAGCCATTATCGCGGCCGCTGTATCATAGCGAATATGGCAAACTCGA
CGTGGCCCTGCTCGACCAACCACACAGTAATAAAGACGAACTTCCTTCTGGTACACATCATCACGGCACATCACAGCCAA
AAGGATTAGCCGCATTACGTCTGAAAGGGGCCGAACCCTGGCGTCGGGCATTAAATCGGGGGCAAGGGTATCTGAGCTGT
GGCTGGGTATTTGATGCCAACACCGTTTTTGATACCGTGCCATTATTGGAGTGGGTACGATTGAACCCAGCAGAACGGGT
AAAAGGTGTCATGCGCATCCCGGAAGGAACCTTGATGGTTAATCGACAAGGTAATGACTTACAAATAGACACTCGCCAAA
TACCCCCGCTGGATAGCCGCATTGAATTGATTAGCGCCACTGATATTGATTGGAACGTATTGCAACATGATTTATTAAAA
ATTCGTTTACGTAACGGGGTATGA

Upstream 100 bases:

>100_bases
AAGCCTAATTGGCCTTATTTCCTTTCAGGTTGAAAGGGTAATAAATAGCCATATAATTTGTAAATCATATAAAAATATTT
TTGTATTTTGGAGATCCAGC

Downstream 100 bases:

>100_bases
TGTCTCCCCATTTTTATTTTCTTTCCGTTGTGTACATTTTTAATTTATAGGTTACCGCATGACTCGTCGTAATTTACCGA
CAATATTGCTCCTCAATTTA

Product: putative cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLL
QQAKPDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVVNKQDTYRSA
DNAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHSNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLK
IRLRNGV

Sequences:

>Translated_327_residues
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLL
QQAKPDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVVNKQDTYRSA
DNAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHSNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLK
IRLRNGV
>Mature_326_residues
TKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLLQ
QAKPDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVVNKQDTYRSAD
NAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHSNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSCG
WVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLKI
RLRNGV

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI223941779, Length=169, Percent_Identity=33.7278106508876, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI33469141, Length=174, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI148727351, Length=174, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI146231952, Length=174, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788499, Length=324, Percent_Identity=67.2839506172839, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI87082430, Length=194, Percent_Identity=30.9278350515464, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36593; Mature: 36461

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQIGLNMLLQQAKPDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATL
CCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CLLDARQLSEPRYTENENFRDQLAAADIIVVNKQDTYRSADNAVLQQWQQKQPLSRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SEYGKLDVALLDQPHSNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEE
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSR
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCC
IELISATDIDWNVLQHDLLKIRLRNGV
EEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQIGLNMLLQQAKPDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATL
CCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CLLDARQLSEPRYTENENFRDQLAAADIIVVNKQDTYRSADNAVLQQWQQKQPLSRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SEYGKLDVALLDQPHSNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEE
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSR
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCC
IELISATDIDWNVLQHDLLKIRLRNGV
EEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]