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The map label for this gene is intA [H]

Identifier: 218928267

GI number: 218928267

Start: 1243484

End: 1244683

Strand: Reverse

Name: intA [H]

Synonym: YPO1098

Alternate gene names: 218928267

Gene position: 1244683-1243484 (Counterclockwise)

Preceding gene: 218928268

Following gene: 218928266

Centisome position: 26.75

GC content: 45.92

Gene sequence:

>1200_bases
ATGGCAAGGACAACACGCCCCCTCACCCACACCGAAGTACAAAAAGCAAAAGCCACCGACAAAGACCTAACCCTCCATGA
TGGTGATGGTTTATTTTTGCTAGTCAAAACTACCGGCAAGAAAATTTGGCGTTTCCGCTATCAGCTTCCCAACAGTAGCA
AGCGCACTATGATCAGCCTCGGTGCTTACCCAGCACTATCCCTCGCAGATGCCAGAGAGATACGCGCAGAAAAACTAGCG
ATGTTAGTCAGAGGGACAGACCCTCAAACGAGGGCTGGTGAAGAGGCTGAAAAGCTCCAGATAGCGGAGGAAAGCATTTT
TGTGAATGTCGCCCGCAAATGGTTCGAGTTGAAAGAAAGCCATGTTAGCGCAGCCCATGCGAAAGATATTTGGCGTTCTA
TTGAAAAAGACATCTTACCCAGCATCGAAAATATTCCCATCCAAGAACTTAAAGCACGAACTCTGATTCAAGTATTGGAG
CCAATCAAAGCACGTGGAGCATTAGAGACGGTCAGGCGATTGGTACAACGTATAAACGAGATAATGATCTATGCGGTCAA
TGTAGGTTTGATTGATGCTAACCCAGCTTCAGGTATCGGTAATGCTTTTGAACGCCCCAAGAAGCAGCATATGCCCACCA
TCAGACCTGAAGAACTACCTAAACTCATGCGTACCATTGCCATGAGCAATCTCTCACTGCCAACCCGCTGCTTACTTGAA
TGGCAATTACTAACTCTGATACGCCCCGCTGAAGCATCAGCAACAGCTTGGATAGAGATCGATTTAGAGAATAAGCAGTG
GTGTATACCGGCAGAACGAATGAAAGCAAAGCGCGACCATATAGTCCCGTTGTCGGAACAAGCCTTAGAGTTGCTGGAAA
TAATGCGTCCAATTAGTGGTAATCGTCAGCACGTATTCCCAAGTCGCAATGACCCACGTAATCACATGAATAGCCAAACA
GCAAATGCAGCCTTGAAACGTATTGGTTATGGAGGGAAGCTCGTTGCTCACGGTTTACGTTCTATCGCCAGTACAGCCAT
GAATGAGGCTGGGTTTAATGCTGATGTGATTGAGGCTGCGCTAGCGCATAGTGATAAGAATGAAGTCAGGAAAGCTTATA
ATCGTTCTACCTATCTCATACAACGCCAAGAGTTAATGAATTGGTGGGGATTAGAGATATACACTAAAAGAAGTATTTAA

Upstream 100 bases:

>100_bases
CCAAGAGGATCCGGCTGAATCCAGTGTCTATTGGTATACAAATTGGTATACGCTAAGATAGGTATCAATGGACGTATACC
AATTAAGGGAAGAACCATAC

Downstream 100 bases:

>100_bases
CGTAAGTGAAAGTCATAGACGTTTCCCTTAGCACGTATTATCTTTTAGTATCACTCATAAAATGGACAGGCCACTAAAAT
GGATAGTGAAGACACATCTG

Product: putative prophage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLADAREIRAEKLA
MLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLE
PIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMSNLSLPTRCLLE
WQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSRNDPRNHMNSQT
ANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI

Sequences:

>Translated_399_residues
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLADAREIRAEKLA
MLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLE
PIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMSNLSLPTRCLLE
WQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSRNDPRNHMNSQT
ANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI
>Mature_398_residues
ARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLADAREIRAEKLAM
LVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLEP
IKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMSNLSLPTRCLLEW
QLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSRNDPRNHMNSQTA
NAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=390, Percent_Identity=57.6923076923077, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788690, Length=386, Percent_Identity=31.6062176165803, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI145693166, Length=392, Percent_Identity=34.4387755102041, Blast_Score=198, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45237; Mature: 45106

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISL
CCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEE
GAYPALSLADAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKES
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLEPIKARGALETVRRLVQRINE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMSNLSLPTRCLLE
HEEEEEEEEEEECCCCCCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
WQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISG
HHHHHHCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
NRQHVFPSRNDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAA
CCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI
HHCCCHHHHHHHHCCCHHEEEHHHHHHHHCCEEEEECCC
>Mature Secondary Structure 
ARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISL
CCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEEECCCCCCCEEEEE
GAYPALSLADAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKES
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLEPIKARGALETVRRLVQRINE
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMSNLSLPTRCLLE
HEEEEEEEEEEECCCCCCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
WQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISG
HHHHHHCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
NRQHVFPSRNDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAA
CCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI
HHCCCHHHHHHHHCCCHHEEEHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]