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The map label for this gene is rtn [H]

Identifier: 218928427

GI number: 218928427

Start: 1432522

End: 1433895

Strand: Reverse

Name: rtn [H]

Synonym: YPO1274

Alternate gene names: 218928427

Gene position: 1433895-1432522 (Counterclockwise)

Preceding gene: 218928428

Following gene: 218928426

Centisome position: 30.81

GC content: 43.45

Gene sequence:

>1374_bases
ATGTCTCAGCTTATCCCACTGAGCACCCAATCGTGCGAACAAGCCAGCCCAACTCTTCATTATCGTGCCGCCTTTACCAA
TGGTGTCAGAGCCTTTTTATTGGTCAGGGAAGGCGTTGCTTATTGCTCCTCGGCAACGGGTGAAATGCACACGCCAGTCA
GTACGATCTACCCCAAAGTTAATTTATCCCAGCCACTGGATTTTAAAATTCAGCAAGGCACCCCCATGATGCCAAACAAG
CCTGCAATTGCCGTATGGCTGCGTCAAGCAGGCCGTGGAGATACGGGAATATTGGCGACGATGGAATTCAGTTTGCATCC
CTATCTATTAATGGGCCGTTCAGATAACGAAATGAGTGGCTCAGCGATTATTATTGATGGCTTAGCTATCACTACTTTTG
ATTCTAACGTCTTACCTATCAGCCAGTTACCTAATCTAAACGCCAGGGAGATTACATTACCTGGTTATCCGATTAAGATA
TTGATTTATCATAATAGTATAACGAAAAACGATATTAGAATGACCCTGTTAGGTGGCCTATTACTTGCCGGCTTGGTGGG
CATCTTGGCTTATTATATTTTAATCACCAAAAAAAGTGCTGAAGCTGAAATTTTACGGGGCATTAGGCGCGGTGAGTTTT
TCGTTGAATATCAACCGGTTTTTCGCTCACATAATCAGACAATATCAGGTTTAGAAGCCCTTATCCGTTGGCAACACCCG
ACTGAAGGGCGGATTTCGCCCGATATCTTCATTCCTTATGCCGAAACTCAACACCTGATACAGCCGCTGACAACGCACTT
GTTTGAGTTAATTATCAGAGATACCGCTCTTATGGTAAACCTGTTCCCGACGGGCGCTAAACTTGCCTTTAATATTTCAC
CGGCCCATCTTGCTGATGATGATTTTTGTCAGGACGTATCACGACTCTTGCAGCAATTAAATACCGATATTTTTACCCCC
GTATTCGAAATTACTGAGCGAGGTATGGTGCAAAAAGAGTTGGCCCTGAAGCAATTCGCCTGGCTGCATTCGCAAGGGAT
TCAAATCGCTGTCGATGATTTTGGCACCGGCCATAGCGCCCTGATCTATTTAGAACGCTTTACCTTAGATTATATTAAAA
TTGATCGCGGCTTTATCAGCACGATAGGCGAAAATACGGTGACAACGCCGGTATTAGATTCGGTATTAATTCTGGCAAAA
AAACTTAATATTGAAACTATCGCTGAGGGCATCGAGACTGAGCAACAACTTCACTATTTAGCTAAACATGGTGTCAATTA
CTTGCAGGGTTATTTACTCAGTAAGCCGCTGTCTGTTGAAGCTTTAGCTAAATTCTGTCATGAAAAGATGAGTAACAAAA
ACTTACTGGCTTAA

Upstream 100 bases:

>100_bases
GTTGTCATTACTGTATCGCAGCAGTGAAAATAAATTAACAACACAAAGTGGTAATATTATCACCTATGCCTCTCATTTCC
TTAATGAAATAACAACGACC

Downstream 100 bases:

>100_bases
TGTTTGCATTATCCCCCTGTAAGCTGGTAATTTCATTTGAGAAAATGATTATCTGCAGCTTCGCAGGAGATTGCCAACAA
TATGTTTTTACGCCTATTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNK
PAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKI
LIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHP
TEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTP
VFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAK
KLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA

Sequences:

>Translated_457_residues
MSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNK
PAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKI
LIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHP
TEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTP
VFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAK
KLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
>Mature_456_residues
SQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGTPMMPNKP
AIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKIL
IYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPT
EGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPV
FEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKK
LNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=447, Percent_Identity=44.7427293064877, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI87081980, Length=453, Percent_Identity=30.0220750551876, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081845, Length=452, Percent_Identity=30.5309734513274, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786507, Length=227, Percent_Identity=34.8017621145374, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787541, Length=251, Percent_Identity=33.4661354581673, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87081743, Length=272, Percent_Identity=29.4117647058824, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790496, Length=257, Percent_Identity=28.0155642023346, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081921, Length=242, Percent_Identity=28.9256198347107, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=28.936170212766, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082096, Length=231, Percent_Identity=29.004329004329, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI226510982, Length=252, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787055, Length=252, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787410, Length=137, Percent_Identity=27.7372262773723, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 50924; Mature: 50793

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKV
CCCCCCCCCCCHHHCCCCEEEEEHHHCCHHEEHHHHHHHHHHCCCCCCCCCCHHHHCCCC
NLSQPLDFKIQQGTPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSG
CCCCCCCEEECCCCCCCCCCCHHEEEEHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCC
SAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDIRMTLLGGL
CEEEEECEEEEEECCCCEEHHHCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHH
LLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCC
TEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADD
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCH
DFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSA
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEE
LIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIETEQQLHYL
EEEEEEHEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
HHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGEMHTPVSTIYPKV
CCCCCCCCCCHHHCCCCEEEEEHHHCCHHEEHHHHHHHHHHCCCCCCCCCCHHHHCCCC
NLSQPLDFKIQQGTPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSG
CCCCCCCEEECCCCCCCCCCCHHEEEEHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCC
SAIIIDGLAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDIRMTLLGGL
CEEEEECEEEEEECCCCEEHHHCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHH
LLAGLVGILAYYILITKKSAEAEILRGIRRGEFFVEYQPVFRSHNQTISGLEALIRWQHP
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCC
TEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKLAFNISPAHLADD
CCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCH
DFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSA
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEE
LIYLERFTLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIETEQQLHYL
EEEEEEHEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AKHGVNYLQGYLLSKPLSVEALAKFCHEKMSNKNLLA
HHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]